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| 1 | Gut bless you:The microbiota-gut-brain axis in irritable bowel syndrome显示文摘Irritable bowel syndrome(IBS)is a common clinical label for medically unexplained gastrointestinal symptoms,recently described as a disturbance of the microbiota-gut-brain axis.Despite decades of research,the pathophysiology of this highly heterogeneous disorder remains elusive.However,a dramatic change in the understanding of the underlying pathophysiological mechanisms surfaced when the importance of gut microbiota protruded the scientific picture.Are we getting any closer to understanding IBS’etiology,or are we drowning in unspecific,conflicting data because we possess limited tools to unravel the cluster of secrets our gut microbiota is concealing?In this comprehensive review we are discussing some of the major important features of IBS and their interaction with gut microbiota,clinical microbiota-altering treatment such as the low FODMAP diet and fecal microbiota transplantation,neuroimaging and methods in microbiota analyses,and current and future challenges with big data analysis in IBS. | Eline Margrete Randulff Hillestad Aina van der Meeren Bharat Halandur Nagaraja Ben RenéBjørsvik Noman Haleem Alfonso Benitez-Paez Yolanda Sanz Trygve Hausken Gülen Arslan Lied Arvid Lundervold Birgitte Berentsen | 2022 | World Journal of Gastroenterology2022，28，4： | 15 |
| 2 | Gut microbiota-related complications in cirrhosis显示文摘Gut microbiota plays an important role in cirrhosis. The liver is constantly challenged with commensal bacteria and their products arriving through the portal vein in the so-called gut-liver axis. Bacterial translocation from the intestinal lumen through the intestinal wall and to mesenteric lymph nodes is facilitated by intestinal bacterial overgrowth, impairment in the permeability of the intestinal mucosal barrier, and deficiencies in local host immune defences. Deranged clearance of endogenous bacteria from portal and systemic circulation turns the gut into the major source of bacterialrelated complications. Liver function may therefore be affected by alterations in the composition of the intestinal microbiota and a role for commensal flora has been evidenced in the pathogenesis of several complications arising in end-stage liver disease such as hepatic encephalopathy, splanchnic arterial vasodilatation and spontaneous bacterial peritonitis. The use of antibioticsis the main therapeutic pipeline in the management of these bacteria-related complications.However,other strategies aimed at preserving intestinal homeostasis through the use of pre-,pro-or symbiotic formulations are being studied in the last years.In this review,the role of intestinal microbiota in the development of the most frequent complications arising in cirrhosis and the different clinical and experimental studies conducted to prevent or improve these complications by modifying the gut microbiota composition are summarized. | Isabel Gómez-Hurtado José Such Yolanda Sanz Rubén Francés | 2014 | World Journal of Gastroenterology2014，20，42： | 12 |
| 3 | Protective effect of Bifidobacterium pseudocatenulatum CECT 7765 against induced bacterial antigen translocation in experimental cirrhosis显示文摘 | Alba Moratalla Isabel Gómez‐Hurtado Arlette Santacruz ángela Moya Gloria Peiró Pedro Zapater José M. González‐Navajas Paula Giménez José Such Yolanda Sanz Rubén Francés | 2014 | Liver Int2014，，6： | 2 |
| 4 | Defini-tion of relapse risk and role of nonanthracycline drugsfor consolidation in patients with acute promyelocyticleukemia: A joint study of the PETHEMA andG1MEMA cooperative groups 显示文摘 | SANZ M A LO COCO F MARTIN G | 2000 | Blood2000，96，： | 1 |
| 5 | Biosynthesis of strawberry aroma compounds through amino acid metabolism显示文摘 | Perez A G Olias R Luaces P Sanz C | 2002 | Journal of Agricultural and Food Chemistry2002，50，14： | 1 |
| 6 | A modified AIDA protocol with anthracycline-based consolidation results in high antileukemic efficacy and reduced toxicity in newly diagnosed PML/RA Ralpha-positive acute promyelocytic leukemia显示文摘 | Sanz M A Martín G Rayón C | 1999 | PETHEMA group Blood1999，94，9： | 1 |
| 7 | Hydroperoxide lyase depletion in transgenic potato plants leads to an increase in aphid performance显示文摘 | VANCANNEYT G SANZ C FARMAKI T | 2001 | Proc Nad Acad Sci USA2001，98，14： | 1 |
| 8 | Evolution of strawberry alcohol acyltransferase activity during fruit development and storage显示文摘 | PEREZ A G SANZ C OLIAS R | 1996 | J Agric Food Chem1996，44，10： | 1 |
| 9 | Influence of ingredients on the thermo-rheological behaviour of batters containing methyl- cellulose显示文摘 | Sanz T Salvador A Vlez G | 2005 | Food Hydrocolloids2005，19，5： | 1 |
| 10 | Volatile composition of vinegars simultaneous distillation extraction and gas chromatographicmass spectrometric analysis显示文摘 | Blanch G Tabera J Sanz J | 1992 | Journal Food Chemistry1992，40，6： | 1 |
| 11 | CD34^+ cells from acute myeloid leukemia,myelodysplastic syndromes,and normal bone marrow display different apoptosis and drug resistance-associated phenotypes显示文摘 | Suarez L Vidriales MB Garcia-Larana J Sanz G Moreno MS Lopez A | 2004 | Clin Cancer Res2004，10，22： | 1 |
| 12 | Hydrolysis of porkmuscle sarcoplasmic protoins by Lactobacillus curvaJus andLactobacillus sakei 显示文摘 | Fadda S Sanz Y Vignolo G | 1999 | Applied and Environmental Mi-crobiology1999，65，2： | 1 |
| 13 | Amino functionalized meso- structured SBA-15 silica for COz capture: Exploring the relation be- tween the adsorption capacity and the distribution of amino groups by TEM显示文摘 | Sanz R Calleja G Arencibia A | 2012 | Microp Mesop Mater2012，158，： | 1 |
| 14 | Allergen-induced basophil activation:CD63 cell expression detected by flow cytometry in patients allergic to Dermatophagoides pteronyssinus and Lolium perenne显示文摘 | Sanz M L Sanchez G Gamboa P M | 2001 | Clin Exp AUergy2001，31，7： | 1 |
| 15 | Plif- erative activity of plasma cells is the most relevant prog- nostic factor in elderly multiple myeloma patients 显示文摘 | Garcia Sanz R Gonzalez Fraile M I Mateo G | 2004 | Int J Cancer2004，112，5： | 1 |
| 16 | Effect of high pressure on the reduction of microbial populations in vegetables显示文摘 | ARROYO G SANZ P D PRESTAMO G | 1997 | Journal of Applied Microbiology1997，82，6： | 1 |
| 17 | Effect of graft source on unrelated donor haemopoietic stem-cell transplantation in adults with acute leukaemia:a retrospective analysis显示文摘 | Eapen M Rocha V Sanz G | 2010 | Lancet Oncol2010，11，7： | 1 |
| 18 | Aroma components and free amino acids in strawberry variety Chandler during ripening显示文摘 | Perez A G Rios J J Sanz C Olias J M | 1992 | Journal of Agricultural and Food Chemistry1992，40，11： | 1 |
| 19 | Production and concentration of monoacylglycerols rich in omega - 3 polyun- saturated fatty acids by enzymatic glycerolysis and molecular distillation显示文摘 | Solaesa A G Sanz M T Falkeborg M | 2016 | Food Chemistry2016，190，： | 1 |
| 20 | Disparity for the minor histocompatibility antigen HA-1 is associated with an increased risk of acute graft-versus-host disease(GvHD)but it does not affect chronic GvHD incidence,disease-free survival or overall survival after allogeneic human leucocyte antigen-identical sibling donor transplantation显示文摘 | Arostegui JI Balas A Torres A Caballero D Carreras E Brunet S Jimenez A Mataix R Serrano D Vallejo C Sanz G Solano C Rodriguez-Luaces M Marin J Baro J Sanz C Roman J Gonzalez M Martorell J Sierra J Martin C de la Camara R Granena A | 2001 | Br J Haematol2001，114，4： | 1 |
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