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| 1 | Prognostic value of increased carbohydrate antigen in patients with heart failure显示文摘AIM:To study the prognostic value of carbohydrateantigen 125(CA125) and whether it adds prognostic information to N-terminal pro-brain natriuretic peptide(NT-proBNP) in stable heart failure(HF) patients.METHODS:The predictive value of CA125 was retrospectively assessed in 156 patients with stable HF remitted to the outpatient HF unit for monitoring from 2009 to 2011.Patients were included in the study if they had a previous documented episode of HF and received HF treatment.CA125 and NT-proBNP concentrations were measured.The independent association between NT-proBNP or CA125 and mortality was assessed with Cox regression analysis,and their combined predictive ability was tested by the integrated discrimination improvement(IDI) index.RESULTS:The mean age of the 156 patients was 72 ± 12 years.During follow-up(17 ± 8 mo),27 patients died,1 received an urgent heart transplantation and 106 required hospitalization for HF.Higher CA125 values were correlated with outcomes:58 ± 85 KU/L if hospitalized vs 34 ± 61 KU/L if not(P < 0.05),and 94 ± 121 KU/L in those who died or needed urgent heart transplantation vs 45 ± 78 KU/L in survivors(P < 0.01).After adjusting for propensity scores,the highest risk was observed when both biomarkers were elevated vs not elevated(HR = 8.95,95%CI:3.11-25.73; P < 0.001) and intermediate when only NT-proBNP was elevated vs not elevated(HR = 4.15,95%CI:1.41-12.24; P < 0.01).Moreover,when CA125 was added to the clinical model with NT-proBNP,a 4%(P < 0.05) improvement in the IDI was found.CONCLUSION:CA125 > 60 KU/L identified patients in stable HF with poor survival.Circulating CA125 level adds prognostic value to NT-proBNP level in predicting HF outcomes. | Ana B Méndez Jordi Ordonez-Llanos Andreu Ferrero Mariana Noguero Teresa Mir Josefina Mora Antoni Bayes-Genis Sònia Mirabet Juan Cinca Eulàlia Roig | 2014 | World Journal of Cardiology2014，6，4： | 13 |
| 2 | Minimally invasive versus open oesophagectomy for patients with oesophageal cancer: a multicentre, open-label, randomised controlled trial显示文摘 | Surya SAY Biere Mark I van Berge Henegouwen Kirsten W Maas Luigi Bonavina Camiel Rosman Josep Roig Garcia Suzanne S Gisbertz Jean HG Klinkenbijl Markus W Hollmann Elly SM de Lange H Jaap Bonjer Donald L van der Peet Miguel A Cuesta | 2012 | The Lancet . 2012 (9829)2012，，： | 3 |
| 3 | Reduction of counts ofListeria monocytogenes in cheese by means of high hydro-static pressure 显示文摘 | L6pez P T Roig S A De L S | 2007 | Food Microbiology2007，24，1： | 1 |
| 4 | Minimally invasive versus open oesophagectomy for patients with oesophageal cancer: a multicentre, open-label, randomised controlled trial显示文摘 | Surya SAY Biere Mark I van Berge Henegouwen Kirsten W Maas Luigi Bonavina Camiel Rosman Josep Roig Garcia Suzanne S Gisbertz Jean HG Klinkenbijl Markus W Hollmann Elly SM de Lange H Jaap Bonjer Donald L van der Peet Miguel A Cuesta | 2012 | The Lancet2012，，9829： | 1 |
| 5 | Lateral punch-through TVS devices for on- chip protection in low-voltage applications显示文摘 | URRESTI J HIDALGO S FLORES D ROIG J CORTE' s I REBOLL J | 2005 | Microelec- tronics Reliability2005，45，6： | 1 |
| 6 | Studies on the occurrence of non-enzymatic browning during storage of citrus juice显示文摘 | Roig M G Bello J F Rivera Z S | 1999 | Food Research International1999，32，9： | 1 |
| 7 | A linear regression model using triangular fuzzy number coefficients显示文摘 | Yen K K Ghoshray S Roig G | 1999 | Fuzzy Sets and Systems1999，，106： | 1 |
| 8 | Invasive cervical resorption:report on two cases显示文摘 | Roig M MorellóS MercadéM | 2010 | Oral Surg Oral Med Oral Pathol Oral Radiol End2010，110，4： | 1 |
| 9 | Changes in the cooling rate and medium improve the vascular function in cryopreserved porcine femoral arteries显示文摘 | Montserrat Rigol Magda Heras Anna Martínez María Jesús Zurbano Elba Agustí Eulàlia Roig José Luís Pomar Ginés Sanz | 2000 | Journal of Vascular Surgery2000，，5： | 1 |
| 10 | Studies on the occurrence of non-enzymatic browning during storage of citrus juice显示文摘 | Roig M G Bello J F Rivera Z S | 1999 | Food Research International1999，32，9： | 1 |
| 11 | Contribution of the lignocellulosic fraction of two-phase olive-mill wastes to the degradation and humification of the organic matter during composting显示文摘 | Serrami~ N S~achez-Monedero MA Femkqdez-Hem~ndez A Garcia-Ortiz CC Roig A | 2010 | Waste Management2010，30，10： | 1 |
| 12 | Prog- nostic value of the detection of lymph node micrometastases in co- lon cancer显示文摘 | Bosch Roig CE Rosello SE Alonso Hernandez S el al | 2008 | Clin Transl Oncol2008，10，9： | 1 |
| 13 | Nitrogen transformation during organic waste composting by the Rutgers system and its effects on pH,EC and maturity of the composting mixtures显示文摘 | Sánchez-Monedero M A Roig A Paredes C | 2001 | Bioresource Technology2001，78，3： | 1 |
| 14 | Studies on the occurrence of non-enzymatic browning during storage of citrus juice显示文摘 | Roig M G Bello J F Riera Z S | 1999 | Food Res Int1999，32，9： | 1 |
| 15 | Biogenic amines in Finnish dry sausages显示文摘 | EEROLA H S ROIG SAGUt:S A X HIRVI T K | 2007 | Journal of Food Safety2007，18，2： | 1 |
| 16 | The New Venture Decision:An A-nalysis Based on the GEM Project Database显示文摘 | Morales-Gualdron S T Roig S | 2005 | International Entre-preneurship and Management Journal2005，，47： | 1 |
| 17 | Use of biochar as bulking agent for the composting of poultry manure:Effect on organic matter degradation and humification显示文摘 | Dias B.O Silva C.A Higashikawa F.S Roig A SánchezMonedero M.A | | 0，，： | 1 |
| 18 | Studies on the occurrence of non-enzymatic browning during storage of citrus juice显示文摘 | Roig M G Bello J F Rivera Z S | 1999 | Food Research International1999，32，9： | 1 |
| 19 | Customer perceivedvalue in banking services 显示文摘 | Roig J C F Garcia J S Tena M A M | 2006 | International Journal of Bank Marketing2006，24，5： | 1 |
| 20 | Studies on the occurrence of non-enzymatic browning during storage of citrus juice显示文摘 | Roig M G Bello J F Riera Z S | 1999 | Food res Int1999，32，： | 1 |
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