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| 1 | 一种新型的高频半导体量子点单电子泵显示文摘除了直流负电压外,还在浅法刻蚀出的GaAs/AlGaAs量子线上的两个金属指形门上分别叠加两个相位相差π的正弦信号,从而对形成量子点的两个势垒作不等幅调制.在无源漏偏压的情况下,通过周期形成的量子点实现了单电子的搬运.由于新的半导体量子点单电子泵不是依赖库仑阻塞效应通过隧穿进行单电子输运,因此,该器件就不会受到固定隧穿时间引起的低工作频率限制.在1.7K温度下,频率达到3GHz仍然可以观测到量子化电流平台,对应的电流值达到0.5nA量级.这种新器件提供了实现高速度、高精度搬运单电子的另一种可能途径. | 李玲 Kaestner B Blumenthal M D Giblin S Janssen T J B M Pepper M Anderson D Jones G Ritchie D A 高洁 | 2008 | 物理学报2008,57,3: | 4 |
| 2 | Pancreatic cancer serum biomarker PC-594:Diagnostic performance and comparison to CA19-9显示文摘AIM:To investigate serum PC-594 fatty acid levels as a potential biomarker in North American pancreatic cancer(PaC) patients,and to compare its performance to CA19-9.METHODS:Using tandem mass spectrometry,we evaluated serum PC-594 levels from 84 North American patients with confirmed PaC and 99 cancer-free control subjects.We determined CA19-9 levels by ELISA.Significance between Pa C patients and controls,and association with clinical variables was determined by analysis of variance and t-tests.Diagnostic performance was evaluated by receiver-operator characteristic(ROC)curve analysis,and PC-594 correlation with age and CA19-9 determined by regression analysis.RESULTS:Mean PC-594 levels were 3.7 times lower in Pa C patients compared to controls(P < 0.0001).The mean level in PaC patient serum was 0.76 ± 0.07 μmol/L,and the mean level in control subjects was 2.79 ± 0.15 μmol/L.There was no correlation between PC-594 and age,disease stage or gender(P > 0.05).Using 1.25 μmol/L as a PC-594 threshold produced a relative risk(RR) of 9.4(P < 0.0001,95%CI:5.0-17.7).The area under the receiver-operator characteristic curve(ROCAUC) was 0.93(95%CI:0.91-0.95) for PC-594 and 0.85(95%CI:0.82-0.88) for CA19-9.Sensitivity at 90% specificity was 87% for PC-594 and 71% for CA19-9.Six Pa C patients with CA19-9 above 35 U/m L showed normal PC-594 levels,while 24 Pa C patients with normal CA19-9 showed low PC-594 levels.Eighty-five of the 99 control subjects(86%) showed normal levels of both markers.CONCLUSION:PC-594 biomarker levels are significantly reduced in North American Pa C patients,and showed superior diagnostic performance compared to CA19-9. | Shawn A Ritchie Bassirou Chitou Qingan Zheng Dushmanthi Jayasinghe Wei Jin Asuka Mochizuki Dayan B Goodenowe | 2015 | World Journal of Gastroenterology2015,21,21: | 3 |
| 3 | The cornmercial use of conifer rooted cutting in forestry:a world overview显示文摘 | Ritchie G A | 1991 | New Forests1991,5,: | 1 |
| 4 | Absorption spectral slopes and slope ratios as indicators of molecular weight, source and photobleaching of chromophoric dissolved organic matter 显示文摘 | Helms J R Stubbins A Ritchie J D | 2008 | Limnology and Oceanography2008,53,3: | 1 |
| 5 | New DNA markers forpenguins 显示文摘 | Roeder A D Ritchie P A Lambert D M | 2002 | Conservation Genetics2002,3,3: | 1 |
| 6 | Pathogenesis of virulent Newcastle disease in chickens显示文摘 | Cheville N F Riley J Ritchie A E | 1972 | J Am Vet Med Assoc1972,,: | 1 |
| 7 | Human factor IX transgenic sheep produced by transfer of nuclei from transfected fetal fibroblasts显示文摘 | Kind A J Ritchie W A | 1997 | Science1997,278,5346: | 1 |
| 8 | Recent developments and likely ad- vances in lithium-ion batteries显示文摘 | RITCHIE A HOWARD W | 2006 | J Power Sources2006,162,: | 1 |
| 9 | Absorption spectral slopes and slope ratios as indicators of molecular weight, source, and photobleaching of chromophoric dissolved organic matter显示文摘 | Helms J R Stubbins A Ritchie J D | 2008 | Limnol Oceanogr2008,53,: | 1 |
| 10 | First Ordovician vertebrates from the south hemisphere显示文摘 | Ritchie A Gilbert-Tomlinson J | 1977 | Alcheringa1977,1,: | 1 |
| 11 | Electron microscopy of coronavirus-like particles characteristic of turkey bluecomb disease 显示文摘 | Ritchie A E Deshmukh D R Larsen C T | 1973 | Avian Dis1973,17,: | 1 |
| 12 | Terminating eukaryote translation: domainl of release factor eRF1 functions in stop codon recognition显示文摘 | Bertram G Bell H A Ritchie D W | 2000 | RNA2000,,6: | 1 |
| 13 | Root growth and water uptake during water defiit and recovering in water显示文摘 | Asscng S Ritchie J T Smucher A J | 1998 | Plant and Soil1998,201,2: | 1 |
| 14 | External Reinforcement of Concrete Beams Using Fiber Reinforced Plastics显示文摘 | RITCHIE P A THOMAS D A LU L W | 1991 | Structural Journal1991,88,4: | 1 |
| 15 | Recent developments and future prospects for lithium rechargeable batteries 显示文摘 | RITCHIE A G | 2001 | J Power Sources2001,96,: | 1 |
| 16 | Human factor-IX transgenic sheep produced by transfer of nuclei from transfected fetal fibroblaatsp显示文摘 | Schnieke A E Kind A J Ritchie W A | 1997 | Science1997,278,: | 1 |
| 17 | Protonation of CIS-PBO in metanesulfonic acid solutions显示文摘 | Daniel B Roitman Jan McAlister Marc McAdon Ritchie A Wessling | 1994 | Journal of Polymer Science Part B:Polymer Physics1994,7,32: | 1 |
| 18 | An empirical study of association decision processes in convention site selection 显示文摘 | Fortin P A Ritchie J R B | 1977 | Journal of Travel Research1977,15,4: | 1 |
| 19 | Precursor ion scanning for detection and structural characterization of heterogeneous glycopeptide mixtures显示文摘 | RITCHIE M A GILL A C DEERY M J | 2002 | J Am Soc Mass Spectrom2002,13,9: | 1 |
| 20 | Absorption spectral slopes and slope ratios as indicators of molecular weight,source,and photobleaching of chromophoric dissolved organic matter显示文摘 | HELMS J R STUBBINS A RITCHIE J D | 2008 | Limnology and Oceanography2008,53,3: | 1 |