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| 1 | A randomized open-label trial of on-demand rabeprazole vs ranitidine for patients with non-erosive reflux disease显示文摘AIM:To compare the efficacy of the proton-pump inhibitor,rabeprazole,with that of the H 2-receptor antagonist,ranitidine,as on-demand therapy for relieving symptoms associated with non-erosive reflux disease(NERD).METHODS:This is a single center,prospective,randomized,open-label trial of on-demand therapy with rabeprazole(group A) vs ranitidine(group B) for 4 wk.Eighty-three patients who presented to the American University of Beirut Medical Center with persistent gastroesophageal reflux disease(GERD) symptoms and a normal upper gastrointestinal endoscopy were eligible for the study.Patients in group A(n = 44) were allowed a maximum rabeprazole dose of 20 mg twice daily,while those in group B(n = 39) were allowed a maximum ranitidine dose of 300 mg twice daily.Efficacy was assessed by patient evaluation of global symptom relief,scores of the SF-36 quality of life(QoL) questionnaires,total number of pills used,and number of medication-free days.RESULTS:Among the 83 patients who were enrolled in the study,76 patients(40 in the rabeprazole group and 36 in the ranitidine group) completed the 4-wk trial.Baseline characteristics were comparable between both groups.After 4 wk,there was no significant difference in the subjective global symptom relief between the rabeprazole and the ranitidine groups(71.4% vs 65.4%,respectively;P = 0.9).There were no statistically significant differences between mean cumulative scores of the SF-36 QoL questionnaire for the two study groups(rabeprazole 22.40 ± 27.53 vs ranitidine 17.28 ± 37.06;P = 0.582).There was no significant difference in the mean number of pills used(rabeprazole 35.70 ± 29.75 vs ranitidine 32.86 ± 26.98;P = 0.66).There was also no statistically significant difference in the mean number of medication-free days between both groups.CONCLUSION:Rabeprazole has a comparable efficacy compared to ranitidine when given on-demand for the treatment of NERD.Both medications were associated with improved quality of life. | Abdallah A Kobeissy Jana G Hashash Faek R Jamali Assaad M Skoury Reham Haddad Sarah El-Samad Rami Ladki Rola Aswad Assaad M Soweid | 2012 | World Journal of Gastroenterology2012，18，19： | 4 |
| 2 | Posterior lingual lidocaine: A novel method to improve tolerance in upper gastrointestinal endoscopy显示文摘AIM: To evaluate the effect of posterior lingual lidocaine swab on patient tolerance to esophagogastro-duodenoscopy, the ease of performance of the procedure, and to determine if such use will reduce the need for intravenous sedation. METHODS: Eighty patients undergoing diagnostic esophagogastroduodenoscopy in a tertiary care medical center were randomized to either lidocaine swab or spray. Intravenous meperidine and midazolam were given as needed during the procedure. RESULTS: Patients in the lidocaine swab group (SWG) tolerated the procedure better than those in the spray group (SPG) with a median tolerability score of 2 (1, 4) compared to 4 (2, 5) (P < 0.01). The endoscopists encountered less diffi culty performing the proceduresin the SWG with lower median difficulty scores of 1 (1, 5) compared to 4 (1, 5) in the SPG (P < 0.01). In addition, the need for intravenous sedation was also lower in the SWG compared to the SPG with fewer patients requiring intravenous sedation (13/40 patients vs 38/40 patients, respectively, P < 0.01). The patients in the SWG were more satisfi ed with the mode of local anesthesia they received as compared to the SPG. In addition, the endoscopists were happier with the use of lidocaine swab. CONCLUSION: The use of a posterior lingual lidocaine swab in esophagogastroduodenoscopy improves patient comfort and tolerance and endoscopist satisfaction and decreases the need for intravenous sedation. | Assaad M Soweid Shadi R Yaghi Faek R Jamali Abdallah A Kobeissy Michella E Mallat Rola Hussein Chakib M Ayoub | 2011 | World Journal of Gastroenterology2011，17，47： | 2 |
| 3 | Specificity and nucleo- typing studies of a gp50 based polymerase chain reaction assay for detection of pseudorabies vires 显示文摘 | Harding M J Prudhomme I Rola J | 1997 | Can J Vet Res1997，61，2： | 1 |
| 4 | Roles of the mammalian subventricular zone in cell replacement after brain injury显示文摘 | Romanko M J Rola R Fike JR | 2004 | Prog Neurobiol2004，74，2： | 1 |
| 5 | Differentiation of vascular tumorsfrom vascular malformations by expression of Wilms tumor 1 gene: Eval-uation of 126 cases显示文摘 | Rola AD Julie P Catherine M | 2010 | J AM ACAD DERMATOL2010，63，6： | 1 |
| 6 | Effect of an occlusal screw-access hole on the fracture resistance of permanently cemented implant crowns: alaboratory study 显示文摘 | Shadid Rola M | | Int J Prosthodont0，243，： | 1 |
| 7 | Glass fibre aggregates:consequences on the dynamic mechanical properties of polypropylene matrix composites显示文摘 | M(A)(A)l(A)(A) P Alb(A)(A)rola N D | 2005 | Composites Science and Technology2005，65，34： | 1 |
| 8 | Characterization and alkaline decomposition-cyanidation of beudantite-jarosite materials from Rio Tinto ores显示文摘 | ROLA A V1NALS J ARRANZ M CALERO J | 1999 | Canadian Metallurgical Quarterly1999，38，2： | 1 |
| 9 | Postoperative Complications After Primary Adult Optical Penetrating Keratoplasty: Prevalence and Impact on Graft Survival显示文摘 | Michael D Wagoner Rola Ba-Abbad Mansour Al-Mohaimeed Samar Al-Swailem M Bridget Zimmerman | 2009 | Cornea2009，，4： | 1 |
| 10 | Kinetics model for the cyanidation of silver ammonium jarosite in NaOH medium显示文摘 | ROLA A CRUELLS M PATINO F RIVERA I PLATA M | 2006 | Hydrometallurgy2006，81，1： | 1 |
| 11 | Use of 16S rRNA gene sequencing to identify lactobacillus casei in Septicaemia Secondary to a Paraprosthetic Enteric Fistula 显示文摘 | PA'ROLA P MAURIN M ALIMI Y | 1998 | European Journal of Clinical Microbiology & Infectious Diseases1998，17，： | 1 |
| 12 | 显示文摘 | Nguer CM Treton D Rola Pleszczynski M | 1996 | Lipids1996，31，10： | 1 |
| 13 | Kinetics of alkaline decomposition and cyanidation of argentian ammonium jarosite in lime medium显示文摘 | PATINO F CRUELLS M ROLA A SALINAS E PEREZ M | 2003 | Hydrometallurgy2003，70，1： | 1 |
| 14 | Cesarean scar ectopie pregnancies : etiology, diagnosis, and management显示文摘 | Rolas MA Haberman S Levgur M | 2006 | Obstet Gynecol2006，107，6： | 1 |
| 15 | VirB12 is a serological marker of Brueella infection in experimental and nat-ural hosts 显示文摘 | Rola'n G H Den Hartigh B A Kahl-McDonagh M | 2008 | Clin Vaccine Immunol2008，15，2： | 1 |
| 16 | High-performance liquid chromatography and capillary electrophoresis: Methodological challenges for the deterruination of biologically relevant low-aliphatic aldehydes in human saliva显示文摘 | ANNOVAZZI L CATTANEO V VIGLIO S PERANI E ROTA C PECORA F CETFA G SILVESTRI M IADA- ROLA P | 2004 | Electrophoresis2004，25，9： | 1 |
| 17 | Specificity and nucleotyping studies of a Gp50 based polymerase chain reaction assay for detection of pseudorabies virus显示文摘 | HARDING M J PRUD HOMME I ROLA J | 1997 | Can J Vet Res1997，61，2： | 1 |
| 18 | Plasma levels of neuropeptides and metabolic hormones,and sleepiness in obstructive sleep apnea显示文摘 | Sánchez-de-la-Torre M Barceló A Piérola J | 2011 | Respir Med2011，105，12： | 1 |
| 19 | Silicon anisotropic etching in TMAH solutions containing alcohol and surfactant additives显示文摘 | ZUBEL I KRAMKOWSKA M ROLA K | | 0，，： | 1 |
| 20 | Kinetics of alkaline decomposition and cyanidation of argentian ammonium jarosite in lime medium显示文摘 | Patino F Cruells M Rola A | 2003 | Hydrometallurgy2003，70，1： | 1 |
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