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68篇 您的检索式:作者名="Ruehl"
    题名 作者 年代 出处 被引量
1ⅩⅧ型胶原mRNA在实验性肝纤维化大鼠肝脏中的表达显示文摘目的了解XⅧ型胶原(collagenXⅧ,CXⅧ)mRNA在实验性肝纤维化中的定量改变。方法以逆行胆管硬化注射加结扎的方法制备大鼠胆管堵塞性肝纤维化模型,以假手术组大鼠为对照组。提取肝脏总RNA,以核酸酶保护分析(RNA酶保护分析)定量测定前胶原α1(XⅧ)mRNA水平,并与α1(Ⅰ)和金属蛋白酶组织抑制因子1(TIMP-1)的mRNA变化相比较。结果与假手术组大鼠相比,胆管堵塞性肝纤维化大鼠肝脏前胶原α1(Ⅰ)及TIMP-1mRNA水平分别升高20倍及4倍;而肝纤维化大鼠肝脏前胶原α1(XⅧ)mRNA水平仅升高到1.8倍。结论肝纤维化时肝脏XⅧ胶原仅轻度升高.这种变化类型可能和XⅧ胶原主要由肝实质细胞表达有关。贾继东 Michael Bauer Garbriele Boigk Martin Ruehl Detlef Schuppan 王宝恩 2000中华肝脏病杂志2000,8,5:4
2Matrix as a modulator of hepatic fibrogenesis显示文摘SCHUPPAN D RUEHL M SOMASUNDARAM R 2001Semin Liver Dis2001,21,:1
3Extracts of Linderaobtusiloba induce antifibrotic effects in hepatic stellatecells via suppression of a TGF-beta-mediated profibroticgene expression pattern 显示文摘Ruehl M Erben U Kim K 2009J Nutr Biochem2009,20,8:1
4Matrix as a modulator of hepatic fibrogenesis显示文摘Schuppan D Ruehl M Somasundaram R 2001Semin Liver Dis2001,21,3:1
5Supercritical drying ofaerogel:insitu analysis of concentration profiles inside the gel and derivation of the effective binary diffusion coefficient using Raman spectroscopy显示文摘Qui(n)o J Ruehl M Klima T 2016The Journal of SupercriticalFluids2016,108,:1
6Antifibrotic effect of silymarin in rat secondary biliary fibrosis is mediated by downregulation of procollagen α 1(I) and TIMP-1显示文摘Ji-Dong Jia Michael Bauer Jae Jin Cho Martin Ruehl Stefano Milani Gabriele Boigk Ernst Otto Riecken Detlef Schuppan 2001Journal of Hepatology2001,,:1
7Matrix as a modulator of hepatic fibrogenesis显示文摘Schuppan D Ruehl M Somasundaram R 2001Semin Liver Dis2001,21,3:1
8An oral endothelin-A receptor antagonist blocks collagen synthesis and deposition in advanced rat liver fibrosis显示文摘Jae-Jin Cho Berthold Hocher Hermann Herbst Ji-Dong Jia Martin Ruehl Eckhart G. Hahn Ernst Otto Riecken Detlef Schuppan 2000Gastroenterology2000,,6:1
9Antifibrotic effect of silymarin in rat secondary biliary fibrosis is mediated by downregulation of procollagen alphal (Ⅰ) and TIMP-1显示文摘Jia JD Bauer M Cho JJ Ruehl M Milani S Boigk G 2001J Hepatol2001,35,:1
10Carbon dynamics of soil organic matter in bulk soil and aggregatefraction during secondary succession in a Mediterranean environment显示文摘Novara A Gristina L La Mantia T Ruehl J 2013Geoderma2013,193,:1
11Current Practices with Aluminum and hon Based Coagulants显示文摘KAREN E Ruehl 2001Public Works2001,,9:1
12Matrix as a modulator of hepatic fibrogenesis 显示文摘Schuppan D Ruehl M Somasundaram R 2001Semin Liver Dis2001,21,3:1
13Effect of intraocular lens optic edge design and anterior capsule polishing on posterior capsul fibrosis 显示文摘Sacu S Menapace R Ruehl W 2004J Cataract Refract Surg2004,30,3:1
14Extracts of Lindera obtusiloba induce antifibrotic effects in hepatic stellate cells via suppression of a TGF-beta-mediated profibrotic gene expression pattern显示文摘RUEHL M ERBEN U KIM K 2009J Nutr Biochem2009,20,8:1
15Matrix as a modulator of hepatic fibrogenesis显示文摘Schuppan D Ruehl M Somasundaram R 2001Semin Liver Dis2001,21,3:1
16A strain of Alternaria cirri Ellis and Pierce causing a leaf spot of rough lemon in Florida显示文摘Ruehle G 1937Phytopathology1937,27,:1
17Matrix as a modulator of heptic fibrogenesis显示文摘Schuppan D Ruehl M Somasundaram R 2001Semin Liver Dis2001,21,3:1
18Mycobacterium avium subspecies paratuberculosis infects and multiplies in enteric glial cells显示文摘AIM: To establish the role of enteric glial cells during infection with Mycobacterium avium subspecies paratuberculosis (MAP) in Crohn's disease. METHODS: In order to establish the role of enteric glial cells during infection with M. avium subspecies paratuberculosis (MAP) in Crohn's disease, Map adhesion experiments on enteric glial cells were performed as well as expression analysis of Map sigma factors during infection. RESULTS: In this study, for the first time, we found a high affinity of MAP to enteric glial cells and we analyzed the expression of MAP sigma factors under different conditions of growth. CONCLUSION: The fact that Map showed a high affinity to the glial cells raises concerns about the complicated etiology of the Crohn's disease. Elucidation of the mechanisms whereby inflammation alters enteric neural control of gut functions may lead to novel treatments for Crohn's disease.Leonardo A Sechi Anne Ruehl Niyaz Ahmed Donatella Usai Daniela Paccagnini Giovanna E Felis Stefania Zanetti 2007World Journal of Gastroenterology2007,13,43:1
19Localization of brain stem motoneurons innervating the laryngeal muscles in the rufous horseshoe bat,Rhinolophus rouxi显示文摘 Ruebsamen R Ruehle C 1981Brain Res1981,230,12:1
20A strain of Alternaria citri Ellis and Pierce caus?ing a leaf spot of rough lemon in Florida显示文摘RUEHLE G D 1937Phytopathology1937,27,:1
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