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259篇 您的检索式:作者名="Rowlands H"
    题名 作者 年代 出处 被引量
1Transposon mouse models to elucidate the genetic mechanisms of hepatitis B viral induced hepatocellular carcinoma显示文摘The major type of human liver cancer is hepatocellular carcinoma(HCC), and there are currently many risk factors that contribute to this deadly disease. The majority of HCC occurrences are associated with chronic hepatitis viral infection, and hepatitis B viral(HBV) infection is currently a major health problem in Eastern Asia. Elucidating the genetic mechanisms associated with HBV-induced HCC has been difficult due to the heterogeneity and genetic complexity associated with this disease. A repertoire of animal models has been broadly used to study the pathophysiology and to develop potential treatment regimens for HBVassociated HCC. The use of these animal models has provided valuable genetic information and has been an important contributor to uncovering the factors involved in liver malignant transformation, invasion and metastasis. Recently, transposon-based mouse models are becoming more widely used in liver cancer research to interrogate the genome by forward genetics and also used to validate genes rapidly in a reverse genetic manner. Importantly, these transposon-based rapid reverse genetic mouse models could become crucial in testing potential therapeutic agents before proceeding to clinical trials in human. Therefore, this review will cover the use of transposon-based mouse models toaddress the problems of liver cancer, especially HBVassociated HCC occurrences in Asia.Amy P Chiu Barbara R Tschida Lilian H Lo Branden S Moriarity Dewi K Rowlands David A Largaespada Vincent W Keng 2015World Journal of Gastroenterology2015,21,42:2
2Impact of polymer films thickness and cavity size on polymer flow during embossing: Toward proces design rules for nanoimprint lithography显示文摘ROWLAND H D SUN A C SCHUNK P R 2005Journal of Micromechanics and Microengineering2005,15,:1
3Intestinal adenomatosis in the pig:Immunofluorescent and electron microscopic studies显示文摘Rowland A C Lawson G H K 1974Res Vet Sci1974,17,:1
4Researchers' e-journal use and information seeking behavior显示文摘Nicholas D Williams P Rowlands I Jamali H R 2010Journal of Information Science2010,,36:1
5Robotic cardiac surgery: advanced minimally invasive technology hindered by barriers to adoption 显示文摘Athanasiou T Ashrafian H Rowland SP 2011Future Cardiol2011,7,4:1
6Student digital information-seeking behavior in context显示文摘Nicholas D Huntington P Jamali H R Rowlands I Fieldhouse M 2009Journal of Documentation2009,65,1:1
7Heterogeneity of lobster agglutinins II,specificity of agglutininerythrocytes binding显示文摘James L H David T Rowland J 1974Biochemistry1974,13,4:1
8Polymer Deformation and Filling Modes during Microembossing显示文摘Rowland H D King W P 2004Journal of Micromechanics and Microengineering2004,14,:1
9Prebiotic effects: metabolic and health benefits显示文摘Roberfroid M Gibson G R Hoyles L McCartney A L Rastall R Rowland I Wolvers D Watztl B Szajewska H Stahl B Guarner F Respondek F Whelan K Coxam V Davieco M Laotoing L Wittrant Y Delzenne N Cani P Neyrinek A Meheust A 2010British Journal of Nutrition2010,104,2:1
10Explaining national climate change policies显示文摘IAN H ROWLANDS 1995Global Environmental Change1995,3,3:1
11Inhibitory effects of olive oil phenolics on invasion in human colon adenocarcinoma cells in vitro显示文摘Hashim Z H Rowland I R Mcglynn H 2008Int J Cancer2008,122,3:1
12Impact of Polymer Film Thickness and Cavity Size on Polymer Flow during Embossing:toward Process Design Rules for Nanoimprint Lithography显示文摘Rowland H D Sun A C Schunk P R 2005Journal of Micromechanics and Microengineering2005,15,:1
13Uptake of the pharmaceutical fluoxetine hydrochloride from growth medium by Brassicaceae显示文摘Redshawa C H Wootton V G Rowland S J 2008Phytochemistry2008,69,13:1
14Resonance-induced hydrogen bonding at sulfur acceptors in RtRzC = S and R~ CSE-systems 显示文摘ALLEN F H BIRD C M ROWLAND R S 1997Acta Cryst1997,53,4:1
15Methods and techniques to help quality function deployment(QFD)显示文摘Bouchereau V Rowlands H 2000The International Journal of Quality and Reliability Management2000,7,1:1
16Metabolism of isoflavones and lignans by the gut microflora:a study in germ-free and human flora associated rats显示文摘BOWEY E ADLERCREUTZ H ROWLAND I 2003Food Chem Toxicol2003,41,5:1
17Determinants of Energy Efficiency Behaviours in the Home: A Case Study of Waterloo Region显示文摘SCOTF D PARKER P ROWLANDS I H 2001Environments2001,28,3:1
18Growth of GaN,and AlGaN films and quantum well substrates by molecular beam epitaxy 显示文摘JOHNSON M A L HUGHES W C ROWLAND W H 1997J Cryst Growth1997,17,:1
19Metabolism of isoflavones and lignans by the gut microflora:a study in germ-free and human flora associated rats显示文摘BOWEY E ADLERCREUTZ H ROWLAND I 2003Food Chem Toxicol2003,41,5:1
20The effec-tiveness of Hawley and vacuum -formed retainers: A single-center randomized controlled trial显示文摘Rowland H Hichens L Williams A 2007Am J Orthod Dentofacial Orthop2007,132,6:1
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