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14篇 您的检索式：作者名="Roelof JM"

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		题名	作者	年代	出处	被引量
	1	Cyclooxygenase-2 polymorphisms and the risk of esophageal adeno-or squamous cell carcinoma显示文摘AIM:To determine whether-1195 A→G and/or-765 G→C polymorphisms in Cyclooxygenase-2(COX-2 ) may have a risk modifying effect on the development of esophageal carcinoma in a Dutch Caucasian population.METHODS:Two study groups were recruited, 252 patients with esophageal carcinoma and 240 healthy controls, matched for race, age, gender and recruiting area.DNA was isolated from whole blood and used for genotyping.PCR products were digested with restriction enzymes and products were analyzed by agarose gel electrophoresis.Odds ratios(OR) and 95% confldence intervals(CI) were estimated.RESULTS:The distribution of the-1195 A→G polymorphism was signif icantly different in esophageal cancer patients compared to controls.The-1195 GG genotype resulted in a higher risk of developing esophageal adenocarcinoma(OR = 3.85, 95% CI:1.45-10.3) compared with the-1195 AA genotype as a reference.The-765 G→C genotype distribution was not different between the two groups.The GG/ GG haplotype was present more often in esophageal adenocarcinoma patients than in controls(OR = 3.45, 95% CI:1.24-9.58;with AG/AG as a reference).The same trends were observed in patients with squamous cell carcinomas, however, the results did not reach statistical signif icance.CONCLUSION:Presence of the COX-2-1195 GG genotype and of the GG/GG haplotype may result in a higher risk of developing esophageal carcinoma.	Jón O Kristinsson Paul van Westerveld Rene HM te Morsche Hennie MJ Roelofs T Wobbes Ben JM Witteman Adriaan CITL Tan Martijn GH van Oijen Jan BMJ Jansen Wilbert HM Peters	2009	World Journal of Gastroenterology2009，15，28：	11
	2	Effects of intraduodenal bile oninterdigestive gastrointestinal and gallbladder motility in healthy subjects显示文摘	Luiking YC Kloppers NJ Roelofs JM	2001	Digestion2001，63，3：	1
	3	The symptom-association probability: an improved method for symptom analysis of 24-hour esophageal pH data 显示文摘	Weusten BL Roelofs JM Akkermans LM	1994	Gastroenterology1994，107，6：	1
	4	Responses to gastric distention in functional dyspepsia显示文摘	Alet GA Samsom M Roelofs JM Smout A J	1998	Gut1998，42，：	1
	5	Compliance of the proximal stomach and dyspeptic symptoms in patients with type Ⅰ diabetes mellitus显示文摘	Salet GA Roelofs JM	1995	Dig Dis Sci1995，40，9：	1
	6	A proteomics approach to understanding protein ubiquitination显示文摘	Peng JM Schwartz D Elias JE Thoreen CC Cheng DM Marsischky G Roelofs J Finley D Gygi SP		0，，08：	1
	7	The symptom association probability : an improved method for symptom analysis of 24-hour esophageal pH data 显示文摘	Weusten BL Roelofs JM Akkermans LM	1994	Gastroenterology1994，107，：	1
	8	Function of the proximal stomach after Nissen fimdoplication显示文摘	Wijnhoven BP Salet GA Roelofs JM	1998	Br J Surg1998，85，：	1
	9	Thyroid Function and bone turnover显示文摘	Bijlsma JW Duursma SA Roelofs JM	1983	Acta Endocrinol (Copenh)1983，104，1：	1
	10	Responses to gastric distension in functional dyspepsia 显示文摘	Salet GA Samsom M Roelofs JM	1998	Gut1998，42，：	1
	11	Effects of intraduode- nal bile on interdigestive gastrointestinal and gallbladder motility in healthy subjects显示文摘	Luiking YC Kloppers NJ Roelofs JM	2001	Digestion2001，63，3：	1
	12	Effects of intraduodenal bile on interdigestive gastrointestinal and gallbladder motility in healthy subjects显示文摘	Luiking YC Kloppers NJ Roelofs JM	2001	Digestion2001，63，3：	1
	13	Tonic motor activity of the narrow gastric tube used as an oesophageal substitute显示文摘	Logeman F Roelof JM Obertop H	2000	Eur J Surg2000，166，：	1
	14	Tonic motor activity of the narrow gastric tube used as an oesophageal substitute显示文摘	Logeman F Roelofs JM Obertop H	2000	Eur J Surg2000，166，4：	1

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