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| 1 | Value of multi-disciplinary input into laparoscopic management of rectal cancer-An observational study显示文摘AIM To assess the impact of multi-disciplinary teams(MDTs)management in optimising the outcome for rectal cancers.METHODS We undertook a retrospective review of a prospectively maintained database of patients with rectal cancers(defined as tumours≤15 cm from anal verge)discussed at our MDT between Jan 2008 and Jan 2011.The data was validated against the national database to ensure completeness of dataset.The clinical course and follow-up data was validated using the institution’s electronic patient records.The data was analysed in terms of frequencies and percentages.Significance of any differences were analysed usingχ2 test.A Kaplan-Meier analysis was performed for overall survival and disease free survival.RESULTS Following appropriate staging,one hundred and thirtythree patients were suitable for potentially curative resections.Seventy two(54%)were upper rectal cancer(URC)-tumour was>6 cm from the anal verge and 61(46%)were lower rectal cancers(LRC)-lower extent of the tumour was palpable≤6 cm.Circumferential resection margin(CRM)appeared threatened on preoperative MRI in 19/61(31%)patients with LRC requiring neo-adjuvant therapy(NAT).Of the 133 resections,118(89%)were attempted laparoscopically(5%conversion rate).CRM was positive in 9(6.7%)patients;Median lymph node harvest was 12(2-37).Major complications occurred in 8(6%)patients.Median follow-up was 53 mo(0-82).The 90-d mortality was 2(1.5%).Over the followup period,disease related mortality was 11(8.2%)and overall mortality was 39(29.3%).Four(3%)patients had local recurrence and 22(16.5%)patients had distant metastases.CONCLUSION Management of rectal cancers can be optimized with multidisciplinary input to attain acceptable long-term oncological outcomes even when incorporating a laparoscopic approach to rectal cancer resection. | Pawan Kumar Dhruva Rao Sooriyaratchige Pradeep Manjula Peiris Seema Safia Arif Rhodri A Davies Ashraf Gergies Masoud Puthucode Narayanan Haray | 2017 | World Journal of Gastrointestinal Surgery2017，9，6： | 2 |
| 2 | Treatment of Stage IV Breast Cancer with Intact Primary Tumor:A Case for Resection显示文摘 | Gildy B Seema A | 2012 | Curr Breast Cancer Rep2012，4，： | 1 |
| 3 | Microstructural,electrical and reliability aspects of Chromium doped Ni-Mn-Fe-O NTC thermistor materials显示文摘 | Varghese J M Seema A Dayas K R | 2008 | Materials Science and Engineering:B2008，149，1： | 1 |
| 4 | Synthesis of nanosized MgFe2O4 powders by microwave hydrothermal method显示文摘 | VERMA Seema JOY P A KHOLLAM Y B | 2004 | MaterLett2004，58，6： | 1 |
| 5 | Rudimentary horn pregnancy: prerupture diagnosis and management显示文摘 | Seema C Vanita S Neelam A | 2007 | Indian J Med Sci2007，61，1： | 1 |
| 6 | Lymphocyte immunotherapy and its probable mechanism in the maintenance of pregnancy in women with recurrent spontaneous abortion 显示文摘 | Manoj KP Seema T Suraksha A | 2004 | Arch Gynecol Obstet2004，269，3： | 1 |
| 7 | Subcellular localization of the yeast proteome显示文摘 | Anuj K Seema A John A | 2002 | Genes Dev2002，16，： | 1 |
| 8 | Lymphocyte immunotherapy and its probable mechanism in maintenance of pregnancy in women with recurrent spontaneous abortion显示文摘 | Manoj KP Seema T Suraksha A | 2004 | Arch Gynecol Obstet2004，，269： | 1 |
| 9 | 显示文摘 | Seema A Sharma G L | 2002 | Sens Actuators B2002，85，： | 1 |
| 10 | Treatment of Spontaneously Arising Retinoblastoma Tumors in Transgenic Mice with an Attenuated Herpes Simplex Virus Mutant显示文摘 | Curtis R Brandt Pascal D Imesch Nancy L Robinson Nasreen A Syed Seema Untawale Soesiawati R Darjatmoko Richard J Chappell Paul Heinzelman Daniel M Albert | 1997 | Virology1997，，1： | 1 |
| 11 | Synthesis of nanosized MgFe2O4 powders by microwave hydrothermal method 显示文摘 | Seema V Joy P A Khollam Y B | 2004 | Mater Lett2004，58，： | 1 |
| 12 | Preparation and properties of biodegradable starch - clay nanocomposites 显示文摘 | Chung Y L Seema A Luis E | 2010 | Carbohydrate Polymers2010，79，2： | 1 |
| 13 | Microstructural,electrical and reliability aspects of chromium doped Ni-Mn-Fe-O NTC thermistor materials显示文摘 | JUSTIN M V SEEMA A DAYAS K R | 2008 | Mater Sci Eng:B2008，149，1： | 1 |
| 14 | Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study显示文摘 | Karthikeyan K Kumarasamy Mark A Toleman Timothy R Walsh Jay Bagaria Fafhana Butt Ravikumar Balakrishnan Uma Chaudhary Michel Doumith Christian G Giske Seema Irfan Padma Krishnan Anil V Kumar Sunil Maharjan Shazad Mushtaq Tabassum Noorie David L Paterson A | 2010 | The Lancet Infectious Diseases2010，，9： | 1 |
| 15 | microstructural,electrical and reliability aspects of chromium doped Ni-Mn-Fe-O NTC thermistor materials显示文摘 | JUSTIN M Varghese SEEMA A DAYAS K R | 2008 | Mater Sci Eng:B2008，149，1： | 1 |
| 16 | Why do firms volunteer to exceed environmental regulations? Understanding participation in the EPA'S 33/50 program 显示文摘 | Seema A Cason T N | 1996 | Land Economics1996，72，4： | 1 |
| 17 | Synthesis of nanosized MgFe2O4 powders by microwave hydrothermal method显示文摘 | Seema Verma Joy P A Khollam Y B | 2004 | Mater Lett2004，58，： | 1 |
| 18 | Use ofelectrospinning technique for biomedicalapplications显示文摘 | Seema A Joachim H Wendorff | 2008 | Polymer2008，49，： | 1 |
| 19 | Homopolymers and Random Copolymers of 5, 6-Benzo-2-methylene-1, 3-dioxepane and Methyl Methacrylate: Structural Characterization Using 1D and 2D NMR 显示文摘 | Holger W Seema A Andreas G | 2003 | Macromolecules2003，36，： | 1 |
| 20 | Synthesis and Characterization of Copolymers of 5,6-Benzo-2-methylene-1,3-dioxepane and Styrene 显示文摘 | Holger W Seema A | 2003 | Macromolecules2003，36，： | 1 |
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