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28篇 您的检索式：作者名="Rogler L"

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	题名	作者	年代	出处	被引量
1	Mucosal healing and deep remission: What does it mean?显示文摘The use of specific terms under different meanings and varying definitions has always been a source of confusion in science.When we point our efforts towards an evidence based medicine for inflammatory bowel diseases(IBD)the same is true:Terms such as'mucosal healing'or'deep remission'as endpoints in clinical trials or treatment goals in daily patient care may contribute to misconceptions if meanings change over time or definitions are altered.It appears to be useful to first have a look at the development of terms and their definitions,to assess their intrinsic and context-independent problems and then to analyze the different relevance in present-day clinical studies and trials.The purpose of such an attempt would be to gain clearer insights into the true impact of the clinical findings behind the terms.It may also lead to a better defined use of those terms for future studies.The terms'mucosal healing'and'deep remission'have been introduced in recent years as new therapeutic targets in the treatment of IBD patients.Several clinical trials,cohort studies or inception cohorts provided data that the long term disease course is better,when mucosal healing is achieved.However,it is still unclear whether continued or increased therapeutic measures will aid or improve mucosal healing for patients in clinical remission.Clinical trials are under way to answer this question.Attention should be paid to clearly address what levels of IBD activity are looked at.In the present review article authors aim to summarize the current evidence available on mucosal healing and deep remission and try to highlight their value and position in the everyday decision making for gastroenterologists.	Gerhard Rogler Stephan Vavricka Alain Schoepfer Peter L Lakatos	2013	World Journal of Gastroenterology2013，19，43：	4
2	MicroRNA-23b cluster microRNAs regulate transforming growth factor-beta/bone morphogenetic protein sig-naling and liver stem cell differentiation by targeting Smads 显示文摘	Rogler CE Levoci L Ader T	2009	Hepatology2009，50，2：	1
3	Genomic expression analysis implicates Wnt signaling pathway and extracellular matrix alterations in hepatic specification and differentiation of murine hepatic stem cells显示文摘	Plescia C Rogler C Rogler L	2001	Differentiation2001，68，25：	1
4	Reactivation of the maternally imprinted IGF-2 allele in TGF alpha induced hepatoeellular carcinomas in mice显示文摘	Harris T M Rogler L E Rogler C E	1999	Oncogene1999，16，2：	1
5	The effects of dietary aspirin and humidity on the performance of light and heavy breed chicks显示文摘	ADAMS R L ROGLER J C	1968	Poultry Science1968，47，4：	1
6	Targeted disruption of IGFBP-2 gene显示文摘	Wood TL Rogler L Streck RD	1993	Growth Regulation1993，8，：	1
7	Marital heterogamy and marital quality in Puerto Rican families 显示文摘	Rogler L H Procidano M E	1989	Journal of Marriage and the Family1989，，：	1
8	Genomic expression analysis implicates Wnt signaling pathway and extracellular matrix alterations in hepatic specification and differentiation of murine hepatic stem ceils显示文摘	Plescia C Rogler C Rogler L	2001	Differentiation2001，68，：	1
9	The intestinal microbiota:its role in health and disease显示文摘	Biedermann L Rogler G	2015	Eur J Pediatr2015，174，2：	1
10	Methodological sources of cultural insensitivity in mental health research显示文摘		1999	American Psychologist1999，54，6：	1
11	Absorption and distribution of 14C-labeled condensed tannins and related sorghum phenolics in chickens显示文摘	ROGLER J C HOUSLEY T L	1994	Journal of Agricultural and Food Chemistry1994，42，：	1
12	Altered body composition and increased frequency of diverse malignancies in insulin-like growth factor 2 transgenic mice显示文摘	Rogler CE Yang D Rossetti L	1994	J Biol Chem1994，26，13：	1
13	Genomic expression analysis implicates Wnt signaling pathway and extracellular matrix alterations in hepatic specification and differentiation of murine hepatic stem cells显示文摘	Plescia C Rogler C Rogler L	2001	Differentiation2001，68，：	1
14	Selective alterations in qrgan sizes in mice with a targeted disruption of the insulin-like growth factor binding protein-2 Gene 显示文摘	Wood T L Rogler L E Czick M E et ol	2001	Mol Endocrinol2001，14，9：	1
15	Genomic expression analysis implicates Wnt signaling pathway and extracellular matrix alterations in hepatic specification and differentiation of murine hepatic stem cells显示文摘	Plescia C Rogler C Rogler L	2001	Differentiation2001，68，45：	1
16	Altered body composition and increased frequency of diverse malignancies in insulin-like growth factor 2 transgenic mice显示文摘	Rogler CE Yang D Rossetti L	1994	J Biol Chem1994，269，13：	1
17	Physical modeling of inclusion removal in a tundish by gas bubbling显示文摘	Rogler J P Heaslip L J Mehrvar M	2005	Canadian Metall Quart2005，45，3：	1
18	Genomic expression analysis implicates Wnt signaling pathway and extracellular matrix alterations in hepatic specification and differentiation of murine hepatic stem cells显示文摘	Plescia C Rogler C Rogler L	2001	Differentiation2001，68，：	1
19	Identification of hepatocytic and bile duetular cell lineages and candidate stem cells in bipolar duetular reactions in cirrhotic human liver显示文摘	Zhou HC Rogler LE Teperman L	2007	Hepatology2007，45，3：	1
20	Altered body composition and increased frequency of diverse malignancies in insulin-like growth factor 2 transgen- ic mice 显示文摘	Rogler CE Yang D Rossetti L	1994	J Biol Chem1994，26，13：	1

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