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| 1 | Hepatocellular carcinoma in non-alcoholic steatohepatitis:Current knowledge and implications for management显示文摘With the prevalence of hepatitis C virus expected to decline, the proportion of hepatocellular carcinoma(HCC) related to non-alcoholic steatohepatitis(NASH) is anticipated to increase exponentially due to the growing epidemic of obesity and diabetes. The annual incidence rate of developing HCC in patients with NASH-related cirrhosis is not clearly understood with rates ranging from 2.6%-12.8%. While multiple new mechanisms have been implicated in the development of HCC in NASH; further prospective long-term studies are needed to validate these findings. Recent evidence has shown a significant proportion of patients with non-alcoholic fatty liver disease and NASH progress to HCC in the absence of cirrhosis. Liver resection and transplantation represent curative therapeutic options in select NASHrelated HCC patients but have placed a significant burden to our healthcare resources and utilization. Currently NASH-related HCC is the fastest growing indication for liver transplant in HCC candidates. Increased efforts to implement effective screening and preventative strategies, particularly in non-cirrhotic NASH patients, are needed to reduce the future impact imposed by NASH-related HCC. | George Cholankeril Ronak Patel Sandeep Khurana Sanjaya K Satapathy | 2017 | World Journal of Hepatology2017,9,11: | 12 |
| 2 | 天疱疮患者206例皮损分泌物病原学及药敏结果分析显示文摘目的分析天疱疮患者糜烂面皮损的病原菌组成及药敏情况,为临床早期合理选用抗生素提供依据。方法对本科2004年1月-2011年12月收治的206例天疱疮患者皮损分泌物细菌培养和药敏结果进行回顾性分析。结果分离出细菌200株中,金黄色葡萄球菌107株,耐甲氧西林金黄色葡萄球菌11株;50%以上金黄色葡萄球菌对青霉素、红霉素、克林霉素耐药,100%对万古霉素敏感,80%以上对利福平、复方新诺明敏感;29例多部位取材共检出病原菌53株。结论天疱疮糜烂面细菌主要由金黄色葡萄球菌构成,多数对青霉素、红霉素及克林霉素耐药,对万古霉素、利福平和复方新诺明敏感;病程长且多次就诊者易感染耐甲氧西林金黄色葡萄球菌;抗生素早期使用可参考皮损主要累及部位及该部位常见定植菌种类选择。 | 郭生红 王琳 李明辉 Sanjaya Shakya 杨延华 张然 康梅 李薇 | 2012 | 中国皮肤性病学杂志2012,26,11: | 9 |
| 3 | Reactivation of hepatitis B after liver transplantation: Current knowledge, molecular mechanisms and implications in management显示文摘Chronic hepatitis B(CHB) is a major global health problem affecting an estimated 350 million people with more than 786000 individuals dying annually due to complications, such as cirrhosis, liver failure and hepatocellular carcinoma(HCC). Liver transplantation(LT) is considered gold standard for treatment of hepatitis B virus(HBV)-related liver failure and HCC. However, post-transplant viral reactivation can be detrimental to allograft function, leading to poor survival. Prophylaxis with high-dose hepatitis B immunoglobulin(HBIG) and anti-viral drugs have achieved remarkable progress in LT by suppressingviral replication and improving long-term survival. The combination of lamivudine(LAM) plus HBIG has been for many years the most widely used. However, life-long HBIG use is both cumbersome and costly, whereas long-term use of LAM results in resistant virus. Recently, in an effort to develop HBIG-free protocols, high potency nucleos(t)ide analogues, such as Entecavir or Tenofovir, have been tried either as monotherapy or in combination with low-dose HBIG with excellent results. Current focus is on novel antiviral targets, especially for covalently closed circular DNA(ccc DNA), in an effort to eradicate HBV infection instead of viral suppression. However, there are several other molecular mechanisms through which HBV may reactivate and need equal attention. The purpose of this review is to address post-LT HBV reactivation, its risk factors, underlying molecular mechanisms, and recent advancements and future of anti-viral therapy. | Ranjit Chauhan Shilpa Lingala Chiranjeevi Gadiparthi Nivedita Lahiri Smruti R Mohanty Jian Wu Tomasz I Michalak Sanjaya K Satapathy | 2018 | World Journal of Hepatology2018,10,3: | 5 |
| 4 | 线状IgA大疱性皮病15例分析显示文摘目的分析线状IgA大疱性皮病的临床特点、治疗及预后,提高临床医生对本病的认识。方法回顾性分析本科2004年1月-2011年12月诊治的15例线状IgA大疱性皮病的临床资料。结果男6例,女9例;儿童型5例,成人型10例;皮损初始部位:面部4例,口腔黏膜及双下肢各3例;累及躯干和四肢12例,14例临床表现为红斑或正常皮肤上出现水疱,6例水疱呈环形或半环形排列。皮损组织病理均见表皮及复层鳞状上皮下水疱或裂隙,直接免疫荧光均表现为基底膜带线状IgA沉积。13例予糖皮质激素治疗,皮损均控制;2例予氨苯砜治疗,均发生不良反应。结论线状IgA大疱性皮病的皮损以口腔黏膜、面部及下肢首发居多,好发于躯干和四肢,临床表现为红斑或正常皮肤上出现水疱,呈孤立、环形和/或半环形排列;组织病理可见表皮或复层鳞状上皮下水疱或裂隙,直接免疫荧光示基底膜带线状IgA沉积是诊断的主要依据。治疗上可选用氨苯砜、糖皮质激素和磺胺类药物等。 | 郭生红 Sanjaya Shakya 李薇 王琳 杜晓萍 | 2012 | 中国皮肤性病学杂志2012,26,10: | 4 |
| 5 | 慢性家族性良性天疱疮16例临床与病理分析显示文摘目的探讨慢性家族性良性天疱疮(CFBP)的临床、病理学特点,以提高对本病的认识。方法分析经病理学确诊的16例CFBP的临床资料、组织病理及治疗。结果男10例,女6例,平均年龄37.8岁,平均病程10.56年,发病年龄3~52岁;7例有家族史。皮损好发于腹股沟、腋窝、肛周,泛发者1例;表现为在红斑/外观正常皮肤上出现水疱或丘疹伴糜烂渗液,呈扁平柔软、湿润增殖面;1例合并银屑病。组织病理学检查16例均见棘层松解如倒塌砖墙样,11例伴角化过度、松解上方灶性角化不全,13例见角化不良细胞,9例角质层/棘层上部见圆体,5例见谷粒,12例见棘层松解边缘棘层肥厚及表皮突延长;直接免疫荧光检查均阴性。口服小剂量强的松等治疗约2周可以改善临床症状,但易反复。结论本病病程长,43.75%有阳性家族史,临床易误诊为湿疹或增殖型天疱疮,组织病理学检查发现倒塌砖墙样棘层松解及直接免疫荧光检查为阴性有诊断及鉴别诊断价值,但缺乏有效治疗。 | 郭生红 李薇 Sanjaya Shakya 王琳 杜晓萍 | 2012 | 中国皮肤性病学杂志2012,26,8: | 3 |
| 6 | Non-alcoholic fatty liver and chronic kidney disease:Retrospect,introspect,and prospect显示文摘With the growing prevalence of obesity and diabetes in the United States and across the world,a rise in the overall incidence and prevalence of non-alcoholic fatty liver disease(NAFLD)is expected.The risk factors for NAFLD are also associated with the development of chronic kidney disease(CKD).We review the epidemiology,risk factors,genetics,implications of gut dysbiosis,and specific pathogenic mechanisms linking NAFLD to CKD.Mechanisms such as ectopic lipid accumulation,cellular signaling abnormalities,and the interplay between fructose consumption and uric acid accumulation have led to the emergence of potential therapeutic implications for this patient population.Transplant evaluation in the setting of both NAFLD and CKD is also reviewed.Potential strategies for surveillance and management include the monitoring of comorbidities,the use of non-invasive fibrosis scoring systems,and the measurement of laboratory markers.Lastly,we discuss the management of patients with NAFLD and CKD,from preventative measures to experimental interventions. | Rajiv Heda Masahiko Yazawa Michelle Shi Madhu Bhaskaran Fuad Zain Aloor Paul J Thuluvath Sanjaya K Satapathy | 2021 | World Journal of Gastroenterology2021,27,17: | 3 |
| 7 | Polynomial friction pendulum isolators(PFPIs)for seismic performance control of benchmark highway bridge显示文摘The seismic response of a benchmark highway bridge isolated with passive polynomial friction pendulum isolators(PFPIs)is investigated and subjected to six bidirectional ground motion records.The benchmark study is based on a lumped mass finite-element model of the 91/5 highway overcrossing located in Southern California.The PFPI system possesses two important parameters;one is horizontal flexibility and the other is energy absorbing capacity through friction.The evaluation criteria of the benchmark bridge are analyzed considering two parameters,time period of the isolator and coefficient of friction of the isolation surface.The results of the numerical study are compared with those obtained from the traditional friction pendulum system(FPS).Dual design performance of the PFPI system suppressed the displacement and acceleration response of the benchmark highway bridge.The dual design hysteresis loop of the PFPI system is the main advantage over the linear hysteresis loop of the FPS.The numerical result indicates that the seismic performance of the PFPI system is better than that of the traditional FPS isolated system.Further,it is observed that variations of the isolation time period and coefficient of friction of the FPS and PFPI systems have a significant effect on the peak responses of the benchmark highway bridge. | Arijit Saha Pumachandra Saha Sanjaya Kumar Patro | 2017 | Earthquake Engineering and Engineering Vibration2017,16,4: | 3 |
| 8 | 疱疹样皮炎1例显示文摘1病历摘要
患者男,71岁。全身反复红斑、丘疹、水疱伴剧烈瘙痒10个月。10个月前患者无明显诱因双胫前出现弥漫绿豆至蚕豆大、形状不规则边缘模糊的红斑。部分红斑上密集针尖大丘疹.散在芝麻至绿豆大孤立厚壁张力性清亮水疱,不易破溃, | 郭生红 Sanjaya Shakya 贾玲 闫薇 李薇 | 2013 | 临床皮肤科杂志2013,42,9: | 3 |
| 9 | Influence of non‐alcoholic fatty liver disease on the development of diabetes mellitus显示文摘 | Anuradhani Kasturiratne Sanjaya Weerasinghe Anuradha S Dassanayake Shaman Rajindrajith Arjuna P Silva Norihiro Kato A Rajitha Wickremasinghe H Janaka Silva | 2012 | J Gastroenterol Hepatol2012,,1: | 2 |
| 10 | Liver injury in COVID-19:The hepatic aspect of the respiratory syndrome-what we know so far显示文摘The 2019 novel coronavirus disease(COVID-19)pandemic due to severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has posed a serious threat to global public health.Although primarily,the infection causes lung injury,liver enzyme abnormalities have also been reported to occur during the course of the disease.We conducted an extensive literature review using the PubMed database on articles covering a broad range of issues related to COVID-19 and hepatic injury.The present review summarizes available information on the spectrum of liver involvement,the possible mechanisms and risk factors of liver injury due to SARS-CoV-2 infection,and the prognostic significance of the presence of liver injury.Hopefully,this review will enable clinicians,especially the hepatologists,to understand and manage the liver derangements they may encounter in these patients better and provide guidance for further studies on the liver injury of COVID-19. | Prajna Anirvan Pankaj Bharali Mrinal Gogoi Paul J Thuluvath Shivaram P Singh Sanjaya K Satapathy | 2020 | World Journal of Hepatology2020,12,12: | 2 |
| 11 | 成人传染性单核细胞增多症1例显示文摘患者男,30岁。面、项部红斑、丘疹伴瘙痒15d,泛发全身13d。体检:T37.4℃,全身浅表淋巴结肿大,咽充血,咽腭弓瘀点,双侧扁桃体I°肿大。皮肤科情况:头部散在分布红斑;项部密集分布丘疹、斑丘疹,融合成斑块;颈部、躯干、四肢丘疹及暗红斑,双小腿伸侧散在紫癜;掌、跖部暗红斑,肿胀明显,轻触痛。外周血异形淋巴细胞8%,血生化示肝酶升高,EB病毒抗体阳性,彩色多普勒检查示脾大。诊断:成人传染性单核细胞增多症。经地塞米松等治疗,患者痊愈。 | 郭生红 杨延华 Sanjaya Shakya 王婷婷 李薇 | 2012 | 中国皮肤性病学杂志2012,26,12: | 2 |
| 12 | 表现为环形红斑水疱的疱疹样皮炎1例显示文摘患者女,46岁。全身反复红斑、水疱伴痒6年,加重20d。皮损组织病理示:表皮下水疱,其内中性粒细胞聚集成小脓肿,真皮内散在淋巴细胞浸润。皮损边缘组织直接免疫荧光示:真皮乳头浅层纤维素样IgA,IgM,C3沉积。诊断:疱疹样皮炎。予糖皮质激素、四环素等治疗好转出院。随访3年无复发,目前仍在随访中。 | 夏登梅 郭生红 Sanjaya Shakya 侯文婕 闫薇 李薇 | 2013 | 中国皮肤性病学杂志2013,27,7: | 2 |
| 13 | India's Manufactured Exports: Comparative Structure and Prospects显示文摘 | Sanjaya Lall | 1999 | World Development1999,,10: | 1 |
| 14 | Employment and foreign investment:Policy options for developing countries 显示文摘 | Sanjaya Lall | 1995 | international labour review1995,,45: | 1 |
| 15 | 'Market-Stimulating' technology policies in developing countries: A framework with ex- amples from East Asia显示文摘 | Sanjaya L Teubal M | 1998 | World Development1998,26,8: | 1 |
| 16 | The Sophistication of Export A New Trade Measure 显示文摘 | Lall Sanjaya John Weiss and Zhang Jin kang | 2006 | World Development2006,,34: | 1 |
| 17 | Prolongation of the QTc Interval Is Seen Uniformly During Early Transmural Ischemia显示文摘 | David N. Kenigsberg Sanjaya Khanal Marcin Kowalski Subramaniam C. Krishnan | 2007 | Journal of the American College of Cardiology2007,,: | 1 |
| 18 | Directional Antenna Multipath Location Aided Routing(DA-MLAR)显示文摘 | SANJAYA G WANGT Limin BEHNAM M | 2006 | IEEE2006,,05: | 1 |
| 19 | The Technological Structure andPerformance of Developing Country Manufactured Exports:1985~98显示文摘 | SANJAYA LALL | 2000 | Oxford development studies2000,28,3: | 1 |
| 20 | The Technological Sturcture and Performance of Developing Country M anufactured Exports显示文摘 | Lall Sanjaya | 2000 | Oxoford Development Studies2000,28,3: | 1 |