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| 1 | Efficacy and safety of tenofovir disoproxil fumarate in pregnancy for the prevention of vertical transmission of HBV infection显示文摘AIM:To evaluate the effects of tenofovir disoproxil fumarate(TDF)use during late pregnancy to reduce hepatitis B virus(HBV)transmission in highly viremic mothers.METHODS:This retrospective study included 45 pregnant patients with hepatitis B e antigen(+)chronic hepatitis B and HBV DNA levels>107copies/mL who received TDF 300 mg/d from week 18 to 27 of gestation(n=21).Untreated pregnant patients served as controls(n =24).All infants received 200 IU of hepatitis B immune globulin(HBIG)within 24 h postpartum and 20μg of recombinant HBV vaccine at 4,8,and 24 wk.Perinatal transmission rate was determined by hepatitis B surface antigen and HBV DNA results in infants at week 28.RESULTS:At week 28,none of the infants of TDFtreated mothers had immunoprophylaxis failure,whereas2(8.3%)of the infants of control mothers had immunoprophylaxis failure(P=0.022).There were no differences between the groups in terms of adverse events in mothers or congenital deformities,gestational age,height,or weight in infants.At postpartum week 28,significantly more TDF-treated mothers had levels of HBV DNA<250 copies/mL and normalized alanine aminotransferase compared with controls(62%vs none,P<0.001;82%vs 61%,P=0.012,respectively).CONCLUSION:TDF therapy during the second or third trimester reduced perinatal transmission rates of HBV and no adverse events were observed in mothers or infants. | Mustafa Kemal Celen Duygu Mert Müzeyyen Ay Tuba Dal Safak Kaya Necmettin Yildirim Serda Gulsun Tunga Barcin Sevgi Kalkanli Mehmet Sinan Dal Celal Ayaz | 2013 | World Journal of Gastroenterology2013，19，48： | 26 |
| 2 | Intratympanie Methylprednisolone for Sudden Sensorineural Hearing Loss 显示文摘 | Kilie R Safak M A Oguz H | 2007 | Otol Neurotol2007，28，3： | 1 |
| 3 | Direct closure of radial forearm free- flap donor sites by double-opposing rhomboid transposition flaps: case report显示文摘 | Aky~rek M Safak T | 2002 | J Reconstr Microsurg2002，18，1： | 1 |
| 4 | Osteocutaneous flap prefabrication based on the principle of vascular induction:An experimental and clinical study显示文摘 | Safak T Akyurek M | 2000 | Plast Reconstr Surg2000，105，4： | 1 |
| 5 | Cell cycle regulation of NF-κB- binding activity in cells from human glioblastomas 显示文摘 | Ansari SA Safak M Valle LD | 2001 | Exp Cell Res2001，265，2： | 1 |
| 6 | Susceptibility of red blood cell lipids to in vitro oxidation and antioxidant status in preeclampsia显示文摘 | Dirican M Safak 0 Uncu G | 2008 | EurJ Obstet Gynecol Reprod Bioi2008，140，2： | 1 |
| 7 | Arterialized venous dorsal digital island flap for fingertip reconstruction显示文摘 | Kayikcioglu A Akyurek M Safak T | 1998 | Plast Reconstr Surg1998，102，： | 1 |
| 8 | Nephrostomy tract dilation using a balloon dilator in percutaneous renal surgery: experience with 95 cases and comparison with the fascial dilator system显示文摘 | SAFAK M GOGUS C SOYGUR T | 2003 | Urol Int2003，71，4： | 1 |
| 9 | A new flap design:neural-island flap显示文摘 | Akyürek M Safak T Sonmez E | | 0，，06： | 1 |
| 10 | Regulation of MCP-1 gene transcription by Smads and HIV-1 Tat in human glial cells显示文摘 | Abraham S Sawaya BE Safak M | 2003 | Virology2003，30，9： | 1 |
| 11 | Oxidizability of apolipoprotein B-containing lipoproteins and serum paraoxonase/arylesterase activities in preeclampsia显示文摘 | SARAND(O)L E SAFAK O DIRICAN M | 2004 | Clin Biochem2004，37，11： | 1 |
| 12 | An overview: Human polyomavirus JC virus and its associated disorders显示文摘 | Safak M Khalili K | 2003 | J Neurovirol2003，9，1： | 1 |
| 13 | The evaluation of food hygiene knowledge,attitudes,and practices of food handlers' in food businesses in Turkey显示文摘 | BaS M Safak Ersun A KIvan?G | | 0，，04： | 1 |
| 14 | Nephrostomy tract dilation using a balloon dilator in percutaneous renal surgery:experience with 95cases and comparison with the fascial dilator system显示文摘 | Safak M Gogus C Soygur T | 2003 | Urol Int2003，71，： | 1 |
| 15 | Fingertip replantation at or distal to the nail base: use of the technique of artery-only anastomosis 显示文摘 | Akyurek M Safak T Kecik A | 2001 | Ann Plast Surg2001，46，6： | 1 |
| 16 | Nephrostomy tract dilation using a balloon dilator in percutaneous renal surgery:experience with 95 cases and comparison with the fascial dilator system显示文摘 | Safak M Gogtis C Soygllr T | 2003 | Urol Int2003，71，4： | 1 |
| 17 | Nephrostomy tract dilation using a balloon dilator in percutaneous renal surgery:experience with 95 cases and comparison with the fascial dilator system 显示文摘 | Safak M Gogus C Soygur T | 2003 | UrolIut2003，71，4： | 1 |
| 18 | Nephrostomy tract dilation using a balloon dilator in percutaneous renal surgery:experience with 95 cases and comparison with the fascial dilator system显示文摘 | Safak M Gogus C Soygur T | 2003 | Urol Int2003，71，4： | 1 |
| 19 | Nephrostomy tract dilation using a balloon dilator in percutaneous renal surgery:experience with 95cases and comparison with the fascial dilator system显示文摘 | Safak M GgüC Soygür T | 2013 | Urol Int2013，71，4： | 1 |
| 20 | Coverage of a thumb wound and correction of a first wed space contracture using a longitudinally split reverse radial forearm flap显示文摘 | Akyurek M Safak T Kecik A | 2001 | Ann Plast Surg2001，47，4： | 1 |
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