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| 1 | Characterization of microbial communities in strong aromatic liquor fermentation pit muds of different ages assessed by combined DGGE and PLFA analyses显示文摘 | Jia Zheng Ru Liang Liqiang Zhang Chongde Wu Rongqing Zhou Xuepin Liao | 2013 | Food Research International2013，，1： | 1 |
| 2 | Neurochemical mechanism of the gastrointestinal interdigestive migrating motor complex in rats with acute inflammatory stomach ache显示文摘The normal gastrointestinal interdigestive migrating motor complex cycle was interrupted, and paroxysmal contraction appeared after formaldehyde-induced stomach ache. Activities of nitric oxide synthase, acetylcholinesterase and vasoactive intestinal peptide neurons were significantly reduced, whereas activities of calcitonin gene-related peptide neurons were significantly increased in the pyloric sphincter muscular layer, myenteric nerve plexus and submucous nerve plexus. Electroacupuncture at Zusanli (ST36) suppressed paroxysmal contraction in rats with formaldehyde-induced stomach ache, and neurons in the enteric nervous system were normal. These results indicated that nitrergic neurons, cholinergic neurons, vasoactive intestinal peptide neurons and calcitonin gene-related peptide neurons in the enteric nervous system may be involved in changes to the gastrointestinal interdigestive migrating motor complex following stomach ache, and that electroacupuncture can regulate this process. | Xiaoli Xu Qin Li Lv Zhou Liqiang Ru | 2012 | Neural Regeneration Research2012，7，27： | 1 |
| 3 | Deformation of cho- linergic (cholinesterase - positive) nerves of rectal mucous membrane in Hirschsprung's disease - a histochemical diagnosis using mucosal biopsies显示文摘 | Ai Minkang Guan Xinming Ru Liqiang el al | 1979 | Chin Med J(Engl)1979，92，2： | 1 |
| 4 | Lactoferrin improves hepatic pyroptosis in mice after irradiation显示文摘Objective:To investigate the effects of lactoferrin(Lf)on hepatic pyroptosis(an inflammatory form of programmed cell death)in mice exposed to radiation.Methods:A total of thirty-six BALB/c male mice were randomly divided into four groups,namely the control group,5 Gy group,5 Gyþ2 mg Lf group,and 5 Gyþ4 mg Lf group.The mice were administered whole-body ionizing radiation using a PRIMUS accelerator,with a single dose of 5 Gy and an absorbed dose rate of 2.0 Gy/min at a source-skin distance of 100 cm.Lf solution was intraperitoneally injected into the mice 2 h before and per day after radiation.The mice were sacrificed 1,3,and 9 d after radiation,and their livers were used for histopathologic examination,immunohistochemistry analysis,and Western blot analysis for absent in melanoma 2(AIM2)inflammasome pathway.Results:Histopathologic examination showed the disorder of the hepatocellular structure and the accumulation of inflammatory cells after radiation.Lf intervention inhibited hepatocellular proliferation and decreased the infiltration of inflammatory cells.Immunohistochemistry analysis indicated that AIM2 overexpression was significantly attenuated by 4 mg of Lf(t=3.065,P<0.05)3 d after radiation and by 2 mg and 4 mg of Lf(t=4.032,t=2.786,P<0.05)9 d after radiation.Western blot analysis showed that Lf downregulated the hepatic overexpression of AIM2,apoptosis-associated speck-like protein containing a caspase activation and recruitment domain(ASC),IL-1β,and IL-18.2 mg of Lf significantly downregulated the abovementioned protein expression 3 d(t=7.934,4.092,5.193,2.916,P<0.05)and 9 d after radiation(t=5.016,3.882,9.528,P<0.05 for AIM2,ASC,IL-1β).Conclusions:Lf intervention suppressed the hepatic pyroptosis in mice exposed to ionizing radiation by downregulating the protein expression of AIM2 inflammasome. | Ru Zhang Jia Gu Yulu Wei Yaxing Guo Liqiang Qin Jiaying Xu | 2022 | Radiation Medicine and Protection2022，3，1： | 0 |
| 5 | Preliminary research and scheme design of deep underground in situ geo-information detection experiment for Geology in Time显示文摘The deep earth,deep sea,and deep space are the main parts of the national“three deep”strategy,which is in the forefront of the strategic deployment clearly defined in China’s 14th Five-Year Plan(2021-2025)and the Long-Range Objectives Through the Year 2035.It is important to reveal the evolutionary process and mechanism of deep tectonics to understand the earth’s past,present and future.The academic con-notation of Geology in Time has been given for the first time,which refers to the multi-field evolution response process of geological bodies at different time and spatial scales caused by geological processes inside and outside the Earth.Based on the deep in situ detection space and the unique geological envi-ronment of China Jinping Underground Laboratory,the scientific issue of the correlation mechanism and law between deep internal time-varying and shallow geological response is given attention.Innovative research and frontier exploration on deep underground in situ geo-information detection experiments for Geology in Time are designed to be carried out,which will have the potential to explore the driving force of Geology in Time,reveal essential laws of deep earth science,and explore innovative technologies in deep underground engineering. | Heping Xie Ru Zhang Zetian Zhang Yinshuang Ai Jianhui Deng Yun Chen Yong Zhou Mingchuan Li Liqiang Liu Mingzhong Gao Zeqian Yang Weiqiang Ling Heng Gao Qijun Hao Kun Xiao Chendi Lou | 2024 | International Journal of Mining Science and Technology2024，34，1： | 0 |
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