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| 1 | Characteristics of Clostridium difficile infection in patients hospitalized with myelodysplastic syndrome or acute myelogenous leukemia显示文摘AIM To evaluate factors associated with Clostridium difficile infection (CDI) and outcomes of CDI in the myelodysplastic syndrome(MDS) and acute myeloid leukemia (AML) population.METHODS After IRB approval,all MDS/AML patients hospitalized at the University of Maryland Greenebaum Comprehensive Cancer Center between August 2011 and December 2013 were identified.Medical charts were reviewed for demographics,clinical information,development of CDI,complications of CDI,and mortality.Patients with CDI,defined as having a positive stool PCR done for clinical suspicion of CDI,were compared to those without CDI in order to identify predictors of disease.A t-test was used for comparison of continuous variables and chisquare or Fisher's exact tests were used for categorical variables,as appropriate.RESULTS Two hundred and twenty-three patients (60.1% male,mean age 61.3 years,13% MDS,87% AML) had 594 unique hospitalizations during the study period.Thirtyfour patients (15.2%) were diagnosed with CDI.Factors significantly associated with CDI included lower albumin at time of hospitalization (P < 0.0001),prior diagnosis of CDI (P < 0.0001),receipt of cytarabine-based chemotherapy (P = 0.015),total days of neutropenia (P = 0.014),and total days of hospitalization (P = 0.005).Gender (P = 0.10),age (P = 0.77),proton-pump inhibitor use (P = 0.73),receipt of antibiotics (P = 0.66),and receipt of DNA hypomethylating agent-based chemotherapy (P = 0.92) were not significantly associated with CDI.CONCLUSION CDI is common in the MDS/AML population.Factors significantly associated with CDI in this population include low albumin,prior CDI,use of cytarabine-based chemotherapy,and prolonged neutropenia.In this study,we have identified a subset of patients in which prophylaxis studies could be targeted. | Kamini Shah Bryan F Curtin Christopher Chu Daniel Hwang Mark H Flasar Erik von Rosenvinge | 2017 | World Journal of Clinical Oncology2017，8，5： | 3 |
| 2 | Improving care for patients with dysphagia显示文摘 | Rosenvinge SK Starke ID | 2005 | Age Ageing2005，34，6： | 1 |
| 3 | A new rating scale for adult resilience:what are the central protective resources behindhealthy adjustment显示文摘 | Friborg O Hjemdal O Rosenvinge JH | 2003 | Int J Methods Psychiatr Res2003，12，2： | 1 |
| 4 | A new rating scale for adult resilience:What are the central protective resources be- hind healthy adjustment?显示文摘 | Friborg O Hjemdal O Rosenvinge J H | 2003 | Int J Methods Psychiatr Res2003，12，2： | 1 |
| 5 | A new rating scale for adult resilience: what are the central protective resources behind healthy adjustment? 显示文摘 | FRIBORG O HJEMDAL O ROSENVINGE J H | 2003 | International Journal of Methods in Psychiatric Research2003，12，： | 1 |
| 6 | Insulin resistance in patients with rheumatoid arthritis:effect of anti-TNFalpha therapy显示文摘 | Rosenvinge A Krogh-Madsen R Baslund B | 2007 | Scand J Rheumatol2007，36，2： | 1 |
| 7 | A new rating scale for adult resilience:What are the central protective resources behind healthy adjustment显示文摘 | Friborg O Hjemdal O Rosenvinge J H etal | 2003 | Int J Methods Psychiatric Res2003，12，： | 1 |
| 8 | A new rating scale foradult resilience : what are the central protective resources behindhealthy adjustment 显示文摘 | Friborg 0 Hjemdal 0 Rosenvinge JH | 2003 | Int J Methods Psychiatr Res2003，12，2： | 1 |
| 9 | A new rating scale for a- dult resilience: What are the central protective resources behind healthy adjustment显示文摘 | Friborg O Hjemdal O Rosenvinge J H | 2003 | International Journal of Methods in Psychiat- ric Research2003，12，2： | 1 |
| 10 | A new rating scale foradult resilience : what are the central protective resources behindhealthy adjustment? 显示文摘 | Friborg 0 Hjemdal 0 Rosenvinge JH | 2003 | International Journal of Methods inPsychiatric Research2003，12，2： | 1 |
| 11 | A new rating scale for adult resilience:what are the central pratective resources behind healthy adjustment? 显示文摘 | Friborg O Hjemdal O Rosenvinge JH | 2003 | INTERNATIONAL JOURNAL OF METHODS IN PSYCHIATRIC RESEARCH2003，12，2： | 1 |
| 12 | A New Rating Scale for Adult Resilience:What Are the Central Protective Resources behind Healthy Adjustment显示文摘 | Friborg O Hjemdal O Rosenvinge J H | | 0，，02： | 1 |
| 13 | Resilience in relation to personality and intelligence 显示文摘 | Friborg O Barlaug D Martinussen M Rosenvinge J H Hjem- dal O | 2005 | International Journal of Methods in Psychiatric Research2005，，： | 1 |
| 14 | A new rating scale for adult resilience: what are the central protective resources behind healthy adjust- ment显示文摘 | Friborg O Hjemdal O Rosenvinge J H | 2003 | International Journal of Methods in Psy- chiatric Research2003，12，2： | 1 |
| 15 | Gastrointestinal peptides and regulation of gastric acid secretion 显示文摘 | yon Rosenvinge EC Raufman JP | 2010 | Curr Opin Endocrinol Diabetes Obes2010，17，1： | 1 |
| 16 | A new rating scale for adult resilience: what are the central protective resources behind healthy adjustment 显示文摘 | Friborg O Hjemdal O Rosenvinge JH | 2003 | Int J Methods Psychiatr Res2003，12，2： | 1 |
| 17 | Clinical outcome and adverse effects of electroconvulsive therapy in elderly psychiatric patiems 显示文摘 | Kujala I Rosenvinge B Bekkelund SI | 2002 | J Geriatr Psychiatry Neurol2002，15，2： | 1 |
| 18 | A new rating scale for adult resilience--what are the central protective resources behind healthy adjustment? 显示文摘 | Friborg O Hjemdal O Rosenvinge J | 2003 | Int J Methods Psychiatr Res2003，12，2： | 1 |
| 19 | A New Rating Scale for Adult Resilience:What Are the Central Protective Resources behind Healthy Adjustment显示文摘 | Friborg O Hjemdal O Rosenvinge J H | 2003 | Int J Methods Psychiatr Res2003，12，2： | 1 |
| 20 | A new rat- ing scale for adult resilience:What are the central protec- tive resources behind healthy adjustment? 显示文摘 | Friborg O Hjemdal O Rosenvinge J H | 2003 | Int J Methods Psychiatr Res2003，12，2： | 1 |
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