|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Involvement of serum retinoids and Leiden mutation in patients with esophageal, gastric, liver, pancreatic, and colorectal cancers in Hungary显示文摘AIM: To analyze the serum levels of retinoids and Leiden mutation in patients with esophageal, gastric, liver,pancreatic, and colorectal cancers.METHODS: The changes in serum levels of retinoids (vitamin A, α- and β-carotene, α- and β-cryptoxanthin,zeaxanthin, lutein) and Leiden mutation were measured by high liquid performance chromatography (HPLC)and polymerase chain reaction (PCR) in 107 patients (70 males/37 females) with esophageal (0/8), gastric (16/5), liver (8/7), pancreatic (6/4), and colorectal (30/21including 9 patients suffering from in situ colon cancer)cancer. Fifty-seven healthy subjects (in matched groups)for controls of serum retinoids and 600 healthy blood donors for Leiden mutation were used.RESULTS: The serum levels of vitamin A and zeaxanthin were decreased significantly in all groups of patients with gastrointestinal (GI) tumors except for vitamin A in patients with pancreatic cancer. No changes were obtained in the serum levels of α- and β-carotene,α- and β-cryptoxanthin, zeaxanthin, lutein in patients with GI cancer. The prevalence of Leiden mutation significantly increased in all groups of patients with GI cancer.CONCLUSION: Retinoids (as environmental factors)are decreased significantly with increased prevalence of Leiden mutation (as a genetic factor) in patients before the clinical manifestation of histologically different (planocellular and hepatocellular carcinoma, and adenocarcinoma) GI cancer. | Gyula Mózsik Gy(o|¨)rgy Rumi András D(o|¨)m(o|¨)t(o|¨)r Mária Figler Beáta Gasztonyi El(?)d Papp Alajos Pár Gabriella Pár József Belágyi Zoltán Matus Béla Melegh | 2005 | World Journal of Gastroenterology2005，11，48： | 2 |
| 2 | Clinical effect of driver mutations of JAK2, CALR, or MPL in primary myelofibrosis 显示文摘 | Rumi E Pietra D Pascutto C | 2014 | Blood2014，124，7： | 1 |
| 3 | JAK2 or CALR mutation status defines subtypes of essentialthrombocythemia with substantially different clinical course and outcomes显示文摘 | Rumi E Pietra D Ferretti V | 2014 | Blood2014，123，10： | 1 |
| 4 | Deep sequencing reveals double mutations in cis of MPL exon 10 in myeloproliferative neoplasms显示文摘 | Pietra D Brisci A Rumi E | | 0，，04： | 1 |
| 5 | Relation between JAK2 (V617F) mutation status, granulocytic activation, and constitutive mobilization of CD34 cells into peripheral blood nmyeloproliferative disorders 显示文摘 | PASSAMONTI F RUMI E PIETRA D | 2006 | Blood2006，107，9： | 1 |
| 6 | JAK2 orCALR mutation status defines of essential thromboeythemia with substantially Different clinical course and outcomes显示文摘 | Rumi E Pietra D ferretti V | 2014 | Blood2014，123，10： | 1 |
| 7 | CALR exon 9 mutations are somatically acquired events in familial cases of essential thrombocythemia or primary myelofibrosis显示文摘 | Rumi E Harutyunyan AS Pietra D | 2014 | Blood2014，123，15： | 1 |
| 8 | Relation between J AK2 (V617F) mutation status,granulocyte activation, and constitutive mobilization of CD34+ cells into peripheral blood in myeloproliferative disorders显示文摘 | PASSAMONTI F RUMI E PIETRA D | 2006 | Blood2006，107，： | 1 |
| 9 | Relation between JAK2 (V617F)mutation status,granulocyte activation,and constitutive mobilization of CD34 + cells into peripheral blood in myeloprollferative disorders显示文摘 | Passamonti F Rumi D Pietra D | 2006 | Blood2006，107，： | 1 |
| 10 | JAK2 or CALR mutation sta- tus defines subtypes of essential thrombocythemia with substantially different clinical course and outcomes 显示文摘 | Rumi E Pietra D Ferretti V | 2014 | Blood2014，123，10： | 1 |
| 11 | Inference in hybrid Bayesian networks显示文摘 | Langseth H Nielsen T D Rumi R | 2009 | Reliability Engineering&System Safety2009，94，10： | 1 |
| 12 | Clinical effect of driver mutations of JAK2, CALR, or MPL in primary myelofibrosis 显示文摘 | Rumi E Pietra D Pascutto C | 2014 | Blood2014，124，7： | 1 |
| 13 | Relation between JAK2 (V617F) mutation status,granulocyte activation,and constitutive mobilization of CD34+ cells into peripheral blood in myeloproliferative disorders显示文摘 | PASSAMONTI F RUMI E PIETRA D | 2006 | Blood2006，107，： | 1 |
| 14 | Design of organic molecules with large two- photon absorption cross sections 显示文摘 | Albota M Beljonne D Br6das J L Ehrlich J E Fu J Y Heikal A A Hess S E Kogej T Leving M D Marder S R McCord-Maughon D Perry J W Roeckel H Rumi M Subramaniam G Webb W W Wu X L Xu C | 1998 | Science1998，281，： | 1 |
| 15 | 浓缩血小板保存期间的磷脂酰丝氨酸暴露不同的细胞分离机采集的血小板之间的差异显示文摘在真核细胞中磷脂酰丝氨酸(PS)在质膜的内外分布不对称.在血小板中也有这种PS在双分子层中的选择定位通过ATP依赖性氨基磷脂移位酶来产生和维持这种选择性定位.一些机制与血小板膜外部PS暴露增加有关:公认的机制是ATP水平降低的代谢损伤,以及血小板激活.而且一些作者提出与年龄有关的氧化还原状态改变对膜的脂质转运蛋白产生氧化损伤的可能性. | Lai M Rumi C D'onofrio G 洪缨 | 2004 | 国外医学(输血及血液学分册)2004，27，4： | 1 |
| 16 | Relation between JAK2(V617F) mutation status,granulocytic activation,and constitutive mobilization of CD34+ cells into peripheral blood in myeloproliferative disorders显示文摘 | Passamonti F Rumi E Pietra D | 2006 | Blood2006，107，9： | 1 |
| 17 | Dep sequencing reveals double mulalions in cis d' MPL exon 10 in myelnproliferalive neoplasms 显示文摘 | Pielra D Brisci A Rumi E el al | 2011 | Haematologica2011，96，4： | 1 |
| 18 | Clinical effect of driver nmtalions of JAK2,CAI,R,or MPI, in prima myelofibrnsis 显示文摘 | Rumi E Pielra D Pascutto C | 2014 | Blood2014，124，7： | 1 |
| 19 | Mutation type as a major determinant of clinical phenotype in myeloprolfferative neoplasms associated with mutant calreticulin 显示文摘 | Pietra D Rumi E Milanesi C | 2014 | Blood ( ASH annual meeting Abstracts )2014，124，21： | 1 |
| 20 | Improvement of quality of life in allergic rhinoconjunctivitis patients using nasal filters, a pre- liminary study显示文摘 | D'Amato G D'Amato M Rumi G | 2013 | Eur Ann Allergy Clin Immunol2013，45，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员