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| 1 | Photocatalytic decarboxylative coupling between α-oxocarboxylicacids and alkenes显示文摘Photocatalytic decarboxylative cross-coupling which achieves the derivatization of widespread organic acids has become a hot topic in organic synthesis.As special acids,α-oxocarboxylicacids show the great potential in running decarboxylation to construct ketone derivatives.In this article,we have developed a photocatalytic decarboxylative cross-coupling ofα-oxocarboxylic acids and olefins to the synthesis of diverse aryl ketones.Various alkenes andα-oxocarboxylicacids were compatible,generating the desired products in up to 90%yield.Preliminary mechanism studies suggest that a free radical pathway is involved in this process. | Ziyue Chen Fangling Lu Feng Yuan Juanjuan Sun Linyu Du Zhen Li Meng Gao Renyi Shi Aiwen Lei | 2019 | Science China Chemistry2019，62，11： | 2 |
| 2 | Synthesis and Photoluminescence Enhancement of Silver Nanoparticles Decorated Porous Anodic Alumina显示文摘Silver nanoparticles(Ag NPs) were successfully assembled in porous anodic alumina(AAO) templates via a green silver mirror reaction.The Ag NPs/AAO composite templates then were characterized by field emission scanning electron microscopy(FESEM),energy-dispersive X-ray microanalysis(EDX),and X-ray diffraction(XRD).Furthermore,the photoluminescence(PL) properties were also investigated.Compared with the blank AAO,the PL intensity of Ag NPs/AAO templates are enhanced and the maximum enhancement is 2.58 times.Based on the local electric field enhancement effect,the theoretical values were also deduced,which are basically coincident with the experimental. | Song Ye Yidong Hou Renyi Zhu Shulong Gu Jingquan Wang Zhiyou Zhang Sha Shi Jinglei Du | 2011 | Journal of Materials Science & Technology2011，27，2： | 1 |
| 3 | 肿瘤坏死因子相关的凋亡诱导配体对胰腺癌细胞抗肿瘤作用的研究(英文)显示文摘Objective: To investigate the antitumor effect of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) gene transfection mediated by adenovirus into human pancreatic carcinoma cell line Panc-1, and the mechanisms involved in this effect. Methods: TRAIL gene was transfected into pancreatic cancer cell line Panc-1 by an adenovirus vector (Ad-TRAIL). Level of TRAIL mRNA expression was determined using RT-PCR, and TRAIL protein synthesis was evaluated with Western blot. Cell-growth activities were determined by MTT assay. The bystander effect was observed by co-culturing the Panc-1 cells with the transfected TRAIL gene at different ratios. Apoptosis in pancreatic cancer cells was detected by flow cytometry. Procaspase-8 and procaspase-3 were determined by Western blot. Results: The stable overexpression of TRAIL was de-tected in Panc-1 cells transfected by Ad-TRAIL. Ad-TRAIL significantly inhibited of cell viability of Panc-1 cells. Furthermore, co-culture of cancer cells transfected with TRAIL with that nontransfected resulted in the cell death of both cells by bystander effect. Moreover, the percentage of apoptotic cells was significantly higher in the Ad-TRAIL-treatment group compared to the control groups (P < 0.01). And there was a diminished amount of procaspase-8 and procaspase-3 after infection with Ad-TRAIL. Conclusion: The overexpression of TRAIL gene in Panc-1 cells by Ad-TRAIL exerts its antitumor effects, and the mechanisms involved in this effect may be proapoptosis and bystander effect. | Rui Tian Renyi Qin Zhiyong Du Wei Xia Chengjian Shi | 2007 | The Chinese-German Journal of Clinical Oncology2007，6，5： | 0 |
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