维普期刊资源整合服务平台（V6.5）

29篇 您的检索式：作者名="Ryan LJ"

选中清除导出查看参考文献查看引证文献引用追踪共2页首页上一页第1页下一页末页 /2 跳转

	题名	作者	年代	出处	被引量
1	In vivo radiometric analysis of glucose uptake and distribution in mouse bone显示文摘Bone formation and remodeling occurs throughout life and requires the sustained activity of osteoblasts and osteoclasts,particularly during periods of rapid bone growth.Despite increasing evidence linking bone cell activity to global energy homeostasis,little is known about the relative energy requirements or substrate utilization of bone cells.In these studies,we measured the uptake and distribution of glucose in the skeleton in vivo using positron-emitting^(18)F-fluorodeoxyglucose([^(18)F]-FDG) and non-invasive,high-resolution positron emission tomography/computed tomography(PET/CT) imaging and ex vivo autoradiography.Assessment of [^(18)F]-FDG uptake demonstrated that relative to other tissues bone accumulated a significant fraction of the total dose of the glucose analog.Skeletal accumulation was greatest in young mice undergoing the rapid bone formation that characterizes early development.PET/CT imaging revealed that [^(18)F]-FDG uptake was greatest in the epiphyseal and metaphyseal regions of long bones,which accords with the increased osteoblast numbers and activity at this skeletal site.Insulin administration significantly increased skeletal accumulation of [^(18)F]-FDG,while uptake was reduced in mice lacking the insulin receptor specifically in osteoblasts or fed a high-fat diet.Our results indicated that the skeleton is a site of significant glucose uptake and that its consumption by bone cells is subject to regulation by insulin and disturbances in whole-body metabolism.	Meredith L Zoch Diane S Abou Thomas L Clemens Daniel LJ Thorek Ryan C Riddle	2016	Bone Research2016，4，1：	9
2	Cognition and diabetes:a lifespan perspective显示文摘	Biessels GJ Deary LJ Ryan CM	2008	Lancet Neurol2008，7，2：	1
3	Growth and gene expression are predominantly controlled by distinct regions of the human IL - 4 receptor 显示文摘	Ryan J J McReynolds LJ Keegan A	2006	Immunity2006，4，2：	1
4	Growth and gene expression are predominantly cont rolled by distinct regions of the human IL-4 receptor显示文摘	Ryan JJ McReynolds LJ Keegan A	1996	Immunity1996，4，2：	1
5	Long-term survival after surgery versus percutaneous intervention in octogenarians with multivessel coronary disease显示文摘	Dacey LJ Likosky DS Ryan TJ	2007	Ann Thorac Surg2007，84，6：	1
6	Epstein-Barr virus(EBV)DNA in plasma is not encapsidated in patients with EBV-related malignancies显示文摘	Ryan JL Fan H Swinnen LJ	2004	Diagn Mol Pthol2004，13，2：	1
7	Crowt h and gene expression are predominantly cont rolled by distinct regions of the human IL-4 receptor显示文摘	Ryan JJ McReynolds LJ Keegan A	1996	Immunity1996，4，2：	1
8	Paradoxical use of a demand pacemaker in the treatment of supraventricular tachycardia due to the WPW syndrome: observations on termination of reciprocal rhythm 显示文摘	Ryan GF Easly R Zanoff LJ	1968	Circulation1968，38，：	1
9	Pramlintide in the treatment of type 1 and type 2 diabetes mellitus显示文摘	Ryan GJ Jobe LJ Martin R	2005	Clin Ther2005，27，10：	1
10	Differential expression of a cysteine rich domain in the amino - terminal propeptide of type Ⅱ (cartilage) procollagen by alternative splicing of mRNA 显示文摘	Ryan MC Sandell LJ	1990	Biolchem1990，，10：	1
11	Growth and gene expression are predominantly controlled by distinct regions of the human IL-4 receptor显示文摘	Ryan JJ McReynolds LJ Keegan A	1996	Immunity1996，4，2：	1
12	Episodic neurological channelopathies 显示文摘	Ryan DP Ptacek LJ	2010	Neu- ron2010，68，2：	1
13	Use of therapeutic plasma exchange in the management of acute hemorrhagic leukoencephalitis: a case report and review of the literature 显示文摘	Ryan LJ Bowman R Zantek ND	2007	Transfusion2007，47，6：	1
14	Opioid analgesics and rates of fatal drug poisoning in the United States显示文摘	Paulozzi LJ Ryan GW		0，，06：	1
15	Pramlintide in the treatment of type 1 and type 2 diabetes mellitus显示文摘	RYAN GJ JOBE LJ MARTIN R	2005	Clin Ther2005，27，10：	1
16	Growth and gene expression are predominantly controlled by distinct regions of the human IL-4 receptor显示文摘	Ryan JJ McReynolds LJ Keegan A Wang LH Garfein E Rothman P		0，，02：	1
17	Use of therapeutic plasma exchange in the management of acute hemorrhagic leukoencephalitis: A case report and review of the literature 显示文摘	Ryan LJ Bowman R Zantek ND	2007	Transfusion2007，47，6：	1
18	Blockade of PD1 and TIM3 restores innate and adaptive immunity in patients with acute alcoholic hepatitis 显示文摘	Markwiek LJ Riva A Ryan JM	2015	Gastroenterology2015，148，3：	1
19	Long-term survival after surgery versus percutaneous intervention in octogenarians with multivessel coronary disease 显示文摘	Dacey LJ Likosky DS Ryan TJ Jr	2007	Ann Thorac Surg2007，84，6：	1
20	Episodic neurological channelopathies显示文摘	Ryan DP Ptácek LJ		0，，02：	1

返回顶部每页显示：

共2页首页上一页第1页下一页末页 /2 跳转

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

用户提示