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| 1 | Effect of loading rates on the characteristics of thermal damage for mudstone under different temperatures显示文摘The uniaxial compression tests for mudstone specimens are carried out with four different loading rates from room temperature to 400℃ by using the Rock Mechanics Servo-controlled Testing System MTS810 and high temperature furnace MTS652.02.The mechanical properties of mudstone with various loading rates are studied under different temperature conditions.The results show that when temperature increases from room temperature to 400℃ and loading rate is less than 0.03 mm/s,the peak strength of mudstone specimen decreases as loading rate increases,while the various peak strengths show significant differences when loading rate exceeds 0.03 mm/s.At room temperature,the elastic modulus decreases at the first time and then increases with loading rate rising.When the temperature is between200 and 400℃,the elastic modulus presents a decreasing trend with increasing loading rate.With increasing the loading rate,the number of fragments in mudstone becomes larger and even the powder is observed in mudstone with higher loading rate.Under high loading rate,the failure mode of mudstone specimens under different temperatures is mainly conical damage. | Mao Rongrong Mao Xianbiao Zhang Lianying Liu Ruixue | 2015 | International Journal of Mining Science and Technology2015，25，5： | 7 |
| 2 | Distinct immune signatures discriminate between asymptomatic and presymptomatic SARS-CoV-2^(pos)subjects显示文摘Increasing numbers of SARS-CoV-2-positive(SARS-CoV-2^(pos))subjects are detected at silent SARS-CoV-2 infection stage(SSIS).Yet,SSIS represents a poorly examined time-window wherein unknown immunity patterns may contribute to the fate determination towards persistently asymptomatic or overt disease.Here,we retrieved blood samples from 19 asymptomatic and 12 presymptomatic SARS-COV-2^(pos)subjects,47 age/gender-matched patients with mild or moderate COVID-19 and 27 normal subjects,and interrogated them with combined assays of 44-plex CyTOF,RNA-seq and Olink.Notably,both asymptomatic and presymptomatic subjects exhibited numerous readily detectable immunological alterations,while certain parameters including more severely decreased frequencies of CD107a^(low)classical monocytes,intermediate monocytes,non-classical monocytes and CD62L^(hi)CD8^(+)Tnaive cells,reduced plasma STC1 level but an increased frequency of CD4^(+)NKT cells combined to distinguish the latter.Intercorrelation analyses revealed a particular presymptomatic immunotype mainly manifesting as monocytic overactivation and differentiation blockage,a likely lymphocyte exhaustion and immunosuppression,yielding mechanistic insights into SSIS fate determination,which could potentially improve 5ARS-CoV-2 management. | Shanhe Yu Caixia Di Shijun Chen Mingquan Guo Jiayang Yan Zhaoqin Zhu Li Liu Ruixue Feng Yinyin Xie Ruihong Zhang Juan Chen Mengxi Wang Dong Wei Hai Fang Tong Yin Jinyan Huang Saijuan Chen Hongzhou Lu Jiang Zhu Jieming Qu | 2021 | Cell Research2021，31，11： | 4 |
| 3 | Macroscopic and microscopic fracture features of concrete used in coal mine under chlorine salt erosion显示文摘The microscopic morphology and pore structure characteristics of concrete with composite admixtures(fly ash and mineral powder) after chlorine salt erosion were analyzed via scanning electron microscopy(SEM) and mercury injection porosimetry(MIP), providing the basis for the design and maintenance of concrete shafts in coal mines. The above-mentioned characteristics were compared with the macroscopic characteristic of concrete fractures under uniaxial compression. The results show that the macroscopic fracture characteristics of concrete under uniaxial compression change from longitudinal split fracture and oblique section shear fracture to conjugate cant fracture, and the degree of breakage increases.Interface cracks, cement paste cracks, spherical surface cracks, and aggregate cracks appear in concrete under uniaxial compression. In the early stages of corrosion, the original cracks which are obvious are repaired. When the corrosion becomes more serious, cement paste cracks appear, and the number of harmful holes increases while the number of harmless holes decreases. This study also reveals the relationship between the macroscopic properties and microscopic structure of concrete under chloride salt erosion. Finally, the paper preliminarily discussed the relationship between the macroscopic properties and mesoscopic characteristics of concrete under chlorine salt erosion. | Li Bing Yin Huiguang Mao Xianbiao Li Yan Zhang Lianying Liu Ruixue Qiu Peitao | 2016 | International Journal of Mining Science and Technology2016，26，3： | 4 |
| 4 | Flood-illuminated adaptive optics ophthalmoscope with a single curved relay mirror显示文摘For decreasing light loss and diminishing the aberrations of the optical system,an open-loop adaptive optics(AO)system for retinal imaging in vivo is introduced.Taking advantage of the ability of young human eyes to accommodate,there was only one single curved mirror to make the pupil of the eye conjugate with the wavefront corrector and the wavefront sensor.A liquid crystal spatial light modulator(LC-SLM)was adopted as the wavefront corrector because the LC-SLM can be made in a small size to match the sensor.To reduce a pair of lenses or focusing mirrors,the wavefront corrector and sensor are positioned in the noncommon path.The system adopts open-loop control and the high-precision LC-SLM guarantees the effectiveness of the AO system.The designed field of view is 1°on the retina(about 300μm).The image quality was simulated with different mirror surface types,including circular,parabolic,and hyperbolic.A hyperbolic mirror with conic constant−1.07,which is close to−1,could best eliminate the aberrations.Theoretical analysis showed that the optical throughput of this system was at least 22.4%higher than that of a standard transmission AO system.In a practical experiment,a parabolic mirror was positioned in the optical path.Images of the cone photoreceptors and the capillary vessels were obtained successfully.This system simplifies the optical setup in comparison to the commonly used 4F systems while still guaranteeing the effectiveness of AO to correct the ocular aberrations. | Ruixue Liu Yue Qi Xianliang Zheng Mingliang Xia Li Xuan | 2013 | Photonics Research2013，1，3： | 3 |
| 5 | Sustainable H2 production from ethanol steam reforming over a macro-mesoporous Ni/Mg-Al-O catalytic monolith显示文摘macro-meso-porous 整体的基于 Ni 的催化剂作为模板用聚苯乙烯泡沫经由一条受精线路被准备然后在乙醇改过生产 H2 富有的气体的蒸气使用了。Ni/Mg-Al 催化剂有一层次地由相片和扫描电子显微镜学(SEM ) 显示了的 macro-meso-porous 结构。催化剂的表面区域是 230 | Ruixue GU Guangming ZENG Jingjing SHAO Yuan LIU Johannes W. Schwank Yongdan LI | 2013 | Frontiers of Chemical Science and Engineering2013，7，3： | 2 |
| 6 | Inactivation of Staphylococcus aureus and Enterococcus faecalis by a direct-current,cold atmospheric-pressure air plasma microjet显示文摘Objective:A direct-current,cold atmospheric-pressure air plasma microjet(PMJ)was performed to inactivate Staphylococcus aureus(S.aureus)and Enterococcus faecalis(E.faecalis)in air.The process of sterilization and morphology of bacteria was observed.We wish to know the possible inactivation mechanisms of PMJ and explore a potential application in dental and other temperature sensitive treatment.Methods:In this study,we employed a direct current,atmospheric pressure,cold air PMJ to inactivate bacterias.Scanning electron microscopy was employed to evaluate the morphology of S.aureus and showed rupture of cell walls after the plasma treatment and Optical emission spectrum(OES)were used to understand the possible inactivation mechanisms of PMJ.Results:The inactivation rates could reach 100%in 5 min.When the distance between the exit nozzle of the PMJ device and Petri dish was extended from 1 cm to 3 cm,effective inactivation was also observed with a similar inactivation curve.Conclusion:The inactivation of bacteria is attributed to the abundant reactive oxygen and nitrogen species,as well as ultroviolet radiation in the plasma.Different life spans and defensibilities of these killing agents may hold the key to understanding the different inactivation curves at different treatment distances. | Ye Tian Peng Sun Haiyan Wu Na Bai Ruixue Wang Weidong Zhu Jue Lnang Fuxiang Liu | 2010 | The Journal of Biomedical Research2010，24，4： | 2 |
| 7 | SARS-CoV-2 crosses the blood-brain barrier accompanied with basement membrane disruption without tight junctions alteration显示文摘SARS-CoV-2 has been reported to show a capacity for invading the brains of humans and model animals.However,it remains undear whether and how SARS-CoV-2 crosses the blood-brain barrier(BBB).Herein,SARS-CoV-2 RNA was occasionally detected in the vascular wall and perivascular space,as well as in brain microvascular endothelial cells(BMECs)in the infected K18-hACE2 transgenic mice.Moreover,the permeability of the infected vessel was in creased.Furthermore,disin tegrity of BBB was discovered in the infected hamsters by administration of Evans blue.Interestingly,the expression of claudin5,ZO-1,occludin and the ultrastructure of tight junctions(TJs)showed unchanged,whereas,the basement membrane was disrupted in the infected animals.Using an in vitro BBB model that comprises primary BMECs with astrocytes,SARS-CoV-2 was found to infect and cross through the BMECs.Consistent with in vivo experiments,the expression of MMP9 was increased and collagen IV was decreased while the markers for TJs were not altered in the SARS-CoV-2-infected BMECs.Besides,inflammatory responses including vasculitis,glial activation,and upregulated inflammatory factors occurred after SARS-CoV-2 infection.Overall,our results provide evidence supporting that SARS-CoV-2 can cross the BBB in a transcellular pathway accompanied with basement membrane disrupted without obvious alteration of TJs. | Ling Zhang Li Zhou Linlin Bao Jiangning Liu Hua Zhu Qi Lv Ruixue Liu Wei Chen Wei Tong Qiang Wei Yanfeng Xu Wei Deng-Hong Gao Jing Xue Zhiqi Song Pin Yu Yunlin Han Yu Zhang Xiuping Sun Xuan Yu Chuan Qin | 2021 | Signal Transduction and Targeted Therapy2021，6，10： | 2 |
| 8 | Polarization-sensitive and wide-spectrum photovoltaic detector based on quasi-1D ZrGeTe_(4)nanoribbon显示文摘Low-dimensional semiconductors with in-plane anisotropy and narrow bandgap have been extensively applied to polarized detection in the near-infrared(NIR)region.However,the narrow bandgap can cause noise owing to the high dark current in photodetectors.This article reports quasi-1D ZrGeTe_(4)nanoribbonbased photodetectors with low dark current and broadband polarization detection.The photodetector was fabricated by evaporating 50-nm-thick Au electrodes on a ZrGeTe_(4)nanoribbon.Benefiting from the photovoltaic characteristics in the ZrGeTe_(4)nanoribbon and Au electrodes,these photodetectors can operate without bias voltage,with decreased dark current,and improved device performance.Furthermore,the quasi-1D ZrGeTe_(4)nanoribbon-based photodetectors demonstrate a polarization sensitivity in a broadband from visible(VIS)to the NIR region,such as a high photoresponsivity of 625.65 mA W1,large external quantum efficiency of 145.9%at 532 nm,and photocurrent anisotropy ratio of 2.04 at 1064 nm.They exhibit a novel perpendicular optical reversal of 90in polarization-sensitive photodetection,angle-resolved absorption spectra,and azimuth-dependent reflectance difference microscopy(ADRDM)from VIS to the NIR region,as opposed to other nanoribbon-based polarization-sensitive photodetectors.This work paves the way for utilizing photovoltaic photodetectors based on low-dimensional materials for broad-spectrum polarized photodetection. | Ruixue Bai Tao Xiong Jinshu Zhou Yue-Yang Liu Wanfu Shen Chunguang Hu Faguang Yan Kaiyou Wang Dahai Wei Jingbo Li Juehan Yang Zhongming Wei | 2022 | InfoMat2022，4，3： | 2 |
| 9 | The effects of repeated propofol anesthesia on spatial memory and long-term potentiation in infant rats under hypoxic conditions显示文摘Propofol is widely used as an intravenous drug for induction and maintenance in general anesthesia.Hypoxemia is a common complication during perianesthesia.We want to know the effect of propofol on spatial memory and LTP(Long-term potentiation)under hypoxic conditions.In this study,84 seven-day-old SpragueeDawley rats were randomly assigned into six groups(n Z 14)-four control groups:lipid emulsion solvent t 50%oxygen(CO),lipid emulsion solvent t room air(CA),lipid emulsion solvent t 18%oxygen(CH),and propofol t 50%oxygen(propofoleoxygen,PO);and two experiment groups:propofol t room air(propofol eair,PA),and propofol t 18%oxygen(propofolehypoxia,PH).After receiving propofol(50 mg/kg)or the same volume of intralipid intraperitoneal(5.0 ml/kg),injected once per day for seven consecutive days,the rats were exposed to 18%oxygen,50%oxygen and air,until recovery of the righting reflex.We found that the apoptotic index and activated caspase-3 increased in the PH group(P<0.05)compared with the PA group,fEPSP(field excitatory postsynaptic)potential and success induction rate of LTP reduced in all propofol groups(P<0.05).Compared with the PO group,the fEPSP and success induction rate of LTP reduced significantly in the PA and PH groups(P<0.05).Moreover,compared with CH group,the average time of escape latency was longer,and the number of platform location crossings was significantly reduced in the PH group(P<0.05).Thus,we believe that adequate oxygen is very important during propofol anesthesia. | Mang Sun Ruixue Yuan Hui Liu Jing Zhang Shengfen Tu | 2020 | Genes & Diseases2020，7，2： | 2 |
| 10 | Thermoresponsive copolymers: from fundamental studies to applications显示文摘 | Ruixue Liu Michael Fraylich Brian R. Saunders | 2009 | Colloid and Polymer Science2009，，6： | 1 |
| 11 | A four-miRNA signature identified from genome-wide serum miRNA profiling predicts survival in patients with nasopharyngeal carcinoma显示文摘 | LIU Na CUI Ruixue SUN Ying | 2014 | Ant J Cancer2014，134，6： | 1 |
| 12 | Prognostic value of a microRNA signature in nasophatyngeal carcinoma: a microRNA expression analysis显示文摘 | LIU Na CHEN Nianyong CUI Ruixue | 2012 | Lancet Oncol2012，13，6： | 1 |
| 13 | Performance simulation and optimization of new radiant floor heating based on micro heat pipe array显示文摘This paper proposes two new radiant floor heating structures based on micro heat pipe array(MHPA),namely cement-tile floor and keel-wood floor.The numerical models for these different floor structures are established and verified by experiments.The temperature distribution and heat transfer process of each part are comprehensively obtained,and the structure is optimized.The results show that the cement-tile floor has the better heat transfer performance of the two.When under the same inlet water temperature and flow rate,the keel-wood floor's surface temperature distribution is about 2℃ lower than that of the cement-tile floor.The inlet water temperature of cement-tile floor is about 10℃ lower than that of keel-wood structure when the floor surface temperature is the same.During a longitudinal heat transfer above MHPA,the floor surface temperature decreases by 0.5℃ for every 10 mm filling layer increase.In order to reduce the non-uniformity of the floor's surface temperature and improve the thermal comfort of the heated room,the optimal structure for a floor is given,with the maximum surface temperature difference reduced by 3.35℃.We used research focusing on new radiant floor heating,with advantages including high efficiency heat transfer,low water supply temperature,simple waterway structure,low resistance and leakage risk,to provide theory and data to support the application of an effective radiant floor heating based on MHPA. | Heran Jing Zhenhua Quan Ruixue Dong Limin Hao Yunhan Liu Yaohua Zhao | 2022 | Building Simulation2022，15，7： | 1 |
| 14 | A Fault Current Limiting Hybrid DC Circuit Breaker显示文摘Due to the low impedance characteristic of the high voltage direct current(HVDC)grid,the fault current rises extremely fast after a DC-side fault occurs,and this phenomenon seriously endangers the safety of the HVDC grid.In order to suppress the rising speed of the fault current and reduce the current interruption requirements of the main breaker(MB),a fault current limiting hybrid DC circuit breaker(FCL-HCB)has been proposed in this paper,and it has the capability of bidirectional fault current limiting and fault current interruption.After the occurrence of the overcurrent in the HVDC grid,the current limiting circuit(CLC)of FCL-HCB is put into operation immediately,and whether the protected line is cut off or resumed to normal operation is decided according to the fault detection result.Compared with the traditional hybrid DC circuit breaker(HCB),the required number of semiconductor switches and the peak value of fault current after fault occurs are greatly reduced by adopting the proposed device.Extensive simulations also verify the effectiveness of the proposed FCL-HCB. | Lei Huang Qian Zhang Wenlei Liu Ruixue Liu | 2022 | Energy Engineering2022，119，2： | 1 |
| 15 | Prediction of adolescent subjective well being: A machine learning approach显示文摘Background Subjective well-being(SWB),also known as happiness,plays an important role in evaluating both mental and physical health.Adolescents deserve specific attention because they are under a great variety of stresses and are at risk for mental disorders during adulthood.Aim The present paper aims to predict undergraduate students1 SWB by machine learning method.Methods Gradient Boosting Classifier which was an innovative yet validated machine learning approach was used to analyse data from 10518 Chinese adolescents.The online survey included 298 factors such as depression and personality.Quality control procedure was used to minimise biases due to online survey reports.We applied feature selection to achieve the balance between optimal prediction and result interpretation.Results The top 20 happiness risks and protective factors were finally brought into the predicting model.Approximately 90%individuals'SWB can be predicted correctly,and the sensitivity and specificity were about 92%and 90%,respectively.Conclusions This result identifies at-risk individuals according to new characteristics and established the foundation for adolescent prevention strategies. | Naixin Zhang Chuanxin Liu Zhixuan Chen Lin An Decheng Ren Fan Yuan Ruixue Yuan Lei Ji Yan Bi Zhenming Guo Gaini Ma Fei Xu Fengping Yang Liping Zhu Gabirel Robert Yifeng Xu Lin He Bo Bai Tao Yu Guang He | 2019 | General Psychiatry2019，32，5： | 1 |
| 16 | Theoretical study of reduction mechanism of Fe_(2)O_(3) by H_(2) during chemical looping combustion显示文摘An atomic-level insight into the H_(2)adsorption and oxidation on the Fe_(2)O_(3)surface during chemicallooping combustion was provided on the basis of density functional theory calculations in this study.The results indicated that H_(2)molecule most likely chemisorbs on the Fe_(2)O_(3)surface in a dissociative mode.The decomposed H atoms then could adsorb on the Fe and O atoms or on the two neighboring O atoms of the surface.In particular,the H_(2)molecule adsorbed on an O top site could directly form H_(2)O precursor on the O_(3)-terminated surface.Further,the newly formed H-O bond was activated,and the H atom could migrate from one O site to another,consequently forming the H_(2)O precursor.In the H_(2)oxidation process,the decomposition of H_(2)molecule was the rate-determining step for the O_(3)-terminated surface with an activation energy of 1.53 eV.However,the formation of H_(2)O was the ratedetermining step for the Fe-terminated surface with an activation energy of 1.64 eV.The Feterminated surface is less energetically favorable for H_(2)oxidation than that the O_(3)-terminated surface owing to the steric hindrance of Fe atom.These results provide a fundamental understanding about the reaction mechanism of Fe_(2)O_(3)with H_(2),which is helpful for the rational design of Fe-based oxygen carrier and the usage of green energy resource such as H_(2). | Feng Liu Jing Liu Yu Li Ruixue Fang | 2021 | Chinese Journal of Chemical Engineering2021，34，9： | 1 |
| 17 | Microstructures, mechanical properties and in vitro corrosion behavior of biodegradable Zn alloys microalloyed with Al, Mn, Cu, Ag and Li elements显示文摘In this work,Zn microalloyed with Al,Mn,Cu,Ag and Li was cast,annealed and extruded.The results showed that addition of multiple trace elements causes significant change in the microstructures,mechanical properties and corrosion behavior of Zn-0.1Al-0.1Mn-0.1Cu-0.1Ag(^(1)ZM),Zn-0.1Al-0.1Mn-0.1Cu0.1Ag-0.1Li(^(2)ZM-0.1Li)and Zn-0.1Al-0.1Mn-0.1Cu-0.1Ag-0.35Li(^(3)ZM-0.35Li)alloys.Two ternary phases with the approximate compositions of Al_(13)Mn_(3)Zn_(34) and Al_(10)MnZn_(89) phases are formed in the casting and annealing processes of these alloys,respectively.Wavyβ-LiZn_(4) lamellae that have not been extensively reported are precipitated from the primary Zn dendrites in the casting process of ZM-0.35Li alloy.Also,Zn laths are precipitated from the eutecticβ-LiZn_(4) phase in the annealing process of ZM-0.35Li alloy.The above-mentioned phases are crushed or elongated in the as-extruded alloys,which play an important role in improving the strength of the alloys.All the as-extruded alloys have typical(0001)basal texture,accompanied with relatively low{0001}<1120>slip and high{1012}<1011>twinning Schmid factors,which are advantageous and disadvantageous to the strength enhancement of the alloys,respectively.All the as-cast alloys exhibit poor mechanical properties,especially low ductility.The as-extruded ZM alloy exhibits ultrahigh ductility,with an elongation of up to 82.2%±2.94%.The as-extruded ZM0.35Li alloy shows the best comprehensive mechanical properties,with yield strength,ultimate tensile strength,elongation and hardness of 380±1.6 MPa,449±7.4 MPa,62.3%±4.63%and 98±1.4 HV,respectively.Electrochemical corrosion rates of the ZM,ZM-0.1Li and ZM-0.35Li alloys are 0.241±0.004,0.206±0.006 and 0.189±0.008 mm/year,respectively.In vitro immersion corrosion rates(after 26 d in SBF solution)of them are 0.134±0.005,0.125±0.004 and 0.121±0.003 mm/year,respectively.The as-extruded ZM-0.35Li alloy exhibits the best corrosion resistance. | Lei Li Huanzheng Jiao Congfu Liu Lin Yang Yusong Suo Ruixue Zhang Tie Liu Jianzhong Cui | 2022 | Journal of Materials Science & Technology2022，，8： | 1 |
| 18 | Recent advances in engineering iron oxide nanoparticles for effective magnetic resonance imaging显示文摘Iron oxide nanoparticle(IONP)with unique magnetic property and high biocompatibility have been widely used as magnetic resonance imaging(MRI)contrast agent(CA)for long time.However,a review which comprehensively summarizes the recent development of IONP as traditional T_(2) CA and its new application for different modality of MRI,such as T_(1) imaging,simultaneous T_(2)/T_(1) or MRI/other imaging modality,and as environment responsive CA is rare.This review starts with an investigation of direction on the development of high-performance MRI CA in both T_(2) and T_(1) modal based on quantum mechanical outer sphere and Solomon-Bloembergen-Morgan(SBM)theory.Recent rational attempts to increase the MRI contrast of IONP by adjusting the key parameters,including magnetization,size,effective radius,inhomogeneity of surrounding generated magnetic field,crystal phase,coordination number of water,electronic relaxation time,and surface modification are summarized.Besides the strategies to improve r2 or r1 values,strategies to increase the in vivo contrast efficiency of IONP have been reviewed from three different aspects,those are introducing second imaging modality to increase the imaging accuracy,endowing IONP with environment response capacity to elevate the signal difference between lesion and normal tissue,and optimizing the interface structure to improve the accumulation amount of IONP in lesion.This detailed review provides a deep understanding of recent researches on the development of high-performance IONP based MRI CAs.It is hoped to trigger deep thinking for design of next generation MRI CAs for early and accurate diagnosis. | Zhenghuan Zhao Muyao Li Jie Zeng Linlin Huo Kun Liu Ruixue Wei Kaiyuan Ni Jinhao Gao | 2022 | Bioactive Materials2022，7，6： | 1 |
| 19 | Ho 3+ doped fluorophosphate glasses sensitized by Yb 3+ for efficient 2μm laser applications显示文摘 | Hongfei Chen Fangze Chen Tao Wei Qunhuo Liu Ruixu Shen Ying Tian | 2014 | Optics Communications2014，，： | 1 |
| 20 | Microsecond pulse driven Ar/CF4 plasma jet forpolymethylmethacrylate surface modification at atmosphericpressure 显示文摘 | Wang Ruixue Zhang Cheng Liu Xiong | 2015 | Applied Surface Science2015，328，： | 1 |
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