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| 1 | Radioembolization for the treatment of unresectable hepatocellular carcinoma:A clinical review显示文摘Hepatocellular carcinoma(HCC)is the sixth most common cancer in the world.The majority of patients with HCC present with unresectable disease.These patients have historically had limited treatment options secondary to HCC demonstrating chemoresistance to the currently available systemic therapies.Additionally, normal liver parenchyma has shown intolerance to tumoricidal radiation doses,limiting the use of external beam radiation.Because of these limitations,novel percutaneous liver-directed therapies have emerged. The targeted infusion of radioactive microspheres (radioembolization)represents one such therapy. Radioembolization is a minimally invasive transcatheter therapy through which radioactive microspheres are infused into the hepatic arteries that supply tumor. Once infused,these microspheres traverse the hepatic vascular plexus and selectively implant within the tumor arterioles.Embedded within the arterioles, the 90Y impregnated microspheres emit high energy and low penetrating radiation doses selectively to the tumor.Radioembolization has recently shown promise for the treatment of patients with unresectable HCC. The objective of this review article is to highlight twocurrently available radioembolic devices(90Y,188Rh)and provide the reader with a recent review of the literature. | Saad M Ibrahim Robert J Lewandowski Kent T Sato Vanessa L Gates Laura Kulik Mary F Mulcahy Robert K Ryu Reed A Omary Riad Salem | 2008 | World Journal of Gastroenterology2008，14，11： | 14 |
| 2 | Diffusion-weighted magnetic resonance imaging to predict response of hepatocellular carcinoma to chemoembolization显示文摘AIM: To investigate whether intra-procedural diffusion- weighted magnetic resonance imaging can predict response of hepatocellular carcinoma (HCC) during trans- catheter arterial chemoembolization (TACE). METHODS: Sixteen patients (15 male), aged 59 ±11 years (range: 42-81 years) underwent a total of 21 separate treatments for unresectable HCC in a hybrid magnetic resonance/interventional radiology suite. Ana- tomical imaging and diffusion-weighted imaging (b = 0, 500 s/mm2) were performed on a 1.5-T unit. Tumor enhancement and apparent diffusion coefficient (ADC, mm2/s) values were assessed immediately before and at 1 and 3 mo after TACE. We calculated the percent change (PC) in ADC values at all time points. We compared follow-up ADC values to baseline values using a paired t test (α = 0.05). RESULTS: The intra-procedural sensitivity, specificity, and positive and negative predictive values (%) for detecting a complete or partial 1-mo tumor response using ADC PC thresholds of ±5%, ±10%, and ±15% were 77, 67, 91, and 40; 54, 67, 88, and 25; and 46, 100, 100, and 30, respectively. There was no clear predictive value for the 3-mo follow-up. Compared to baseline, the immediate post-procedure and 1-mo mean ADC values both increased; the latter obtaining statistical significance (1.48 ± 0.29 mm2/s vs 1.65 ± 0.35 × 10-3 mm2/s, P < 0.014). CONCLUSION: Intra-procedural ADC changes of > 15% predicted 1-mo anatomical HCC response with the greatest accuracy, and can provide valuable feedback at the time of TACE. | Johnathan C Chung Neel K Naik Robert J Lewandowski Mary F Mulcahy Laura M Kulik Kent T Sato Robert K Ryu Riad Salem Andrew C Larson Reed A Omary | 2010 | World Journal of Gastroenterology2010，16，25： | 13 |
| 3 | Human apolipoprotein A-I gene transfer reduces the development of experimental diabetic cardiomyopathy显示文摘 | Van Linthout S Spillmann F Riad A | 2008 | Circulation2008，117，： | 1 |
| 4 | Myeloid differenti- ation factor-88 contributes to TLRg-mediated modulation of acute eoxsaekievirus B3-indueed myoearditis in vivo 显示文摘 | Riad A Westermann D Eseher F | 2010 | Am J Physiol Heart Cite Physiol2010，298，： | 1 |
| 5 | A 200MHz CMOS Q- enhanced LC Bandpass Filter显示文摘 | W Kuhn F Stephenson A Elshabini - Riad | 1996 | IEEE Journal of Solid - State Circuit1996，31，8： | 1 |
| 6 | Service-Oriented Architecture A New Alternative to Traditional Integration Methods in B2B Applications显示文摘 | A M Riad Q F Hassan | | 0，，01： | 1 |
| 7 | Spinal meningio-mas:surgical outcome and literature review 显示文摘 | Riad H Knafo S Segnarbieux F | 2013 | Neuro-chirurgie2013，，1： | 1 |
| 8 | Predic- ting evacuation in two major disasters: risk percep- tion, social Influence, and access to resources显示文摘 | RIAD J K NORRIS F H RUBACK R B | 1999 | Journal of Applied Social Psychology1999，29，5： | 1 |
| 9 | Multi-residu-es determination of antimicrobials in fish tissuesby HPLC-ESI-MS/MS method 显示文摘 | Rezk M R Riad S M Khattab F I | 2015 | Journal of Chromatogr-aphy B2015，，978979： | 1 |
| 10 | Bleeding and infection with external ventricular drainage : a systematic review in comparison with adjudicated adverse events in the ongoing Clot Lysis Evaluating Accelerated Resolu- tion of Intraventricular Hemorrhage Phase III( CLEAR-III II-IV) trial 显示文摘 | Dey M Stadnik A Riad F | 2015 | Neurosurgery2015，76，3： | 1 |
| 11 | Spinal meningiomas: surgical outcome and literature review 显示文摘 | Riad H Knafo S Segnarbieux F | 2013 | Neurochirurgie2013，59，1： | 1 |
| 12 | A 200 MHz CMOS Q Enhanced LC Bandpass Filter显示文摘 | Kuhn W B Stephenson F W Riad A E | 1996 | IEEE J of Solid-State Circuits1996，31，8： | 1 |
| 13 | Metastatic non-small cell lung cancer in Brazil:treatment heterogeneity in routine clinical practice 显示文摘 | FAUZIA F N RIAD N Y BRUNO G K | 2007 | Clinics2007，62，4： | 1 |
| 14 | Femoral shaft fracture afterhip arthroplasty:a system for classification and treatmet显示文摘 | Mark HG Riad B Daniel F | 1999 | J South Ortho Assoc1999，32，： | 1 |
| 15 | Antigen capture ELISA technique for rapid detection of Salmonella Type imurium in fecal samples of diarrhoeic cow calves显示文摘 | Riad E M Tanios A I Elmoghny A F | 1998 | Assiut veterinary medical journal1998，39，78： | 1 |
| 16 | The response of the 7F8(A) NaI(Tl) well crystal to γ-radiations显示文摘 | SWAILEM F M RIAD M M | 1983 | Int J Appl Radiat Isot1983，34，10： | 1 |
| 17 | DESIGN AND SYNTHESIS OF ENERGETIC MATERIALS1显示文摘 | Laurence E Fried M Riad Manaa Philip F Pagoria Randall L. Simpson | 2001 | Annual Review of Materials Research2001，，： | 1 |
| 18 | Retrospective evaluation of bipolar hip arthroplasty in fractures of the proximal femur显示文摘 | Mazen S Julien G Riad F | | 0，，09： | 1 |
| 19 | Human apolipoprotein A-I gene transfer reduces the development of experimental diabetic cardiomyopathy显示文摘 | Van Linthout S Spillmann F Riad A | 2008 | Circulation2008，117，12： | 1 |
| 20 | Femoral shaft fracture after hip arthroplasty:a system for classification and treatment显示文摘 | Mark HG Riad B Daniel F | 1999 | J South Ortho Assoc1999，8，4： | 1 |
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