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| 1 | Association of Helicobacter pylori IgA antibodies with the risk of peptic ulcer disease and gastric cancer显示文摘AIM: To compare the prevalence of Helicobacter pylori (Hpylori) IgG and IgA antibodies between adult subjects,with defined gastric diseases, nondefined gastric disorders and those representing the population.METHODS: Data on H pylori IgG and IgA antibodies,determined by enzyme immunoassay, were analyzed in 3 252 subjects with DGD including 482 patients with gastric ulcer, 882 patients with duodenal ulcer, 1 525patients with chronic gastritis only and 363 subjects with subsequent gastric cancer, 19 145 patients with NoDg and4 854 POPUL subjects. The age-adjusted prevalences were calculated for 1- and 20-year age cohorts.RESULTS: The prevalences of IgG antibodies were equally high (89-96%) in all 20-year age cohorts of the DGD groups, whereas the prevalences of IgG antibodies were lower and increased by age in the POPUL and NoDg groups. The prevalences of IgA antibodies were also higher in the DGD groups; among them CA (84-89%) and GU groups (78-91%) showed significantly higher prevalences than DU (68-77%) and CG patients (59-74%) (OR 2.49, 95%CI 1.86-3.34 between the GU and DU groups). In the CA, GU, and DU groups, the IgA prevalences showed only minor variation according to age, while they increased by age in the CG, POPUL, and NoDg groups (P≤0.0001). The IgA response, but not the IgG response, was associated with an increased risk of CA (OR 2.41, 95%CI 1.79-3.53) and GU (OR 2.57,95%CI 1.95-3.39) in comparison with CG patients.CONCLUSION: An IgA antibody response during H pylori infection is significantly more common in CA and GU patients as compared with CG patients. | Timo U Kosunen Kari Seppl Seppo Sarna Arpo Aromaa Paul Knekt Jarmo Virtamo Anniina Salomaa-Rsnen Hilpi Rautelin | 2005 | World Journal of Gastroenterology2005，11，43： | 3 |
| 2 | Smoking,the missing drug interaction in clinical trials:ignoring the obvious显示文摘 | Griz ER Dresler C Sarna L | 2005 | Cancer Epidemiol Biomarkers Prev2005，14，10： | 1 |
| 3 | Correlates of symptom distress in women with lung cancer显示文摘 | Sarna L | 1993 | Cancer Pract1993，1，1： | 1 |
| 4 | Quality of life of long-term survivors of non-small-cell lung cancer 显示文摘 | Sarna L Padilla G Holmes C | 2002 | Journal of Clinical Oncology2002，20，13： | 1 |
| 5 | Clinically meaningful differences in patient-reported out comes with amifostine in combination with chemo radiation for locally advanced non - small - cell lung canc- er;an analysis of RTOG 9801 显示文摘 | L Sarna S swarm CLanger | 2008 | Int J Radiat Oncol Biol Phys2008，72，5： | 1 |
| 6 | Use of complementary and alternative medicine therapies to control symptoms in women living with lung cancer显示文摘 | Wells M Sarna L Cooley ME | 2007 | Cancer Nurs2007，30，1： | 1 |
| 7 | Quality of life of long-term survivors of non-small-cell lung cancer显示文摘 | Sarna L Padilla G Holmes C | 2002 | J Clin Oncol2002，20，13： | 1 |
| 8 | Nurses'Tobacco-relatedKnowledge,Attitudes,and Practice in Four Major Cities in China显示文摘 | Chan S S Sarna L Wong D C | 2007 | Journal of Nursing Scholarship2007，39，： | 1 |
| 9 | Impact of respiratory symptoms and pulmonary function on quality of life of long term survivors of non-small cell lung cancer显示文摘 | Sarna L Evangelistal Tashkin D | 2004 | Chest2004，125，2： | 1 |
| 10 | Effectiveness of structural nursing assessment of symptom distress in advanced lung cancer 显示文摘 | SARNA L | 1998 | Oncol Nuts Forum1998，25，6： | 1 |
| 11 | Correlates of symptom distress in women with lung cancer显示文摘 | Sarna L | 1993 | Cancer Pract1993，1，1： | 1 |
| 12 | Impact of respiratory symptoms and pulmonary function on quality of life of long--term survivors of non- small cell lung cancer显示文摘 | Sarna L Evangel Ista L Tashkin D | 2004 | Chest2004，125，2： | 1 |
| 13 | Quality of life of long term survivors of non-small-cell lung cancer显示文摘 | Sarna L Padilla G Holmes C | 2002 | J Clin Oneol2002，，13： | 1 |
| 14 | Quality of life supersedes the classic prognosticators for long-term survival in locally ad- vanced non-small-cell lung cancer:an analysis of RTOG 980显示文摘 | Movsas B Moughan J Sarna L | 2009 | J Clin oncol2009，27，34： | 1 |
| 15 | The Roles of Neuromelanin, Binding of Metal Ions, and Oxidative Cytotoxi- city in the Pathogenesis of Parkinsonrs Disease: a Hypothesis显示文摘 | Enochs W S Sarna T Zecca L | 1994 | J Neural Transm1994，，7： | 1 |
| 16 | Women with 10ng cancer: quality of life after thoracotomy: a 6 - month prospective study 显示文摘 | Sarna L Cooley ME Brown JK | 2010 | Cancer Nuts2010，33，2： | 1 |
| 17 | Correlates of symptom distress in women with lung canc- er显示文摘 | Sarna L | 1993 | Cancer Pract1993，1，1： | 1 |
| 18 | Nurses' tobacco - related knowledge, attitudes, and practice in 4 major cities in China 显示文摘 | Chart SS Sarna L Wong DC | 2007 | J Nurs Scholarsh2007，39，1： | 1 |
| 19 | Nurses' tobacco-re- lated Knowledge, Attitudes, and Practices in Four Major Cities in China显示文摘 | Chan S S Sarna L Wong D C | 2007 | J Nurs Scholarsh2007，39，1： | 1 |
| 20 | Nurses' tobacco-related knowledge,attitudes,and practice in four major cities in China显示文摘 | Chan SS Sarna L Wong DC | 2007 | J Nurs Scholarsh2007，39，1： | 1 |
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