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| 1 | Who benefits from percutaneous closure of patent foramen ovale vs medical therapy for stroke prevention? In-depth and updated metaanalysis of randomized trials显示文摘BACKGROUND A few randomized clinical trials(RCT) and their meta-analyses have found patent foramen ovale closure(PFOC) to be beneficial in prevention of stroke compared to medical therapy. Whether the benefit is extended across all groups of patients remains unclear.AIM To evaluate the efficacy and safety of PFOC vs medical therapy in different groups of patients presenting with stroke, we performed this meta-analysis of RCTs.METHODS Electronic search of PubMed, EMBASE, Cochrane Central, CINAHL and ProQuest Central and manual search were performed from inception through September 2018 for RCTs. Ischemic stroke(IS), transient ischemic attack(TIA), a composite of IS, TIA and systemic embolism(SE), mortality, major bleeding,atrial fibrillation(AF) and procedural complications were the major outcomes.Random-effects model was used to perform analyses.RESULTS Meta-analysis of 6 RCTs including 3560 patients showed that the PFOC,compared to medical therapy reduced the risk of IS [odds ratio: 0.34; 95%confidence interval: 0.15-0.78; P = 0.01] and the composite of IS, TIA and SE [0.55(0.32-0.93); P = 0.02] and increased the AF risk [4.79(2.35-9.77); P < 0.0001]. No statistical difference was observed in the risk of TIA [0.86(0.54-1.38); P = 0.54],mortality [0.74(0.28-1.93); P = 0.53] and major bleeding [0.81(0.42-1.56); P = 0.53]between two strategies. Subgroup analyses showed that compared to medical therapy, PFOC reduced the risk of stroke in persons who were males, ≤ 45 years of age and had large shunt or atrial septal aneurysm.CONCLUSION In certain groups of patients presenting with stroke, PFOC is beneficial in preventing future stroke compared to medical therapy. | Khagendra Dahal Adil Yousuf Hussam Watti Brannen Liang Sharan Sharma Jharendra Rijal Pavan Katikaneni Kalgi Modi Neeraj TANDon Michael Azrin Juyong Lee | 2019 | World Journal of Cardiology2019，11，4： | 4 |
| 2 | 粉末冶金和微波烧结法制备Al−CNTs−Al2O3纳米复合材料的工艺−显微组织−性能之间的关系显示文摘采用粉末冶金和微波烧结工艺制备Al−2CNTs−xAl2O3纳米复合材料。研究工艺引起的显微组织特征与材料的物理、力学性能以及超声参数之间的相互关系。研究发现,复合材料的致密化和尺寸变化等物理性能与纳米复合粉体的形貌和粒径密切相关。当Al2O3含量为10%(质量分数)、球磨时间大于8 h、颗粒被大量细化时,材料的密度最大。Al2O3含量、纳米强化相的分布和晶粒尺寸对材料的力学性能有显著影响,当Al2O3含量为10%(质量分数)、Al2O3纳米颗粒球磨时间为12 h、碳纳米管均匀分布时,可形成高密度位错和大量晶粒细化,从而获得最佳的硬度和强度。同时,纵波和横波速度及衰减随着Al2O3含量和球磨时间的增加而线性增加。超声速度和衰减的变化取决于碳纳米管和Al2O3在基体中分布的均匀程度及其较小的颗粒间距。经过较长的球磨时间,Al2O3含量越高,碳纳米管和Al2O3分布越均匀,超声波的速度和衰减越大。 | Meysam TOOZANDEHJANI Farhad OSTOVAN Khairur Rijal JAMALUDIN Astuty AMRIN Khamirul Amin MATORI Ehsan SHAFIEI | 2020 | Transactions of Nonferrous Metals Society of China2020，30，9： | 4 |
| 3 | Pathology of clinical and preclinical Alzheimer’s disease显示文摘 | Dietmar Rudolf Thal Christine von Arnim W. Sue T. Griffin Haruyasu Yamaguchi Robert E. Mrak Johannes Attems Ajeet Rijal Upadhaya | 2013 | European Archives of Psychiatry and Clinical Neuroscience2013，，2： | 2 |
| 4 | Landslide characteristics and its impact on tourism for two roadside towns along the Kathmandu Kyirong Highway显示文摘Frequent landslide events affect the Kathmandu Kyirong Highway(KKH),one of the most strategic Sino-Nepal highways,with multiple social effects.Amongst them,the impacts on local tourism,although being substantial,have not been studied so far.The aim of this research is to analyze the characteristics of such landslides and their influence on road damages and/or blockages as well as on local tourism industry.We analyzed the co-seismic landslides triggered by the Gorkha Earthquake,2015(7.8 Mw),the post-seismic landslides that occurred during the monsoons following the earthquake,as well as landslides which occurred or reactivated in 2018,with relation to the damage that they caused to the highway.High resolution satellite images from 2015 to 2018,and field data were used for the analysis.The Langtang avalanche that locates off the highway was also mapped due to its high impacts on tourism.Between 2015 and 2018,the number of road damaging landslides in the Betrawati-Rasuwagadhi section of KKH(where Dhunche and Syafrubesi towns are located)was 101 in the main track(MT)and 103 in the new track(NT),with respective average density of 1.46/km and 3.63/km.The dominant observed landslide types were debris slides and rock falls.Landslides were mostly concentrated in the locations with the following characteristics:1)having higher elevated area,2)being located with the‘main central thrust’and other lineaments’belts,3)belonging to the Proterozoic lesser Himalayan rocks,4)having a slope gradient of 25°-45°,5)having northern,western and southern slope aspect,6)being subjected to average annual rainfall of higher than 1,000 mm,and 7)having less than 4 km distance from the past earthquake epicenters.The results further indicated that 7 rain-induced and 4 co-and post-seismic landslides have great impact on tourist flows.An impact analysis was also assessed through a door to door questionnaire survey with local hotel operators from Dhunche and Syafrubesi towns(n=29+31).The results reveal that out of six rigorously affected sectors by landslides leading to road blockage,tourism business is the most impacted livelihood sector in these towns.The reduction of visitors in different hotels ranged from 50%-100%in Dhunche and 70%-100%in Syafrubesi for the first year aftermath of the tremor.This is higher than the respective 5%-50%tourist reduction due to raininduced landslides.Using as a reference the base year 2014,the income loss of hotels in both towns was found to be 50%-100%in 2015,20%-100%in 2016,5%-75%in 2017,and similar to 35%in 2018.These results provide insights on the synergic effect of contributing factors for cut slope as well as down slope instability along mountainous motorways and their impact on income sources for local communities. | Susmita DHAKAL CUI Peng Chandra Prasad RIJAL SU Li-jun ZOU Qiang MAVROULI Olga WU Chun-hao | 2020 | Journal of Mountain Science2020，17，8： | 2 |
| 5 | Neutrophil to lymphocyte ratio and cardiovascular diseases : a review 显示文摘 | Bhat T Teli S Rijal J | 2013 | Expert Rev Cardiovasc T- her2013，11，1： | 1 |
| 6 | Ecotourism’s support of biodiversity conservation显示文摘 | BOOKBINDE M P DINERSTEIN E RIJAL A | 1998 | Conservation Biology1998，12，： | 1 |
| 7 | Minimizing radiation and incision in minimally invasive percutaneous plate osteosynthesis (MIPPO) of distal tibial fractures显示文摘 | Rijal L Sagar G Mani K | 2013 | Eur J Orthop Surg Traumato2013，23，3： | 1 |
| 8 | Supracondylar extension type III fracture of the humerus in children: percutaneous cross - pinning 显示文摘 | Rijal KP Pandey BK | 2006 | Kathmandu Univ Med J2006，4，4： | 1 |
| 9 | Ecotourism's support of biodiversity conservation 显示文摘 | Bookbinder M Dinerstein E Rijal A Cauley H Rajouria A | 1998 | Conservation Biology1998，12，6： | 1 |
| 10 | Detection of tubal abnormalities by HSG in nepalese subfertile women显示文摘 | Shrivastava VR Rijal B Shrestha A | 2009 | Nepal Med Coll J2009，11，1： | 1 |
| 11 | The effects of aldosterone antagonists in pa-tients with resistant hypertension : a meta-analysis of randomized and nonran-domized studies显示文摘 | Dahal K Kunwar S Rijal J | 2015 | Am J Hypertens2015，28，11： | 1 |
| 12 | Detection of tubal abnormalities by HSG in nepalese subfertile women显示文摘 | Shrivastava VR Rijal B Shrestha A | 2009 | Nepal Med Coll J2009，11，1： | 1 |
| 13 | Minimizing radiation and incision in minimally invasive percutaneous plate osteosynthesis(MIPPO)of distal tibial fractures 显示文摘 | Rijal L Sagar G Mani K | 2013 | Eur J Orthop Surg Traumato12013，23，3： | 1 |
| 14 | Neutrophil to lymphocyte ratio and cardiovascular diseases : a review 显示文摘 | Bhat T Teli S Rijal J | 2013 | Expert Rev Cardiovase2013，11，1： | 1 |
| 15 | Prognosis of cervical spinal cord injury in correlation with megnetic resonance imaging显示文摘 | Sato T Kokubun S Rijal KP | 1994 | Paraplegia1994，32，： | 1 |
| 16 | Neutrophil to lymphocyte ratio and cardiovascular diseases:a review显示文摘 | Bhat T Teli S Rijal J | 2013 | Expert Rev Cardiovasc Ther2013，11，1： | 1 |
| 17 | Real-Time Frequency Estimation of Complex GMSK Signal of Green Communications Devices显示文摘Parameter estimation of signals of universal software radio peripheral(USRP) devices is crucial to solve the problem of phase offsets of received signals in distributed beamforming. For systems that will utilize the closed loop feedback algorithm where the receiver needs to send the received signal strength(RSS) values periodically to the beamforming node so as to take advantage of energy conservation, the frequency and phase of these signals should be estimated before smoothening by nonlinear filters. This article presents the estimation of the frequency offsets of a Gaussian minimum shift keying(GMSK) signal from N210 USRP devices in real time by using the Radix-2 fast Fourier transform(FFT) algorithm in GNURadio. For these green communications devices, most of the needed hardware parts have been software defined, thereby reducing the supposed energy consumption. The frequency offsets from reference carrier frequencies of 900 MHz and 2.4 GHz are less than 3 kH z each before the estimation, but the average offsets are 45 Hz and 100 Hz after the estimation, respectively. The high offset value experienced with the 2.4 GHz carrier was due to consistent interference from devices on that same frequency. | Umar Suleiman Dauda NikNoordini NikAbdMalik Mazlina Esa Kamaludin Mohd Yusof Mohd Fairus Mohd Yusoff Mohamed Rijal Hamid | 2016 | Journal of Electronic Science and Technology2016，14，2： | 1 |
| 18 | Using results from fieldsurveys to predict the effect of open windows on thermal comfort and energy use in buildings 显示文摘 | Rijal It Tunhy P Humphreys M | 2007 | Energy and Buildings2007，39，7： | 1 |
| 19 | Method for label -free detection of femtogram quantities of biologies in flowing liquid samples 显示文摘 | MARALDO D RIJAL K CAMPBELL G | 2007 | Analytical Chemistry2007，79，7： | 1 |
| 20 | A meta-analysis of the diagnostic performance of the direct agglutination test and rK39 dipstick for visceral leishmaniasis 显示文摘 | Chappuis F Rijal S Soto A et d | 2006 | BMJ2006，333，7571： | 1 |
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