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    题名 作者 年代 出处 被引量
1miR-328 Functions as an RNA Decoy to Modulate hnRNP E2 Regulation of mRNA Translation in Leukemic Blasts显示文摘Anna M. Eiring Jason G. Harb Paolo Neviani Christopher Garton Joshua J. Oaks Riccardo Spizzo Shujun Liu Sebastian Schwind Ramasamy Santhanam Christopher J. Hickey Heiko Becker Jason C. Chandler Raul Andino Jorge Cortes Peter Hokland Claudia S. Huettner Ra 2010Cell2010,,5:2
2刀具创新对提高金属切削效率的作用与影响显示文摘世界范围内激烈的市场竞争迫使机械制造业降低成本以保持盈利。由于加工成本的主要部分是占用机床时间的费用,因此目前人们的注意力集中在通过提高加工生产率以缩短加工周期。机床的改进,性能更优异的零件材料的开发,新的加工方法的开发以及涉及切削液安全处理的环保法规的制订等,都给刀具行业带来了新的挑战。为了回应这些挑战,刀具行业对各种刀具材料进行了卓有成效的创新。本文重点讨论刀具技术的进步对提高金属切削生产率所起的作用。M S Greenfield A T Santhanam 胡红兵 2005工具技术2005,,12:2
3polyketide and benzopyran compounds of an endophytic fungus isolated from Cinnamomum mollissimum:biological activity and structure显示文摘Objective:To study bioactivity and compounds produced by an endophytic Phoma sp.fungus isolated from the medicinal plant Cinnamomum mollissimum.Methods:Compounds produced by the fungus were extracted from fungal broth culture with ethyl acetate.This was followed by hioaclivity profiling of the crude extract fractions obtained via high performance liquid chromatography.The fractions were tested for cytotoxicity to P388 murine leukemic cells and antimicrobial activity against bacteria and pathogenic fungi.Compounds purified from active fractions which showed antibacterial,antifungal and cytotoxic activities were identified using capillary nuclear magnetic resonance analysis,mass spectrometry and admission to AntiMarin database.Results:Three known compounds,namely 4—hydroxymellein,4,8—dihydroxy—6—melhoxy—3—methyl—3,4-dihydro—1H-isochromen-1—one and 1—(2,6-dihydroxyphenyl) ethanone,were isolated from the fungus.The polyketide compound 4—hydroxymellein showed high inhibitory activity against P388 murine leukemic cells(94.6%) and the bacteria Bacillus sublilis(97.3%).Meanwhile.4,8—dihydroxy-6—melhoxy—3—meth) 1—3,4-dihydro—1H—isochromen—1-one,a benzopyran compound,demonstrated moderate inhibitory activity against P388 murine leukemic cells(48.8%)and the fungus Aspergillus niger(56.1%).The second polyketide compound.1(2,6—dihydroxyphenyl)ethanone was inactive against the tested targets.Conclusions:These findings demonstrate the potential of endophytes as producers ol pharmacologically important compounds,including polyketides which are major secondary metabolites in fungi.Carolina Santiago Lin Sun Murray Herbert Gibson Munro Jacinta Santhanam 2014Asian Pacific Journal of Tropical Biomedicine2014,4,8:2
4Influence of two different dietary zinc sources in freshwater prawn Macrobrachium rosenbergii post larvae显示文摘A feeding experiment was conducted to evaluate the ef fects of bulk zinc(B-Zn) and zinc nanoparticles(Zn-NPs) on survival, growth, compositions of amino acid and fatty acid, and nonspeci?c immune responses of the freshwater prawn, Macrobrachium rosenbergii post larvae. The B-Zn(size 10 μm)and Zn-NPs(size 50 nm) were supplemented separately with the basal feeds of M. rosenbergii at 60 mg/kg and feed without supplementation of any Zn source was served as a control. M. rosenbergii were fed these feeds for 90 days and the results showed that signi?cant( P <0.05) improvements in survival, growth, feed intake,speci?c growth rate, essential amino acids, unsaturated fatty acids, nonspeci?c immune responses(total haemocytes and dif ferential haemocytes count) of M. rosenbergii fed with B-Zn and Zn-NPs supplemented feeds when compared to control. Among these Zn sources, Zn-NPs supplemented feeds fed prawns showed signi?cantly( P <0.05) better performance than that of B-Zn and control. Hence, present study suggests that the 60 mg/kg Zn-NPs can be supplemented with basal feeds of M. rosenbergii for regulating better survival and growth.THIRUNAVUKKARASU Muralisankar PERIYAKALI Saravana Bhavan SUBRAMANIAN Radhakrishnan PERUMAL Santhanam 2019Journal of Oceanology and Limnology2019,37,1:2
5Improved charge transfer at carbon nanotube electrodes显示文摘Britto P J Santhanam KSV Rubio A 1999Adv Mater1999,,11:1
6FTY720 demonstrates promising preclinical activity for chronic lymphocytic leukemia and lymphoblastic leukemia/lymphoma 显示文摘Liu Q Zhao X Frissom F Ma Y Santhanam R Jarjoura D 2008Blood2008,,1:1
7Carbon nanotube electrode for oxidation of dopamine显示文摘P J BRITTO K S V SANTHANAM P M AJAYAN 1996Bioelectrochemistry and Bioenergetics1996,41,:1
8Nucleation and growth mechanicsm of electroformation of polypyrrole on a heat-treated gold/highly oriented pyrolytic graphite 显示文摘HWANG BING JOE SANTHANAM RAMAN LIN YI LIANG 2001Electrochimica Acta2001,46,:1
9AMAPK/HNRPK pathway controls BCR/ABL oncogenic potential by regulating MYC mRNA translatlon显示文摘Notarl M Neviani P Santhanam R 2006Blood2006,107,6:1
10Multicomponent AM-FM demodulation via periodicity-based algebraic separation and energy-based demodulation显示文摘Santhanam B Maragos P 0,,03:1
11Cohen, Jan Olek ,Mechanism of sulfate attack: A fresh look显示文摘Manu Santhanam Menashi D 2002Cement and Concrete Research2002,32,:1
12Electrochemically active polymers for rechargeable batteries显示文摘Nova P Muller K Santhanam K 1997Chemical Review1997,97,:1
13Effect of synthesis conditions on electrochemical properties of LiNi1-yCoyO2 cathode for lithium rechargeable batteries 显示文摘Hwang B J Santhanam R Chen C H 2003Journal of Power Sources2003,114,:1
14Catalytic oxidation of p-toluidine at multiwalled ftmctionalized carbon nanotubes 显示文摘Croston M Langston J Sangoi R Santhanam K S V 2002International Journal of Nanoscience2002,1,34:1
15The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein 显示文摘Neviani P Santhanam R Trotta R 2005Cancer Cell2005,8,5:1
16A decision model for interdependent information system project selection显示文摘Santhanam R Kyparisis J 1996Europen Journal of Operational Research1996,,89:1
17New borohydride fuel cell with muhiwalled carbon nanotubes as anode:A step towards increasing the power output 显示文摘Deshmukh K Santhanam K S V J 2006J Power Sources2006,159,:1
18Efects of gypsum formation on the performance of cement mortars during external sulphate attack 显示文摘Manu Santhanam Menashi D Cohen Jan Olek 2003Cem and Concr Res2003,33,:1
19Resonant carrierscattering by core-shell nanoparticles for thermoelectricpower factor enhancement显示文摘Bahk J H Santhanam P Bian Z 2012Applied Physics Letters2012,100,01:1
20A high-per- formance brain-computer interface 显示文摘SANTHANAM G RYU S I YU B M 2006Nature2006,442,7099:1
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