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| 1 | 肠道微生态失调与高血压的关系显示文摘新出现的证据表明,肠道菌群是维持生理动态平衡的关键,该研究旨在验证微生态失衡的肠道菌群与高血压相关这一假设,因为遗传、环境和膳食因素对肠道菌群和血压有很大影响。方法:从2种高血压模型大鼠和一个小队列患者人群的粪便样本中提取细菌DNA,用于细菌基因组的分析. | 刘莉 叶鹏 Yang T Santisteban MM Rodriguez V Li E Ahmari N Carvajal JM Zadeh M Gong M Qi Y Zubcevic J Sahay B Pepine CJ Raizada MK Mohamadzadeh M | 2015 | 中华高血压杂志2015，23，5： | 4 |
| 2 | Multi-institutional retrospective analysis of FOLFIRI in patients with advanced biliary tract cancers显示文摘BACKGROUND Gemcitabine plus platinum is the standard of care first-line treatment for advanced biliary tract cancers(BTC).There is no established second-line therapy,and retrospective reviews report median progression-free survival(PFS)less than 3 mo on second-line therapy.5-Fluorouracil plus irinotecan(FOLFIRI)is a commonly used regimen in patients with BTC who have progressed on gemcitabine plus platinum,though there is a paucity of data regarding its efficacy in this population.AIM To assess the efficacy of FOLFIRI in patients with biliary tract cancers.METHODS We retrospectively identified patients with advanced BTC who were treated with FOLFIRI at MD Anderson,University of Michigan and Mayo Clinic in Jacksonville.Data were collected on patient demographics,BTC subtype,response per RECIST v1.1,progression and survival.RESULTS Ninety-eight patients were included of which 74(75%)had metastatic and 24(25%)had locally advanced disease at the time of treatment with FOLFIRI.The median age was 60(range,22-86)years.The number of patients with extrahepatic cholangiocarcinoma,gall bladder cancer and intrahepatic cholangiocarcinoma were 10,17 and 71,respectively.FOLFIRI was used as 1st,2nd,3rd or 4th–Nth lines in 8,50,36 and 4 patients,respectively.Median duration on FOLFIRI in the entire cohort was 2.2(range,0.5-8.4)mo.The median PFS and overall survival were 2.4(95%confidence interval(CI):1.7-3.1)and 6.6(95%CI:4.7-8.4)mo,respectively.Median PFS for patients treated with FOLFIRI in 1st,2nd,3rd or 4th–Nth lines were 3.1,2.5,2.3 and 1.5 mo,respectively.Eighteen patients received concurrent bevacizumab(n=13)or EGFR-targeted therapy(n=5)with FOLFIRI,with a median PFS of 2.7 mo(95%CI:1.7-5.1).CONCLUSION In this largest multi-institution retrospective review of 98 patients with BTC treated with FOLFIRI,efficacy appears to be modest with outcomes similar to other cytotoxic chemotherapy regimens. | Jonathan D Mizrahi Valerie Gunchick Kabir Mody Lianchun Xiao Phanikeerthi Surapaneni Rachna T Shroff Vaibhav Sahai | 2020 | World Journal of Gastrointestinal Oncology2020，12，1： | 2 |
| 3 | Aircraft spin recovery, with and without thrust vectoring, using nonlinear dynamic inversion显示文摘 | RAGHAVENDRA P K SAHAI T KUMAR P A | 2005 | Journal of Aircraft2005，42，6： | 1 |
| 4 | Melt Flow Characterization in Continuous Casting Tundishes显示文摘 | SAHAI Y EMI T | 1996 | ISIJ International1996，36，6： | 1 |
| 5 | Melt Flow Characterization in Continuous Casting Tundish 显示文摘 | Sahai Y Emi T | 1996 | ISIJ International1996，36，6： | 1 |
| 6 | Melt Flow Characterization in Continuous Casting Tundishes显示文摘 | | 1996 | ISIJ Intern1996，36，6： | 1 |
| 7 | Neonatal screening for inborn errors of metabolism using tandem mass spectrometry:expe- rience of the pilot study in Andhra Pradesh, India 显示文摘 | Sahai I Zytkowicz T Rao Kotthuri S | 2011 | Indian J Pediatr2011，78，8： | 1 |
| 8 | Melt Flow Characterization in Continuous Casting Tundishes显示文摘 | Sahai Y Emi T | 1996 | ISIJ International1996，36，6： | 1 |
| 9 | Melt Flow Characterization in Continuous Casting Tundishes 显示文摘 | Sahai Y Emi T | 1996 | ISIJ International1996，36，6： | 1 |
| 10 | Melt Flow Characterization in Continuous Casting Tundishes显示文摘 | Sahai Y Emi T | 1996 | ISIJ International1996，36，6： | 1 |
| 11 | Continuous dynamic recrystallization during the transient severe de- formation of aluminum alloy 7475 显示文摘 | SAHAI T MIURA H GOLOBORODKO A | 2009 | Acta Mater2009，57，： | 1 |
| 12 | Melt flow characterization in continuous casting tundishes显示文摘 | Sahai Y Emi T | 1996 | ISIJ Int1996，36，6： | 1 |
| 13 | Strance performance im- provement through use of asymmetric baffles in tundish of six strand billet caster at DSP显示文摘 | Sahay S K De T K Basu D S | 2001 | Iron and Steel2001，，7： | 1 |
| 14 | Quantifying the iceberg effect for injury显示文摘 | Sahai VS Ward MS Zmijowskyj T | 2005 | Canadian Journal of Public Health2005，96，5： | 1 |
| 15 | Melt Flow Characterization in Continuous Casting Tundishes 显示文摘 | Sahai Y Emi T | 1996 | ISIJ International1996，36，6： | 1 |
| 16 | Spectral response of rice cropand its relation to yield and yield attributs显示文摘 | PATEL N K SINGH T P SAHAI B | 1985 | International Journal ofRemote Sensing1985，6，5： | 1 |
| 17 | Melt flow characterization in continuous casting tundishes显示文摘 | Sahai Y Emi T | 1996 | ISIJ International1996，36，6： | 1 |
| 18 | Melt flow characterization in continuous casting tundishes显示文摘 | Sahai Y Emi T | | 0，，06： | 1 |
| 19 | Seismic wave propagation in inhomogeneous and anisotropic porous media显示文摘 | Sahay P N Spanos T J T Cruz V de la | 1995 | Geophysical Journal International1995，145，： | 1 |
| 20 | Melt flow characterization in continuous casting tundish 显示文摘 | Sahai Y Emi T | 1996 | IS1J international1996，36，6： | 1 |
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