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| 1 | Ileocecal valve dysfunction in small intestinal bacterial overgrowth: A pilot study显示文摘AIM: To explore whether patients with a defective ileocecal valve (ICV)/cecal distension reflex have small intestinal bacterial overgrowth. METHODS: Using a colonoscope, under conscious sedation, the ICV was intubated and the colonoscope was placed within the terminal ileum (TI). A manometry catheter with 4 pressure channels, spaced 1 cm apart, was passed through the biopsy channel of the colonoscope into the TI. The colonoscope was slowly withdrawn from the TI while the manometry catheter was advanced. The catheter was placed across the ICV so that at least one pressure port was within the TI, ICV and the cecum respectively. Pressures were continuously measured during air insufflation into the cecum, under direct endoscopic visualization, in 19 volunteers. Air was insufflated to a maximum of 40 mmHg to prevent barotrauma. All subjects underwent lactulose breath testing one month after the colonoscopy. The results of the breath tests were compared with the results of the pressures within the ICV during air insufflation. RESULTS: Nineteen subjects underwent colonoscopy with measurements of the ICV pressures after intubation of the ICV with a colonoscope. Initial baseline readings showed no statistical difference in the pressures of the TI and ICV, between subjects with positive lactulose breath tests and normal lactulose breath tests. The average peak ICV pressure during air insufflation into the cecum in subjects with normal lactu-lose breath tests was significantly higher than cecal pressures during air insufflation (49.33 ± 7.99 mmHg vs 16.40 ± 2.14 mmHg, P = 0.0011). The average percentage difference of the area under the pressure curve of the ICV from the cecum during air insufflations in subjects with normal lactulose breath tests was significantly higher (280.72% ± 43.29% vs 100% ± 0%, P = 0.0006). The average peak ICV pressure during air insufflation into the cecum in subjects with positive lactulose breath tests was not significantly different than cecal pressures during air insufflation 21.23 ± 3.52 mmHg vs 16.10 ± 3.39 mmHg. The average percentage difference of the area under the pressure curve of the ICV from the cecum during air insufflation was not significantly different 101.08% ± 7.96% vs 100% ± 0%. The total symptom score for subjects with normal lactulose breath tests and subjects with positive lactu-lose breath tests was not statistically different (13.30 ± 4.09 vs 24.14 ± 6.58). The ICV peak pressures during air insufflations were significantly higher in subjects with normal lactulose breath tests than in subjects with positive lactulose breath tests (P = 0.005). The average percent difference of the area under the pressure curve in the ICV from cecum was significantly higher in subjects with normal lactulose breath tests than in subjects with positive lactulose breath tests (P = 0.0012). Individuals with positive lactulose breath tests demonstrated symptom scores which were significantly higher for the following symptoms: not able to finish normal sized meal, feeling excessively full after meals, loss of appetite and bloating. CONCLUSION: Compared to normal, subjects with a positive lactulose breath test have a defective ICV cecal distension reflex. These subjects also more commonly have higher symptom scores. | Larry S Miller Anil K Vegesna Aiswerya Madanam Sampath Shital Prabhu Sesha Krishna Kotapati Kian Makipour | 2012 | World Journal of Gastroenterology2012，18，46： | 3 |
| 2 | Textural Analysis of IRS-ID Panchromatic Data for Land Cover Classification 显示文摘 | Narasimha R P V Sesha S M V R Sreenivas K | 2002 | International Journal of Remote Sensing2002，23，17： | 1 |
| 3 | Textural Analysis of IRS - 1 D Panchromatic Data for Land Cover Classification 显示文摘 | Narasimha R P V Sesha S M V R Sreenivas K | 2002 | International Journal of Remote Sensing2002，23，17： | 1 |
| 4 | 显示文摘 | Sesha S Srinivasan Hendrik W Brinks Bjorn C Hauback | 2004 | J Alloys Compd2004，377，： | 1 |
| 5 | Spatiotemporal analysis of meteorological drought variability in the Indian region using standardized precipitation index显示文摘 | Naresh Kumar M Murthy C S Sesha Sai M V R | 2012 | Meteorological Applications2012，19，2： | 1 |
| 6 | Textural Analysis of IRS-1D Panchromatic Data for Land Cover Classiflcation 显示文摘 | NARASIMHA R P V SESHA S M V R | 2002 | International Journal of Remote Sensing2002，23，17： | 1 |
| 7 | The estimation ofsurface temperature over an agricultural area in the state ofHaryana and Panjab,India, and its relationship with the NormalizedDifference Vegetation Index (NDVI), using NOAA-AVHRR data显示文摘 | Gupta R K Prasad S Sesha Sai M V R | 1997 | International Journal of Remote Sensing1997，18，： | 1 |
| 8 | Nano-Ni Doped Li-Mn- B-H System as a New Hydrogen Storage Candidate 显示文摘 | Pabitra C Sesha S Venkat R B | 2009 | Int J Hydrogen Energy2009，34，15： | 1 |
| 9 | Long Term Cycling Behavior of Titanium Doped NaAlH4 Prepared through Solvent Mediated Milling of NaH and Al with Titanium Dopant Precursors显示文摘 | SESHA S SRINIVASAN HENDRIK W Brinks Bjorn C Hauback | 2004 | Alloys Compd2004，377，12： | 1 |
| 10 | Surface soil moisture changes during 2007 summer monsoon season derived from AMSR-E Land 3 product显示文摘 | Chandrasekar K Sesha Sai M V R Dwivedi R S | 2008 | Current Science2008，95，12： | 1 |
| 11 | 显示文摘 | Sun Dalin Srinivasan Sesha S | 2004 | J Alloys Comp2004，373，： | 1 |
| 12 | Effects of catalysts doping on the thermal decomposition behavior of Zn(BH4)2显示文摘 | SESHA S DIEGO E YOGI G | 2008 | Int J Hydrogen Energy2008，33，9： | 1 |
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