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| 1 | Psychosocial mechanisms for the transmission of somatic symptoms from parents to children显示文摘AIM: To examine familial aggregation of irritable bowel syndrome(IBS) via parental reinforcement/modeling of symptoms, coping, psychological distress, and exposure to stress.METHODS:Mothers of children between the ages of8 and 15 years with and without IBS were identified through the Group Health Cooperative of Puget Sound.Mothers completed questionnaires,including the Child Behavior Checklist(child psychological distress),the Family Inventory of Life Events(family exposure to stress),SCL-90R(mother psychological distress),and the Pain Response Inventory(beliefs about pain).Children were interviewed separately from their parents and completed the Pain Beliefs Questionnaire(beliefs about pain),Pain Response Inventory(coping)and Child Symptom Checklist[gastrointestinal(GI)symptoms].In addition,health care utilization data was obtained from the automated database of Group Health Cooperative.Mothers with IBS(n=207)and their 296 children were compared to 240 control mothers and their 335 children,while controlling for age and education.RESULTS:Hypothesis 1:reinforcement of expression of GI problems is only related to GI symptoms,but not others(cold symptoms)in children.There was no significant correlation between parental reinforcement of symptoms and child expression of GI or other symptoms.Hypothesis 2:modeling of GI symptomsis related to GI but not non-GI symptom reporting in children.Children of parents with IBS reported more non-GI(8.97 vs 6.70,P<0.01)as well as more GI(3.24 vs 2.27,P<0.01)symptoms.Total health care visits made by the mother correlated with visits made by the child(rho=0.35,P<0.001 for cases,rho=0.26,P<0.001 for controls).Hypothesis 3:children learn to share the methods of coping with illness that their mothers exhibit.Methods used by children to cope with stomachaches differed from methods used by their mothers.Only 2/16 scales showed weak but significant correlations(stoicism rho=0.13,P<0.05;acceptance rho=0.13,P<0.05).Hypothesis 4:mothers and children share psychological traits such as anxiety,depression,and somatization.Child psychological distress correlated with mother’s psychological distress(rho=0.41,P<0.001 for cases,rho=0.38,P<0.001 for controls).Hypothesis 5:stress that affects the whole family might explain the similarities between mothers and their children.Family exposure to stress was not a significant predictor of children’s symptom reports.Hypothesis 6:the intergenerational transmission of GI illness behavior may be due to multiple mechanisms.Regression analysis identified multiple independent predictors of the child’s GI complaints,which were similar to the predictors of the child’s non-GI symptoms(mother’s IBS status,child psychological symptoms,child catastrophizing,and child age).CONCLUSION:Multiple factors influence the reporting of children’s gastrointestinal and non-gastrointestinal symptoms.The clustering of illness within families is best understood using a model that incorporates all these factors. | Miranda AL van Tilburg Rona L Levy Lynn S Walker Michael Von Korff Lauren D Feld Michelle Garner Andrew D Feld William E Whitehead | 2015 | World Journal of Gastroenterology2015，21，18： | 2 |
| 2 | Social learning contributions to the etiology and treatment of functional abdominal pain and inflammatory bowel disease in children and adults显示文摘This paper reviews empirical work on cognitive and social learning contributions to the etiology and treatment of illness behavior associated with functional abdominal pain and inflammatory bowel disease. A particular emphasis is placed on randomized controlled trials, the majority of which are multi-modal in orientation, incorporating elements of cognitive behavioral therapy, social learning, and relaxation. Based on this review, we offer methodological and clinical suggestions: (1) Research investigations should include adequate sample sizes, long-term follow-up assessments, and a credible, active control group. (2) Standard gastrointestinal practice should include, when appropriate, learning opportunities for patients and family members, for example, instruction regarding the encouragement of wellness behavior. | Rona L Levy Shelby L Langer William E Whitehead | 2007 | World Journal of Gastroenterology2007，13，17： | 2 |
| 3 | Induction of RAB18 gene expression and activation of K^+ outward rectifying channels depend on an extracellular perception of ABA in Arabidopsis thaliana suspension cells 显示文摘 | Jeannette E Rona J P Bardat F | 2002 | The Plant Journal2002，18，1： | 1 |
| 4 | Expression of osteoclast differentiation factor at sites ofboneerosion in collagen induced arthritis显示文摘 | Ronas E Bakharevski O Hards DK | 2000 | Arthritis Rheum2000，43，4： | 1 |
| 5 | Futterungsversuche mit durchpankreatin, durch pepsinsalzsaure plus pankreatin and durchSaure dydrolysiertem casein 显示文摘 | Rona P | 1904 | Hoppe-Seyler''s Z physiolChem1904，42，： | 1 |
| 6 | The cosmetic treatment of wrinkles显示文摘 | Rona C Vailati F Berardesca E | 2004 | J Cosmet dermatol2004，3，1： | 1 |
| 7 | Induction of RAB18 gene expression and activation of K+ outward rectifying channels depend on an extracellular perception of ABA in Arabidopsis thaliana suspension cells显示文摘 | Jeannette E Rona JP Bardat F | 1999 | Plant J1999，18，1： | 1 |
| 8 | Thermal properties of TAG hydrothermal precipitates, Mid Atlantic Ridge, and comparison with Middle Valley, Juan de Fuca Ridge显示文摘 | RONA P A DAVIS E E LUDWlNG R J | 1998 | Proc ODP Sci Results1998，158，： | 1 |
| 9 | The cosmetic treatment of wrinkles显示文摘 | RONA C VAILATI F BERARDESCA E | 2004 | Journal of Cosmetic Dermatology2004，3，1： | 1 |
| 10 | Detection of a chromosomal region with two quantitative trait loci,affecting cold tolerance and fish size,in an F2 tilapia hybrid显示文摘 | Cnaani A Hallerman E M Rona M | 2003 | Aquaculture2003，223，： | 1 |
| 11 | Magnetic prop- erties and opaque mineralogy of rocks from selected seafloor hy- drothermal sites at oceanic ridges显示文摘 | Wooldridge A L Haggerty S E Rona P A | 1990 | Journal of Geophysical Re- search1990，95，12： | 1 |
| 12 | The use of a capacitance device to evaluate the hydration of human skin显示文摘 | Zuang V Rona C Distante F Beradesca E | 1997 | J Appl Cosmetol1997，15，： | 1 |
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