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| 1 | Clinical features,histology,and histogenesis of combined hepatocellular-cholangiocarcinoma显示文摘Combined hepatocellular-cholangiocarcinoma(CHC) is a rare tumor with poor prognosis,with incidence ranging from 1.0%-4.7% of all primary hepatic tumors.This entity will be soon renamed as hepato-cholangiocarcinoma.The known risk factors for hepatocellular carcinoma(HCC) have been implicated for CHC including viral hepatitis and cirrhosis.It is difficult to diagnose this tumor pre-operatively.The predominant histologic component within the tumor largely determines the predominant radiographic features making it a difficult distinction.Heterogeneous and overlapping imaging features of HCC and cholangiocarcinoma should raise the suspicion for CHC and multiple core biopsies(from different areas of tumor) are recommended before administering treatment.Serum tumor markers CA19-9 and alpha-fetoprotein can aid in the diagnosis,but it remains a challenging diagnosis prior to resection.There is sufficient data to support bipotent hepatic progenitor cells as the cell of origin for CHC.The current World Health Organization classification categorizes two main types of CHC based on histo-morphological features:Classical type and CHC with stem cell features.Liver transplant is one of the available treatment modalities with other management options including transarterial chemoembolization,radiofrequency ablation,and percutaneous ethanol injection.We present a review paper on CHC highlighting the risk factors,origin,histological classification and therapeutic modalities. | Shweta Gera Mark Ettel Gabriel Acosta-Gonzalez Ruliang Xu | 2017 | World Journal of Hepatology2017，9，6： | 13 |
| 2 | Clinical and biological significance of precursor lesions of intrahepatic cholangiocarcinoma显示文摘Cholangiocarcinoma(CC) is primarily a malignant tumor of older adults most prevalent in Southeast Asia,where liver fluke infestation is high.However the etiology in western countries is unknown.Although the incidence of extrahepatic cholangiocarcinoma has remained constant,incidence of intrahepatic CC(ICC) which differs inmorphology,pathogenesis,risk factors,treatment and prognosis is increasing.While this increase is associated with hepatitis C virus infection,chronic nonalcoholic liver disease,obesity,and smoking,the pathogenesis of ICC and molecular alterations underlying the carcinogenesis are not completely elucidated.Benign biliary lesions such as biliary intraepithelial neoplasia,intraductal papillary neoplasm of the bile duct,von Meyenburg complex or bile duct hamartoma,and bile duct adenoma have been associated with ICC.For each of these entities,evidence suggests or supports a role as premalignant lesions.This article summarized the important biological significance of the precursor lesions of ICC and the molecular mechanisms that may be involved in intrahepatic cholangiocarcinogenesis. | Mark Ettel Ogechukwu Eze Ruliang Xu | 2015 | World Journal of Hepatology2015，7，25： | 3 |
| 3 | Amorphous TiO_2-supported Keggin-type ionic liquid catalyst catalytic oxidation of dibenzothiophene in diesel显示文摘Supported ionic liquid(IL) catalysts [C_nmim]_3PMo_(12)O_(40)/Am TiO_2(amorphous TiO_2) were synthesized through a one-step method for extraction coupled catalytic oxidative desulfurization(ECODS) system. Characterizations such as FTIR, DRS,wide-angle XRD, N_2 adsorption–desorption and XPS were applied to analyze the morphology and Keggin structure of the catalysts. In ECODS with hydrogen peroxide as the oxidant, it was found that ILs with longer alkyl chains in the cationic moiety had a better effect on the removal of dibenzothiophene. The desulfurization could reach 100% under optimal conditions, and GC–MS analysis was employed to detect the oxidized product after the reaction. Factors affecting the desulfurization efficiencies were discussed, and a possible mechanism was proposed. In addition, cyclic experiments were also conducted to investigate the recyclability of the supported catalyst. The catalytic activity of [C_(16)mim]_3 PMo_(12)O_(40)/Am TiO_2 only dropped from 100% to 92.9% after ten cycles, demonstrating the good recycling performance of the catalyst and its potential industrial application. | Zhendong Yu Donghui Wang Suhang Xun Minqiang He Ruliang Ma Wei Jiang Hongping Li Wenshuai Zhu Huaming Li | 2018 | Petroleum Science2018，15，4： | 3 |
| 4 | Human activities and elevational constraints restrict ranging patterns of snub-nosed monkeys in a mountainous refuge显示文摘Both natural conditions and anthropogenic factors affect the survivability,distribution,and population density of wildlife.To understand the extent and how these factors drive species distributions,a detailed description of animal movement patterns in natural habitats is needed.In this study,we used satellite telemetry to monitor elevational ranges favored by endangered golden snub-nosed monkeys(Rhinopithecus roxellana),in the Qinling Mountains,central China.We investigated the abundance and distribution of food resources through sampling vegetation quadrats at different elevations and sampled anthropogenic activities using field surveys.Our results indicated that although there was no significant variation in food resources between low-(<1500 m)and middle-elevations(1500–2200 m),monkeys were found most often in areas above 1500 m,where there was less anthropogenic development(e.g.houses and roads);however,monkeys rarely ranged above 2200 m and had limited food availability at this altitude.There was limited human disturbance at this elevation.We suggest that both human activity and ecological constraints(i.e.food resources)have considerable effects on elevational use of R.roxellana in the Qinling Mountains.This study highlights the critical roles these factors can play in shaping the vertical distribution of high-altitude primates.This research provides useful insights for habitat-based conservation plans in which human disturbance management and habitat restoration should be prioritized. | Pengzhen HUANG Kun BIAN Zhipang HUANG Qi Li Derek WDUNN Gu FANG Jiahui LIU Mengyao WANG Xianfeng YANG Ruliang PAN Cunlao GAO Kaichuang SI Baoguo LI Xiaoguang QI | 2021 | Integrative Zoology2021，16，2： | 3 |
| 5 | Using unmanned aerial vehicles with thermal-image acquisition cameras for animal surveys:a case study on the Sichuan snub-nosed monkey in the Qinling Mountains显示文摘Following significant developments in technology,alternative devices have been applied in fieldwork for animal and plant surveys.Thermal-image acquisition cameras installed on unmanned aerial vehicles(UAVs)have been used in animal surveys in the wilderness.This article demonstrates an example of how UAVs can be used in high mountainous regions,presenting a case study on the Sichuan snub-nosed monkey with a detection rate of 65.19%for positive individual identification.It also presents a model that can prospectively predict population size for a given animal species,which is based on combined initial work using UAVs and traditional surveys on the ground.A great potential advantage of UAVs is significantly shortening survey procedures,particularly for areas with high mountains and plateaus,such as the Himalayas,the Qinghai-Tibet Plateau,Hengduan Mountains,the Yunnan-Gui Plateau and Qinling Mountains in China,where carrying out a traditional survey is extremely difficult,so that species and population surveys,particularly for critically endangered animals,are largely absent.This lack of data has impacted the management of endangered animals as well as the formulation and amendment of conservation strategies. | Gang HE Haitao YANG Ruliang PAN Yewen SUN Pengbin ZHENG Jinghua WANG Xuelin JIN Jingjie ZHANG Baoguo LI Songtao GUO | 2020 | Integrative Zoology2020，15，1： | 2 |
| 6 | Co-Expression of XIAP and Cyclin D1 Complex Correlates with a Poor Prognosis in Patients with Hepatocellular Carcinoma显示文摘 | Yufang Che Fei Ye Ruliang Xu Haitao Qing Xinying Wang Fei Yin Miao Cui David Burstein Bo Jiang David Y. Zhang | 2012 | The American Journal of Pathology2012，，5： | 1 |
| 7 | Zonula occludens toxin structure-function analysis:identification of the fragment biologically active on tight junctions and of the zonulin receptor binding domain显示文摘 | MARINAROSARIA T DI PIERRO Y RULIANG H | 2001 | Biol Chem2001，276，19： | 1 |
| 8 | Optimal dietary protein and lipid levels f or juvenile cobia (Rachycentron canadum) 显示文摘 | CHOU Ruliang SU Maosen CHE Houngyung | 2001 | Aquaculture2001，193，： | 1 |
| 9 | Toll-Like Receptor-4 Promotes the Development of Colitis-Associated Colorectal Tumors显示文摘 | Masayuki Fukata Anli Chen Arunan S. Vamadevan Jason Cohen Keith Breglio Suneeta Krishnareddy David Hsu Ruliang Xu Noam Harpaz Andrew J. Dannenberg Kotha Subbaramaiah Harry S. Cooper Steven H. Itzkowitz Maria T. Abreu | 2007 | Gastroenterology2007，，6： | 1 |
| 10 | Gliadin Induces an Increase in Intestinal Permeability and Zonulin Release by Binding to the Chemokine Receptor CXCR3显示文摘 | Karen M. Lammers Ruliang Lu Julie Brownley Bao Lu Craig Gerard Karen Thomas Prasad Rallabhandi Terez Shea-Donohue Amir Tamiz Sefik Alkan Sarah Netzel–Arnett Toni Antalis Stefanie N. Vogel Alessio Fasano | 2008 | Gastroenterology2008，，1： | 1 |
| 11 | Metrical Dental Analysis on Golden Monkey (Rhinopithecus Roxellana) 显示文摘 | RULIANG P CHARLESOXNAR D | 2001 | PRIMATES2001，42，1： | 1 |
| 12 | Mandibular Variation Among Chinese Macaques显示文摘 | RULIANG P CHARLESOXNAR D NICK M | 2002 | American Journal of Primatology2002，56，： | 1 |
| 13 | Facial expression recognition in golden snub-nosed monkeys显示文摘For socialized animals,such as prinlates,emotions arc the expression of internal states,which may be recognized by others to adjust an in dividual's potential actions(Girard and Bellone 2020).Facial expressions are therefore important signals in communication(e.g.,happy or in pain)and can help individuals understand potential meanings between each other(Dolensek et al.2020).Facial expressions can be expressed and processed freely and are useful in social interactions and bonding(Waller et al.2016). | Haitao Zhao Jiaxuan Li Xiaowei Wang Ruliang PAN Chengliang Wang Yi Ren Yan Wang Baoguo Li | 2020 | Current Zoology2020，66，6： | 1 |
| 14 | Constructing a novel QoS aggregated model based on KBPP 显示文摘 | Xiao Ruliang | 2010 | Communications in Computer and Information Science2010，107，3： | 1 |
| 15 | Extinction of Snub-Nosed Monkeys in China During the Past 400 Years显示文摘 | Baoguo Li Ruliang Pan Charles E. Oxnard | 2002 | International Journal of Primatology2002，，6： | 1 |
| 16 | 基于红外相机技术监测秦岭山地引水工程对大中型兽类种群影响的初报显示文摘2015年1月—2016年12月,采用红外相机技术在陕西省引汉济渭工程作业区设置4个监测点,对保护兽类种群变化进行了监测研究。监测共发现大中型陆栖兽类3目9科9种,其中,川金丝猴Rhinopithecus roxellana、秦岭羚牛Budorcas bedfordi和林麝Moschus berezovskii为国家Ⅰ级重点保护野生动物,野猪Sus scrofa和黄鼬Mustela sibirica在监测中的遇见频次最多。随着工程的推进,与2015年相比,2016年监测发现的物种数量和遇见频次均呈减少的趋势。这说明该工程带来的人为干扰、噪音、景观的改变对区内栖息的野生动物具有不利的影响,已经出现动物活动减少、发生迁移的现象,这有可能会进一步影响秦岭动物群落结构和种群空间分布。建议加强动物种群变化监测,减少人为干扰,严格控制动物栖息地破坏程度,做好景观和植被恢复工程。 | 何刚 郭松涛 金学林 张河 石智慧 刘弈辰 李东群 贾康胜 郑鹏斌 PAN Ruliang 李保国 | 2018 | 四川动物2018，37，4： | 1 |
| 17 | Adaptive neural control for MIMO nonlinear systems with state time-varying delay显示文摘在这份报纸,适应神经控制为在块三角形的控制的非线性的未知州的变化时间的延期系统组织的多输入多产量(MIMO ) 的一个类被建议。光线的基础功能(RBF ) 神经网络(NN ) 被利用估计未知连续功能。未知变化时间的延期被补偿在设计使用不可分类型的 Lyapunov-Krasovskii functionals。我们的结果的主要优点高效地不仅避免控制器奇特,而且在未知虚拟控制系数上放松限制。所有信号在的固定 MIMO 非线性的系统靠近环被完成,当系统的产量被证明收敛到需要的轨道的一位小邻居时。可行性被二个模拟例子调查。 | Ruliang WANG Kunbo MEI Chaoyang CHEN Yanbo LI Hebo MEI Zhifang YU | 2012 | 控制理论与应用(英文版)2012，10，3： | 1 |
| 18 | 佛坪自然保护区川金丝猴种群动态(英文)显示文摘陕西佛坪国家级保护区是我国重要的自然保护区之一,包括大熊猫、金丝猴在内的很多珍稀濒危物种分布其中。20世纪90年代后期,全国林业开始实施'天然林保护工程',这对佛坪保护区当地的农业、工业、经济发展和生活质量产生了很大的影响。为了探究'天然林保护工程'对野生川金丝猴的保护产生何种影响,我们于2015年至2016年采用访问调查和实地踏查方法对佛坪保护区20世纪90年代至今的川金丝猴种群动态变化进行研究,结果发现不论是种群数量(从少于500只增至671只左右)还是栖息地面积(从147.8 km^2增至236.5 km^2)都明显增长;家域范围随着年代的推移向低海拔位置扩大(秋季平均海拔为1 680 m±304 m),越来越靠近人类;川金丝猴在家域范围内,对常绿阔叶林和落叶阔叶林有明显的选择偏好,活动比例分别达到了40.11%和38.41%。实施'天然林保护工程'后,当地农业开发和经济活动在逐渐转型,减少了人类活动对野生动物栖息地的干扰,提升了栖息地保护的质量和生态环境。因此,此项工程的实施在该地区川金丝猴保护方面表现出积极的效果,促进了当地金丝猴栖息地的改善,种群数量得以增加扩大,是一个野生动物保护的成功案例。 | 何刚 郭松涛 金学林 贺树军 李芳芳 李财 吴帆 侯荣 黄康 何祥博 刘新玉 Ruliang Pan 李保国 | 2018 | 兽类学报2018，38，3： | 1 |
| 19 | Synthesis andinsecticidal activity of novel carbamate derivatives as potentialdual-binding site acetylcholinesterase inhibitors显示文摘 | Ma Hongju Xie Ruliang Zhao Qianfei | 2010 | J Agric Food Chem2010，58，12： | 1 |
| 20 | A new three-dimen- sional imaging algorithm for airborne forward-looking SAR 显示文摘 | Ren Xiaozhen Sun Jiantao Yang Ruliang | 2011 | IEEE Geoscience and Remote Sensing Letters2011，8，1： | 1 |
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