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7篇 您的检索式:作者名="Robin Jordan"
    题名 作者 年代 出处 被引量
1Assessment of herbal medicinal products: Challenges, and opportunities to increase the knowledge base for safety assessment显示文摘Scott A. Jordan David G. Cunningham Robin J. Marles 2009Toxicology and Applied Pharmacology2009,,2:2
2Lead absorption and renal dysfunction in a South African battery factory显示文摘Ehrlich R Robins T Jordan E 1998Occup Environ Med1998,55,:1
3Sunitinib Plus Paclitaxel in Patients with Advanced Esophageal Cancer: A Phase II Study from the Hoosier Oncology Groupe显示文摘Jordan M. Schmitt Scott R. Sommers William Fisher Rafat Ansari Erwin Robin Karuna Koneru John McClean Ziyue Liu Yan Tong Nasser Hanna 2012Journal of Thoracic Oncology2012,,4:1
4The Condence to Practice Midwifery: Preceptor Influence on Student Self - Efficacy 显示文摘Robin Jordan Cn M Ph D 2008Journal of Midwifery & Women''s Health2008,53,5:1
5Assessment of herbal medicinal products: Challenges, and opportunities to increase the knowledge base for safety assessment显示文摘Scott A. Jordan David G. Cunningham Robin J. Marles 2009Toxicology and Applied Pharmacology2009,,2:1
6Declining social support in adolescents prior to first episode psychosis: Associations with negative and affective symptoms显示文摘Jordan Edgar DeVylder Robin Edward Gearing 2013Psychiatry Research2013,,:1
7Immature and mature antibodies as defenders against cancer显示文摘Antibodies(Abs)are glycoprotein molecules that represent an essential component of the adaptative immune response.They are secreted in body fluids and act as a critical part of immune defense.Although recognition of self-antigens by Abs is normally selected against during B-cell development,autoreactive Abs can be generated as a result of pathological immune responses,as observed in autoimmune diseases.Autoantibodies can also be produced in cancer patients,where they may have beneficial roles[1].Indeed,the presence of intratumoral antibody-secreting cells(ASCs)and B-cell-rich tertiary lymphoid structures(TLSs)has been observed in many cancer types and generally correlates with a favorable clinical prognosis[2,3,4,5,6].The existence of specific antitumor antibody responses suggests that tumor cells express molecules that are recognized as nonself antigens by the immune system or that tolerance of self-antigens expressed on cancer cells is lost[1,4].The study of the origin of tumor-reactive Abs and their specificity and functions is of paramount importance for understanding the development of adaptive antitumor immune responses and for revealing novel therapeutic avenues.A recent publication in Cell by Mazor et al.[7]has provided an important advance in our understanding of antibody responses in cancer.In particular,this work paves the way for the distinction between antibody-reactive tumors and antibody-nonreactive tumors,which is reminiscent of the dichotomy of the noninfiltrated“cold”tumor microenvironment(TME)in contrast with the highly infiltrated with immune cells“hot”TME[8].Moreover,an important finding of the study was the demonstration that tumor-directed autoreactivity may be either preexisting or induced by somatic hypermutations,a mechanism related to the chronicity of cancer.Robin V.Lacombe Sophie Sibéril Jordan D.Dimitrov 2023Cellular & Molecular Immunology2023,20,1:0
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