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16篇 您的检索式:作者名="Ryukichi"
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1Usefulness of urinary trypsinogen-2 and trypsinogen activation peptide in acute pancreatitis:A multicenter study in Japan显示文摘BACKGROUND Rapid urinary trypsinogen-2 dipstick test and levels of urinary trypsinogen-2 and trypsinogen activation peptide(TAP) concentration have been reported as prognostic markers for the diagnosis of acute pancreatitis.AIM To reconfirm the validity of all these markers in the diagnosis of acute pancreatitis by undertaking a multi-center study in Japan.METHODS Patients with acute abdominal pain were recruited from 17 medical institutions in Japan from April 2009 to December 2012. Urinary and serum samples were collected twice, at enrollment and on the following day for measuring target markers. The diagnosis and severity assessment of acute pancreatitis were assessed based on prognostic factors and computed tomography(CT) Grade of the Japanese Ministry of Health, Labour, and Welfare criteria.RESULTS A total of 94 patients were enrolled during the study period. The trypsinogen-2 dipstick test was positive in 57 of 78 patients with acute pancreatitis(sensitivity,73.1%) and in 6 of 16 patients with abdominal pain but without any evidence of acute pancreatitis(specificity, 62.5%). The area under the curve(AUC) score of urinary trypsinogen-2 according to prognostic factors was 0.704, which was highest in all parameter. The AUC scores of urinary trypsinogen-2 and TAP according to CT Grade were 0.701 and 0.692, respectively, which shows higher than other pancreatic enzymes. The levels of urinary trypsinogen-2 and TAP were significantly higher in patients with extended extra-pancreatic inflammation as evaluated by CT Grade.CONCLUSION We reconfirmed urinary trypsinogen-2 dipstick test is useful as a marker for the diagnosis of acute pancreatitis. Urinary trypsinogen-2 and TAP may be considered as useful markers to determine extra-pancreatic inflammation in acute pancreatitis.Hiroaki Yasuda Keisho Kataoka Yoshifumi Takeyama Kazunori Takeda Tetsuhide Ito Toshihiko Mayumi Shuji Isaji Tetsuya Mine Motoji Kitagawa Seiki Kiriyama Junichi Sakagami Atsushi Masamune Kazuo Inui Kenji Hirano Ryukichi Akashi Masamichi Yokoe Yoshio Sogame Kazuichi Okazaki Chie Morioka Yasuyuki Kihara Shigeyuki Kawa Masao Tanaka Akira Andoh Wataru Kimura Isao Nishimori Junji Furuse Isao Yokota Tooru Shimosegawa 2019World Journal of Gastroenterology2019,25,1:7
2Hepatitis C Virus Down-Regulates Insulin Receptor Substrates 1 and 2 through Up-Regulation of Suppressor of Cytokine Signaling 3显示文摘Takumi Kawaguchi Takafumi Yoshida Masaru Harada Takao Hisamoto Yumiko Nagao Tatsuya Ide Eitaro Taniguchi Hiroto Kumemura Shinichiro Hanada Michiko Maeyama Shinji Baba Hironori Koga Ryukichi Kumashiro Takato Ueno Hisanobu Ogata Akihiko Yoshimura Michio Sat 2004The American Journal of Pathology2004,,5:5
3Hepatitis C Virus Down-Regulates Insulin Receptor Substrates 1 and 2 through Up-Regulation of Suppressor of Cytokine Signaling 3显示文摘Takumi Kawaguchi Takafumi Yoshida Masaru Harada Takao Hisamoto Yumiko Nagao Tatsuya Ide Eitaro Taniguchi Hiroto Kumemura Shinichiro Hanada Michiko Maeyama Shinji Baba Hironori Koga Ryukichi Kumashiro Takato Ueno Hisanobu Ogata Akihiko Yoshimura Michio Sat 2004The American Journal of Pathology2004,,5:4
4Mechanism of pancreatitis caused by ERCP显示文摘Ryukichi akashi Takeaki kiyozumi Tomofum tanaka 2002Gastrointest Endosc2002,55,:1
5The effect of grain size on the tensile properties of magnox ALSO显示文摘RYUKICHI NAGASAKI KENSUKE SHIRAISI-IP 1965Journal of Nuclear Science & Technology1965,2,9:1
6Hepatitis C Virus Down-Regulates Insulin Receptor Substrates 1 and 2 through Up-Regulation of Suppressor of Cytokine Signaling 3显示文摘Takumi Kawaguchi Takafumi Yoshida Masaru Harada Takao Hisamoto Yumiko Nagao Tatsuya Ide Eitaro Taniguchi Hiroto Kumemura Shinichiro Hanada Michiko Maeyama Shinji Baba Hironori Koga Ryukichi Kumashiro Takato Ueno Hisanobu Ogata Akihiko Yoshimura Michio Sat 2004The American Journal of Pathology2004,,5:1
7Sonographic demonstration of wall thickness of the gallbladder in pediatric patients with pancreatico-biliary maljunction显示文摘Michihiro Sugai Keinosuke Ishido Masaaki Endoh Ryukichi Hada Hirohumi Munakata 2010Journal of Hepato - Biliary - Pancreatic Sciences2010,,3:1
8Brightening of roselle and kenaf chemi-thermomechanical pulps by conventional and refiner blcaching显示文摘Masashi Nishiyama Ryukichi Matsuo Yoshinari Kobayashi 1984Holzforschung1984,38,2:1
9Autocrine motility factor enhances hepatoma cell invasion across the basement membrane through activation of β1 integrins显示文摘Takuji Torimura Takato Ueno Motoaki Kin Riko Harada Toru Nakamura Takumi Kawaguchi Masaru Harada Ryukichi Kumashiro Hideomi Watanabe Raz Avraham Michio Sata 2001Hepatology2001,,1:1
10Energy problems and energy control system in the Japanese steel industry 显示文摘Ryukichi Ohkuma Katsuhide Ikegami Shunichi Yasunaga 1981IIE Transactions1981,13,2:1
11Erythropoietic protoporphyria with fatal liver failure显示文摘Akiko Ishibashi Riko Ogata Shotaro Sakisaka Ryukichi Kumashiro Yuriko Koga Keiichi Mitsuyama Ryoko Kuromatsu Yasuyo Uchimura Hiroyasu Ijyuin Kumi Tanaka Tadashi Iwao Kunihide Ishii Michio Sata Yoshiko Inoue Yasuko Kin Kotaro Oizumi Hidemi Nishida Tsutomu 1999Journal of Gastroenterology1999,,3:1
12Assessment of 287 Japanese cases of drug induced liver injury by the diagnostic scale of the International Consensus Meeting显示文摘Hajime Takikawa Yoriyuki Takamori Teru Kumagi Morikazu Onji Masaaki Watanabe Akitaka Shibuya Akiko Hisamochi Ryukichi Kumashiro Tadashi Ito Yasuhide Mitsumoto Atsushi Nakamura Takashi Sakaguchi 2003Hepatology Research2003,,3:1
13Mechanism of pancreatitis caused by ERCP显示文摘Ryukichi Akashi Takeaki Kiyozumi Tomofumi Tanaka Kouichi Sakurai Yasushi Oda Katsuro Sagara 2002Gastrointestinal Endoscopy2002,,1:1
14Brightening of roselle and kenaf chemi- thermomechanical pulps by conventional and refiner bleaching 显示文摘Masashi Nishiyama Ryukichi Matsuo and Yoshinari Kobayashi 1984Holzforschung1984,38,2:1
15Hepatitis C Virus Down-Regulates Insulin Receptor Substrates 1 and 2 through Up-Regulation of Suppressor of Cytokine Signaling 3显示文摘Takumi Kawaguchi Takafumi Yoshida Masaru Harada Takao Hisamoto Yumiko Nagao Tatsuya Ide Eitaro Taniguchi Hiroto Kumemura Shinichiro Hanada Michiko Maeyama Shinji Baba Hironori Koga Ryukichi Kumashiro Takato Ueno Hisanobu Ogata Akihiko Yoshimura Michio Sat 2004The American Journal of Pathology2004,,5:1
16Mechanism of pancreatitis caused by ERCP显示文摘RYUKICHI AKASHI TAKEAKI KIYOZUMI TOMOFUMI TANAKA 2002Gastrontest Endosc2002,55,1:1
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