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| 1 | Helicobacter pylori Induces Increased Expression of Toll‐Like Receptors and Decreased Toll‐Interacting Protein in Gastric Mucosa that Persists Throughout Gastric Carcinogenesis显示文摘 | Pedro Pimentel‐Nunes Nádia Gon?alves Inês Boal‐Carvalho Luís Afonso Paula Lopes Roberto Roncon‐Albuquerque Rui Henrique Luís Moreira‐Dias Adelino F. Leite‐Moreira Mário Dinis‐Ribeiro | 2012 | Helicobacter2012，，1： | 2 |
| 2 | Modification of wheat straw lignin by solid state fermentation with white-rot fungi显示文摘 | Maria J. Dinis Rui M.F. Bezerra Fernando Nunes Albino A. Dias Cristina V. Guedes Luís M.M. Ferreira John W. Cone Guilhermina S.M. Marques Ana R.N. Barros Miguel A.M. Rodrigues | 2009 | Bioresource Technology2009，，20： | 1 |
| 3 | Single Carrier Modu- lation With Nonlinear Frequency Domain Equaliza- tion:An Idea Whose Time Has Come Again 显示文摘 | Nevio Benvenuto Rui Dinis | 2010 | IEEE Proceedings2010，98，1： | 1 |
| 4 | Single Carrier Modu- lation With Nonlinear Frequency Domain Equaliza- tion:An Idea Whose Time Has Come Again显示文摘 | Nevio Benvenuto Rui Dinis | | 0，，01： | 1 |
| 5 | A reduced-CP approach to SC/FDE block transmission for broadband wireless communications显示文摘 | Antonio Gusmao Paulo Tortes Rui Dinis | 2007 | IEEE Trans Comm2007，55，4： | 1 |
| 6 | BLEED-Myocardial Infarction Score:Predicting mid-term post-discharge bleeding events显示文摘AIM:To derive and validate a score for the prediction of mid-term bleeding events following discharge for myocardial infarction(MI).METHODS:One thousand and fifty patients admitted for MI and followed for 19.9 ± 6.7 mo were assigned to a derivation cohort.A new risk model,called BLEEDMI,was developed for predicting clinically significant bleeding events during follow-up(primary endpoint) and a composite endpoint of significant hemorrhage plus all-cause mortality(secondary endpoint),incorporating the following variables:age,diabetes mellitus,arterial hypertension,smoking habits,blood urea nitrogen,glomerular filtration rate and hemoglobin at admission,history of stroke,bleeding during hospitalization or previous major bleeding,heart failure during hospitalization and anti-thrombotic therapies prescribedat discharge.The BLEED-MI model was tested for calibration,accuracy and discrimination in the derivation sample and in a new,independent,validation cohort comprising 852 patients admitted at a later date.RESULTS:The BLEED-MI score showed good calibration in both derivation and validation samples(HosmerLemeshow test P value 0.371 and 0.444,respectively) and high accuracy within each individual patient(Brier score 0.061 and 0.067,respectively).Its discriminative performance in predicting the primary outcome was relatively high(c-statistic of 0.753 ± 0.032 in the derivation cohort and 0.718 ± 0.033 in the validation sample).Incidence of primary/secondary endpoints increased progressively with increasing BLEED-MI scores.In the validation sample,a BLEED-MI score below 2 had a negative predictive value of 98.7%(152/154) for the occurrence of a clinically significant hemorrhagic episode during follow-up and for the composite endpoint of post-discharge hemorrhage plus all-cause mortality.An accurate prediction of bleeding events was shown independently of mortality,as BLEED-MI predicted bleeding with similar efficacy in patients who did not die during follow-up:Area Under the Curve 0.703,Hosmer-Lemeshow test P value 0.547,Brier score 0.060;low-risk(BLEED-MI score 0-3) event rate:1.2%;intermediate risk(score 4-6) event rate:5.6%;high risk(score ≥ 7) event rate:12.5%.CONCLUSION:A new bedside prediction-scoring model for post-discharge mid-term bleeding has been derived and preliminarily validated.This is the first score designed to predict mid-term hemorrhagic risk in patients discharged following admission for acute MI.This model should be externally validated in larger cohorts of patients before its potential implementation. | Sérgio Barra Rui Providência Francisca Caetano Inês Almeida Luís Paiva Paulo Dinis António Leito Marques | 2013 | World Journal of Cardiology2013，5，6： | 0 |
| 7 | Overview of resistant hypertension:A glimpse of the cardiologist's current standpoint显示文摘Hypertension is a major risk factor for cardiovascular disease,resulting in increased incidence of cerebrovascular events,ischaemic heart disease,heart failure,and renal impairment.Thus,it is one of the most important preventable causes of premature morbidity and mortality.Despite current knowledge on the management of hypertension and the availability of several effective antihypertensive medications,uncontrolled hypertension remains a common and challenging clinical problem.Resistant hypertension is a complex condition with multiple contributing factors and overlapping comorbidities.Although there is limited hard evidence regarding resistant hypertension,our understanding of this condition has improved recently.This article will present an overview of resistant hypertension and highlight recent publications about this topic. | Luis Paiva Maria Carmo Cachulo Rui Providencia Sergio Barra Paulo Dinis Antonio Leitao-Marques | 2012 | World Journal of Cardiology2012，4，9： | 0 |
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