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16篇 您的检索式:作者名="Rodrigues CO"
    题名 作者 年代 出处 被引量
1血浆游离DNA水平增高可作为预测重型颅脑损伤患者死亡率的独立指标(英文)显示文摘Trauma is the leading cause of death under 45 years worldwide and up to 50% of trauma fatalities are due to brain injury.Prediction of outcome is one of the major problems associated with severe TBI and research efforts have focused on the investigation of biomarkers with prognostic value following TBI. Therefore,our aim was to investigate whether cell-free DNA concentrations correlated to short-term primary outcome( survivor or death) and GCS scores following severe TBI. A total of 188 victims of severe TBI were enrolled in this prospective study,outcome variables comprised: survival and neurological assessment using the GCS at ICU discharge. Control blood samples were obtained from 25 healthy volunteers. Peripheral venous blood was collected at admission in the ICU. Plasma DNA was measured using a real-time quantitative PCR assay for the β-globin gene. There was correlation between higher DNA levels and both fatal outcome and lower hospital admission GCS scores. Plasma DNA concentrations at the chosen cut- off point( ≥171,381 kilogenomesequivalents /L) predicted mortality with a specificity of 90% and a sensitivity of 43%. Logistic regression analysis showed that elevated plasma DNA levels were independently associated with death( P < 0. 001). In conclusion,high cell-free DNA concentration was a predictor of short-term mortality following severe TBI.Rodrigues Filho EM1 Simon D Ikuta N Klovan C Dannebrock F de Oliveira CO Regner A 2014中华神经外科疾病研究杂志2014,13,3:6
2Regulatory volume de- crease in Trypanosoma cruzi involves amino acid efflux and changes in intracellular calcium 显示文摘Rohloff P Rodrigues CO Docampo R 2003Mol Biochem Parasitol2003,126,2:1
3Rapid changes in polyphos- phate content within acidocaleisomes in response to cell growth, differentiation, and environmental stress in Trypanoso- ma cruzi显示文摘Ruiz FA Rodrigues CO Doeampo R 2001J Biol Chem2001,276,26:1
4Chronic unpre- dictable stress induces a cognitive deficit and anxiety-like behav- ior in rats that is prevented by chronic antidepressant drug treat- ment显示文摘Bondi CO Rodrigues G Gould GG 2008Neuropsychopharmacology2008,33,2:1
5Heterogeneity in SDF-1 expression defines the vasculogenic potential of adult cardiac progenitor cells显示文摘Rodrigues CO Shehadeh LA Hoosien M 2011Plos one2011,6,24:1
6Myocyte deficiency as a target in the treatment of cardiomyopathy 显示文摘Rodrigues CO Shehadeh LA Webster KA 2007Prog Pediatr Cardiol2007,24,:1
7Sputum cytokine levels in patients with pulmonary tuberculosis as early markers of mycobacterial clearance显示文摘RIBEIRO RODRIGUES R RESENDE CO T JOHNSON J L 2002Clin Diagn Lab Immunol2002,9,4:1
8Characterization of complex networks: A survey of measurements 显示文摘Co sta L da F Rodrigues F A Travieso G 2007Adv Phys2007,56,1:1
9A role for CD4^ + CD25 ^+ T cells in regulation of the immune response during human tuberculosis显示文摘RIBEIRO RODRIGUES R RESENDE CO T ROJAS R 2006Clin Exp Immunol2006,144,:1
10A role for CD4+CD25+ T cells in regulation of the immune response during human tuberculosis显示文摘R.Ribeiro‐Rodrigues T.Resende Co R.Rojas Z.Toossi R.Dietze W. H.Boom E.Maciel C. S.Hirsch 2006Clinical & Experimental Immunology2006,,1:1
11inner nuclear mem- brane localization of epidermal growth factor receptor (EGFR) in spontaneous canine model of invasive micropapillary carcinoma of the mammary gland显示文摘Rodrigues MA Gamba CO Faria JA 2016Pathol Res Pract2016,212,4:1
12Presence of a vac- uolar H-pyrophosphatase in promastigotes of Leishnumia donov- niand its localization to a different compartment from the vacuo- lar H-ATPase显示文摘Rodrigues CO Scott DA Docampo R 1999J Biol Chem1999,340,3:1
13Myocyte deficiency as a target in the treatment of cardiomyopathy 显示文摘Rodrigues CO Shehadeh LA Webster KA 2007Prog Pediatr Cardiol2007,23,:1
14Jun kinase delays caspase-9activation by interaction with the apoptosome 显示文摘Tran TH Andreka P Rodrigues CO 2007J Biol Chem2007,282,20:1
15Presence of a Na (+)/H (+) exchanger in acidocalcisomes of Leishmania dono- vani and their alkalization by anti-leishmanial drugs显示文摘Vercesi AE Rodrigues CO Catisti R 2000FEBS Lett2000,473,2:1
16Magic-angle spin- ning (31)P NMR spectroscopy of condensed phosphates in parasitic protozoa: visualizing the invisible 显示文摘Moreno B Rodrigues CO Bailey BN 2002FEBS Lett2002,523,13:1
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