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1822篇 您的检索式:作者名="S Walsh"
    题名 作者 年代 出处 被引量
1利用常间回文重复序列丛集介导的基因编辑评估Tet2和甲基转移酶3a在克隆性造血和心血管病中的作用显示文摘克隆性血细胞生成与死亡率、心血管病发生率增加有关。这种情况可能是由于造血干/祖细胞(hematopoietic stem/progenitor cells,HSPC)内的前白血病驱动基因的体细胞突变引起的。大约有40个候选驱动基因已被确定出来,但有研究证明在这些基因中,仅一个基因[10-11易位-2(TET2)]的突变在大鼠模型中可导致心血管病。Sano S Ohshima K Wang Y Katanasaka Y Sano M Walsh K 刘青 叶鹏 2018中华高血压杂志2018,26,7:11
2澳大利亚临床共识指南:儿童卒中的诊断和急性期处理显示文摘卒中是导致儿童死亡的十大原因之一,幸存的致残患儿将面临几十年的残疾生活,给患儿及其家庭带来了巨大负担。由于安全性和有效性的证据有限,以及诊断的延误,目前卒中患儿无法接受再灌注治疗。儿童卒中诊断和急性期处理的澳大利亚临床共识指南,旨在最大限度地减少临床诊疗中的不确定性,并记录与成人卒中不同的危险因素、病因和假性卒中情况的最佳证据。临床问题的阐述来自于对2007年至2017年数据库的系统检索,但仅限于英语和儿科研究。该指南应用SIGN方法和国家健康与医学研究委员会系统对证据进行筛选和分类,通过推荐、评估、发展和评价系统(GRADE系统)对推荐进行强弱分级。该指南提供了60多项基于证据的推荐,以帮助参与院前和急症处理的临床医师快速识别儿童卒中,选择最合适的初步检查方案来确定诊断、明确病因,并选择最恰当的干预措施以挽救脑组织、预防复发。同时,指南也提供了颅内压和先天性心脏病管理方面的推荐。该指南的实施需要将院前和急诊系统重组,包括建立区域性卒中网络,建立儿科卒中疾病编码,快速MRI,以及对能够提供再灌注治疗的初级儿科卒中中心进行认证。该指南能够审核治疗的基准时间线,获得急性期的干预措施及预后判断。它还将促进澳大利亚儿童卒中登记的发展,并与国际登记处建立数据联系,以便准确收集卒中发病率、治疗和结果相关的数据。Medley TL Miteff C Andrews I Ware T Cheung M Monagle P Mandelstam S Wray A Pridmore C Troedson C Dale RC Fahey M Sinclair A Walsh P Stojanovski S Macka MT 徐佳丽(译) 吴川杰(译) 肖潇(译) 吕俊萱(译) 张博维(译) 吉训明(译) 2019中国脑血管病杂志2019,16,4:9
3Causes of encephalitis and differences in their clinical presentations in England: a multicentre, population-based prospective study显示文摘Julia Granerod Helen E Ambrose Nicholas WS Davies Jonathan P Clewley Amanda L Walsh Dilys Morgan Richard Cunningham Mark Zuckerman Ken J Mutton Tom Solomon Katherine N Ward Michael PT Lunn Sarosh R Irani Angela Vincent David WG Brown Natasha S Crowcroft 2010The Lancet Infectious Diseases2010,,12:2
4Chelex 100 as a medium for simple extraction of DNA for PCR-based typing from forensic material 显示文摘Walsh P S Metzger D A Higuchi R 1991Bio Techniques1991,10,:2
5Programmed cell death of retinal ganglion cells during experimental glaucoma 显示文摘Garcia VE Shareef S Walsh J 1995Exp Eye Res1995,61,:2
6An assessment of the metabolic activity of starved and vegetative bacteria using two redox dyes显示文摘S Walsh H M Lappin-scott L E Stockda 1995Journal of Microbiological Methods1995,,24:1
7A study of quality of life inprimigravidae with urinary incontinence显示文摘Dolan LM Walsh D Hamilton S 2004Int Urogynecol J PelvicFloor Dysfunct2004,15,3:1
8Effects of raloxifene on serum lipids and coagulation factors in healthy postmenopausal women显示文摘 Kuller LH Paul S 1998JAMA1998,279,18:1
9Complication Rates among Cancer Patients with Peripherally Inserted Central Catheters显示文摘Walshe L J Malak S F Eagan J 2002J Clin Oncol2002,20,15:1
10STRO-1,HOP-26 (CD63),CD49a and SB-10(CD166) as markers of primitive human marrow stromal cells and their differentiated progeny: a comparative investigation in vitro 显示文摘Stewart K Monk P Walsh S 2003Cell Tissue Res2003,313,3:1
11Controlled release of platelet-derived growth factor using ethylene vinyl acetate copolymer(EVAc)coated on stainless-steel wires显示文摘Walsh W R Kim H D Jong Y S 1995Biomaterials1995,16,17:1
12Chelex 100 as a medium for simple extraction of DNA for PCR based typing from forensic material 显示文摘Walsh P S Metzger D A 1991Biotechniques1991,10,4:1
13Orsinal and timed balance measurements:reliability and validity in patients with stroke显示文摘Bahannon RW Walsh S Joseph MC 1996Clinrehabili1996,7,2:1
14Incidence of HNPCC in a population-based study of 1137 consecutive cases of colorectal cancer显示文摘Evans DG Walsh S Jeacock J 1997Br J Surg1997,84,9:1
15Ortho-phthalaldehyde:possible alternative to glutaralde-hyde for high level disinfection显示文摘Walsh S E Maillard J Y Ressell A D 1999Appl Microbiol1999,86,:1
16Chelex 100 as a medium for simple extraction of DNA for PCR based typing from forensic material显示文摘Walsh P S Metzger D A Higuchi R 1991Bio Techniques1991,10,:1
17The effect of subclinical ketosis in early lactation on reproductive performance of postparturn dairy cows显示文摘WALSH R B WALTON J S KELTON D F 2007J Dairy Sci2007,90,6:1
18Osteoblasts and osteoclasts in adult human osteophyte tissue express the mRNAs for insulin-like growth factors I and II and the type1IGF receptor显示文摘MIDDLETON J ARNOTT A WALSH S 1995Bone1995,16,3:1
19Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection 显示文摘Teijaro JR Walsh KB Cahalan S 2011Cell2011,146,6:1
20Over-connected?A qualitative exploration of the relationship between Australian youth and their mobile phones显示文摘WALSH S P WHITE K M YOUNG R M 2008J Adolesc2008,31,1:1
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