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20篇 您的检索式:作者名="Roberts FH"
    题名 作者 年代 出处 被引量
1A comparision of the posterolateral and anterolateral approaches total hip arthroplasty显示文摘Roberts JM Fu FH Mccalain EJ 1984Clin Orthop1984,187,:1
2Age-associated neuronal atrophy occurs in the primate brain and is reversible by growth factor gene therapy 显示文摘Smith DE Roberts J Gage FH 1999Neurobiology1999,96,10:1
3Direction of orthodontic tooth movements associated with external apical root resorption of them axillary central incisor 显示文摘Robert JP Edward FH 1998Am J Orthod Dentofac Orthop1998,114,:1
4Quercetin mediates pref-erential degradation of oncogenic Ras and causes autophagy in Ha-RAS-transformed human coloncells显示文摘Psahoulia FH Moumtzi S Roberts ML 2007Carcinogenesis2007,28,5:1
5Radioim- munotherapy of breast cancer metastases with ot-particle emitter 225Ac: Comparing Emcacy with 213Bi and 90Y显示文摘Hung Song Robert FH Ravy Vajravelu 2009Cancer Research2009,69,23:1
6A comparison of the dislocated and anterolateral approach to total hip arthroplasty显示文摘Roberts JM Fu FH McClain EJ 1983Clin Orthop1983,187,:1
7Directions of orthodontic tooth movements associated with external apical root resorption of the maxillary central incisor显示文摘Robert JP Edward FH 1998Am J Orthod Dentofac Orthop1998,114,:1
8Major Changes in the 2005 AHA Guidelines for CPR and ECC Reaching the Tipping Point for Change显示文摘Mary FH Vinay MN Robert WH 2005Circulation2005,112,:1
9Quercetin mediates preferential degradation of oncogenic ras and causes autophagy in Ha-RAStransformed human colon cells 显示文摘Psahoulia FH Moumtzi S Roberts ML 2007Carcinogensis2007,28,5:1
10Randomized prospect ive assessor-blin g evaluation of luteinizing hormone dosage and in vitro fertilization outcome显示文摘 Robert FH Benny HA 2001Fertil Steril2001,75,2:1
11Oral anticoagulants and intracranial hemorrhage:Facts and hypotheses显示文摘Robert FH Bradley SB David CA 1995Stroke1995,26,:1
12Quercetin mediates preferential degradation of oncogenic Ras and causes autophagy in Ha-RAS-transformed human colon cells显示文摘Psahoulia FH Moumtzi S Roberts ML Sasazuki T Shirasawa S Pintzas A 2007Carcinogenesis2007,28,5:1
13Quercetin mediates prefer- ential degradation of oncogenic Ras and causes autophagy in Ha-RAS- transformed human colon cells显示文摘Psahoulia FH Moumtzi S Roberts ML 2007Carcinogensis2007,28,5:1
14Review of Haemaphysalis longicornis of Australia, New Zealand, New Caledonia, Fiji,Japan, Korea and Northeastern China and USSR, and its parthenogenetic and bisexual population显示文摘Hoogstraal H Roberts FH Kohls GM 1968J Parasitol1968,54,:1
15Cajal-Retzius cells in the mouse:transcription factors,neurotransmitters,and birthdays suggest a pallial origin显示文摘Robert FH Tina N Chris E 2003Develop Br Res2003,141,12:1
16Cirrhosis-associated hepa-tocellular nodules:correlation of histopathologic and MR imagingfeatures显示文摘Robert FH Diego AA Norbert K 2008Radio Graphics2008,28,3:1
17Cirrhosis-associated hepatocellular nodules:correlation of histopathologic and MR imaging features显示文摘Robert FH Diego AA Norbert K 2008Radio Graphics2008,28,3:1
18A comparison of the pos- terolateral and anterolateral approaches to total hip arthroplasty 显示文摘Roberts JM Fu FH McCIain EJ 1984Clin Orthop Relat Res1984,,187:1
19Cirrhosis-associated hepatocellular nodules: correlation of histopathologic and MR imaging features 显示文摘Robert FH Diego AA Norbert K 2008Radio Graphics2008,28,3:1
20转染外源性白细胞介素6基因增强乳腺癌细胞株MCF-7表达肿瘤相关抗原显示文摘目的 :探索白细胞介素 6 (interleukin 6 ,IL 6 )增强乳腺癌细胞表达乳腺癌抗原 (CA15 3)和癌胚抗原 (CEA)的作用。方法 :将含IL 6蛋白编码顺序1176bpcDNA插入Pci neo哺乳动物表达载体。将重组载体转染MCF 7乳腺癌细胞 ,采用ELASA方法测定细胞培养上清液内IL 6浓度 ,用MEIA(microp articalenzymeimmunoassay)方法测定上清液中肿瘤相关抗原CA15 3、CEA和CA12 5。结果 :含有外源IL 6基因的MCF 7细胞分泌IL 6浓度 (338.5±2 2 .6pg·10 -6细胞 )明显高于父本没有含外源基因的MCF 7细胞 (2 5 .4± 4 .6pg·10 -6细胞 )和仅含空载体Pci neo的MCF 7细胞 (19.6± 3.0pg·10 -6细胞 ) (P<0 .0 1)。细胞培养d 3后 ,带外源IL 6基因的MCF 7细胞培养上清液中CA15 3和CA12 5水平 (分别为 14 .9± 2 .3和 38.8± 5 .1μg·10 -6细胞 )明显高于父本 (分别为 6 .6± 1.5和 10 .0± 1.6 μg·10 -6细胞 )和空载体Pci neo的MCF 7细胞 (分别为 3.4±0 .7和 14 .6± 2 .2 μg·10 -6细胞 ,P <0 .0 5 )。而转染IL 6基因没有明显改变CEA表达 (P >0 .0 5 )。结论 :IL 6具有诱导肿瘤相关抗原的表达和增强肿瘤细胞的免疫原性的作用 ,提示IL 6可能增强机体对肿瘤的免疫反应性。陈方正 江贤鹏 陈淼 Jonathan FH Robert LE 姜希凌 李欣燕 2004中国临床药理学与治疗学2004,9,12:0
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