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| 1 | 血管性认知障碍的诊断标准:国际血管性行为与认知障碍学会的申明显示文摘长期以来,脑血管病(CVD)就被认为是认知损害的一个重要原因,但是有关脑血管病后认知障碍的概念化却有着一段多变的历史。'动脉变硬'或脑的动脉粥样硬化是'老化'的原因,是存在已久的观点,在20世纪60年代受到了来自英格兰纽卡斯尔的神经病理学研究的质疑。这些研究表明,血管性痴呆(vascular dementia,Va D)与超过一定程度的多发性脑梗死有关。 | 徐岩 郭起浩 Sachdev P Kalaria R O'Brien J Skoog I Alladi S Black SE Blacker D Blazer DG Chen C Chui H Ganguli M Jellinger K Jeste DV Pasquier F Paulsen J Prins N Rockwood K Roman G Scheltens P | 2014 | 神经病学与神经康复学杂志2014，11，3： | 19 |
| 2 | Hepatitis C virus genotypes distribution and transmission risk factors in Luxembourg from 1991 to 2006显示文摘AIM:To analyze the Hepatitis C virus (HCV) genotype distribution and transmission risk factors in a population of unselected patients in Luxembourg. METHODS:Epidemiological information (gender, age and transmission risks) were collected from 802 patients newly diagnosed for hepatitis C and living in Luxembourg, among whom 228 patients referred from prison. Genotyping using 5'noncoding (5'NC) sequencing was performed. We compared categorical data using the Fisher's exact F-test and odds ratios (OR) were calculated for evaluating association of HCV genotype and risk factors. RESULTS:The sex ratio was predominantly male (2.2) and individuals aged less than 40 years represented 49.6% of the population. Genotype 1 was predominant (53.4%) followed by genotype 3 (33%). Among risk factors, intravenous drug usage (IVDU) was the most frequently reported (71.4%) followed by medical-related transmission (17.6%) including haemophilia, transfusion recipients and other nosocomial reasons. Genotype 3 was significantly associated to IVDU (OR = 4.84, P < 0.0001) whereas genotype 1 was significantly associated with a medical procedure (OR = 2.42, P < 0.001). The HCV genotype distribution from inmate patients differed significantly from the rest of the population (Chi-square test with four degrees of freedom, P < 0.0001) with a higher frequency of genotype 3 (46.5% vs 27.5%) and a lower frequency of genotype 1 and 4 (44.7% vs 56.8% and 5.3% vs 9.6%, respectively). IVDU was nearly exclusively reported as a risk factor in prison. CONCLUSION:We report the first description of the HCV genotype distribution in Luxembourg. The repartition is similar to other European countries, with one of the highest European prevalence rates of genotype 3 (33%). Since serology screening became available in 1991, IVDU remains the most common way of HCV transmission in Luxembourg. | Francois Roman Karin Hawotte Daniel Struck Anne-Marie Ternes Jean-Yves Servais Vic Arendt Patrick Hoffman Robert Hemmer Thérèse Staub Carole Seguin-Devaux Jean-Claude Schmit | 2008 | World Journal of Gastroenterology2008，14，8： | 3 |
| 3 | Prognostic significance of the pattern of aorta root dilation in the Marfan syndrome显示文摘 | Roman MJ Rosen SE Kramer-Fox R | 1993 | J Am Coil Cardiol1993，22，5： | 1 |
| 4 | The perpetrators of domestic violenee显示文摘 | Romans SE Poore MR Martin JL | 2000 | Med J Aust2000，173，9： | 1 |
| 5 | Prognostic significance of the Pattern of aortic root dilatation in the Marfan syndrome 显示文摘 | Roman M J Rosen SE Kramer- Fox R | 1993 | Am Coil Cardiol1993，22，： | 1 |
| 6 | Randomized, placebo-controlled, clinical trial of donepezil in vascular dementia: differential effects by hippocampal size 显示文摘 | Roman GC Salloway S Black SE | 2010 | Stroke2010，41，6： | 1 |
| 7 | Randomized, placebo- controlled, clinical trial of donepezil in vascular dementia: differ- ential effects by hippocampal size 显示文摘 | Roman GC Salloway S Black SE | 2010 | Stroke2010，41，6： | 1 |
| 8 | Randomized, pla- cebo-con-trolled, clinical trial of donepezil in vascular de- mentia: differential effects by hippocampal size显示文摘 | Roman GC Salloway S Black SE | 2010 | Stroke2010，41，6： | 1 |
| 9 | Becoming the best mom that I can:women′s experiences of managing depression during pregnancy:a qualitative study显示文摘 | Bennett HA Boon HS Romans SE | 2007 | BMC Womens Health2007，7，： | 1 |
| 10 | Psychological defense styles in women who report childhood sexual abuse: a controlled community study 显示文摘 | Romans SE Martin JL Morris E | 1999 | Am J Psychiatry1999，156，7： | 1 |
| 11 | Randomized, place- bo-controlled, clinical trial of donepezil in vascular dementia: differential effects by hippocampal size 显示文摘 | ROMAN GC SALLOWAY S BLACK SE | 2010 | Stroke2010，41，6： | 1 |
| 12 | Roles tor pituitary adeny- late cyclase - activating peptide (PACAP) expression and signaling in the bed nucleus of the stria terminalis(BNST) in mediating the behav- ioral consequences of ehronie stress显示文摘 | Harmnack SE Roman CW Lezak KR | 2010 | J Mol N eumsci2010，42，3： | 1 |
| 13 | Randomized, placebo-con- trolled, clinical trial of donepezil in vascular dementia: differential ef- fects by hippocampal size显示文摘 | Roman GC Salloway S Black SE | 2010 | Stroke2010，41，6： | 1 |
| 14 | Prognostic significance of the Pattern of aortic root dilatation in the Marfan syndrome显示文摘 | Roman MJ Rosen SE Kramer Fox R | 1993 | Am Coil Car- did1993，22，5： | 1 |
| 15 | Randomized, placebo - controlled, clinical trial of donepezil in vascular dementia: dif- ferential effects by hippocampal size 显示文摘 | Roman GC Salloway S Black SE | 2010 | Stroke2010，41，6： | 1 |
| 16 | The perpetrators of domestic violence显示文摘 | Romans SE Poore MR Martin JL | | 0，，9： | 1 |
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