|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Effect of proteins,polysaccharides,and particle sizes on sludge dewaterability显示文摘Four batch experiments of hydrolysis and acidification were carried out to investigate the distributions of proteins(PN) and polysaccharides(PS) in the sludge,the PN/PS ratio,the particle sizes,and their relationship with sludge dewaterability(as determined by capillary suction time,CST) . The sludge flocs were stratified through centrifugation-and ultrasound-based method into four fractions:(1) slime,(2) loosely bound extracellular polymeric substances(LB-EPS) ,(3) tightly bound EPS(TB-EPS) ,and(4) pellet. The results showed that PN was mainly partitioned in the pellet(80.7%) and TB-EPS(9.6%) fractions,while PS distributed evenly in the four fractions. During hydrolysis and acidification,PN was transferred from the pellet and TB-EPS fractions to the slime fraction,but PS had no significant transfer trends. The mean particle sizes of the sludge flocs decreased with hydrolysis and acidification. The pH had a more significant influence on the dewaterability of sludge flocs than temperature. Sludge dewaterability during hydrolysis and acidification processes greatly deteriorated from 9.7 s at raw sludge to 340-450 s under alkaline conditions. However,it was just slightly increased under acidic conditions. Further investigation suggested that CST was affected by soluble PN,soluble PN/PS,and particle sizes of sludge flocs,but was affected slightly by total PN,PS,or PN/PS in the whole sludge flocs and other fractions(except slime) . | SHAO Liming,HE Peipei,YU Guanghui,HE Pinjing State Key Laboratory of Pollution Control and Resources Reuse,Key Laboratory of Yangtze River Water Environment,College of Environmental Science and Engineering,Tongji University,Shanghai 200092,China | 2009 | Journal of Environmental Sciences2009，21，1： | 37 |
| 2 | Effects of ultrasonic pretreatment on sludge dewaterability and extracellular polymeric substances distribution in mesophilic anaerobic digestion显示文摘Effect of ultrasonic pretreatment on sludge dewaterability was determined and the fate of extracellular polymeric substances (EPS) matrix in mesophilic anaerobic digestion after ultrasonic pretreatment was studied. Characteristics of proteins (PN), polysaccharides (PS), excitation-emission matrix (EEM) fluorescence spectroscopy and molecular weight (MW) distribution of dissolved organic matters (DOM) in different EPS fractions were evaluated. The results showed that after ultrasonic pretreatment, the normalized capillary suction time (CST) decreased from 44.4 to 11.1 (sec·L)/g total suspended solids (TSS) during anaerobic digestion, indicating that sludge dewaterability was greatly improved. The normalized CST was significantly correlated with PN concentration (R2 = 0.92, p < 0.01) and the PN/PS ratio (R2 = 0.84, p < 0.01) in the loosely bound EPS (LB-EPS) fraction. Meanwhile, the average MW of DOM in the LB- EPS and tightly bound EPS (TB-EPS) fractions also had a good correlation with the normalized CST (R2 > 0.66, p < 0.01). According to EEM fluorescence spectroscopy, tryptophan-like substances intensities in the slime, LB-EPS and TB-EPS fractions were correlated with the normalized CST. The organic matters in the EPS matrix played an important role in influencing sludge dewaterability. | Liming Shao Guanzhao Wang Huacheng Xu Guanghui Yu Pinjing He | 2010 | Journal of Environmental Sciences2010，22，3： | 29 |
| 3 | Model and Algorithm for the Optimal Controlled Partitioning of Power Systems显示文摘解列是电力系统在故障时结构完整性得不到保证的情况下分裂为2个或多个孤立稳定运行子系统的过程或操作。及时恰当的主动解列操作将能有效地避免因保护连锁动作使得电力系统被动解列而崩溃所造成的巨额经济损失。结合图论中的相关概念和输电网最优解列的物理过程,建立电力系统最优主动解列断面选择问题的完整数学模型,并基于含连通图约束的背包问题(connected graph constrained knapsack problem,CGKP)及其求解算法提出“搜索+调整”的2阶段求解方法。为降低问题的复杂性,将完整数学模型分解成图的最优平衡分割问题和基于优化潮流的调节问题,并分2个阶段分别求解。其中,图的最优平衡分割问题又被分解成多个CGKP,利用基于含CGKP的图分割方法进行求解。所提出的主动解列策略具有较强理论基础,计算复杂度低,算例的计算结果证明了该模型及算法的正确性和有效性。 | LIN Jikeng LI Shengwen WU Peng WANG Xudong SHAO Guanghui XU Xingwei MA Xin | 2012 | 中国电机工程学报2012，32，13： | 15 |
| 4 | Effect of ultrasonic pretreatment on anaerobic digestion and its sludge dewaterability显示文摘To investigate the effect of ultrasonic pretreatment on anaerobic digestion and sludge dewaterability and further to probe into the influencing factors on sludge dewaterability,sludge flocs were stratified into four fractions: (1) slime;(2) loosely bound extracellular polymeric substances (LB-EPS);(3) tightly bound EPS (TB-EPS);and (4) EPS-free pellets.The results showed that ultrasonic pretreatment increased the anaerobic digestion efficiency by 7%–8%.Anaerobic digestion without ultrasonic pretreatment deteriorated the sludge dewaterability,with the capillary suction time (CST) increased from 1.42 to 47.3 (sec·L)/g-TSS.The application of ultrasonic pretreatment firstly deteriorated the sludge dewaterability (normalized CST increased to 44.4 (sec·L)/g-TSS),while subsequent anaerobic digestion offset this effect and ultimately decreased the normalized CST to 23.2 (sec·L)/g-TSS.The dewaterability of unsonicated sludge correlated with protein (p = 0.003) and polysaccharide (p = 0.004) concentrations in the slime fraction,while that of sonicated sludge correlated with protein concentrations in the slime and LB-EPS fractions (p < 0.05).Fluorescent excitationemission matrix analysis showed that the fluorescence matters in the LB-EPS fraction significantly correlated with sludge dewaterability during anarobic digestion. | Huacheng Xu Pinjing He Guanghui Yu Liming Shao | 2011 | Journal of Environmental Sciences2011，23，9： | 13 |
| 5 | Enzyme extraction by ultrasound from sludge flocs显示文摘Enzymes play essential roles in the biological processes of sludge treatment.In this article,the ultrasound method to extract enzymes from sludge flocs was presented.Results showed that using ultrasound method at 20 kHz could extract more types of enzymes than that at 40 kHz and ethylenediamine tetraacetic acid(EDTA) methods.The optimum parameters of ultrasound extraction at 20 kHz were duration of 10 min and intensity of 552 W/g TSS.Under the optimum condition,ultrasound could break the cells and extract both the extracellular and a small part of intercellular enzymes.Ultrasound intensity was apparently more susceptive to enzyme extraction than duration,suggesting that the control of intensity during ultrasound extraction was more important than that of duration.The Pearson correlation analysis between enzyme activities and cation contents revealed that the different types of enzymes had distinct cation binding characteristics. | YU Guanghui,HE Pinjing,SHAO Liming,ZHU Yishu State Key Laboratory of Pollution Control and Resource Reuse,Key Laboratory of Yangtze River Water Environment,College of Environmental Science and Engineering,Tongji University,Shanghai 200092,China. | 2009 | Journal of Environmental Sciences2009，21，2： | 8 |
| 6 | Multi-level multi-area hybrid automatic voltage control system and its trial operation in Northeast China Grid显示文摘In order to coordinate automatic voltage control(AVC)systems of a large interconnected system,a multi-level multi-area hybrid automatic voltage control(MLMA-HAVC)system was constructed.This system began its trial operation in the Northeast China Grid in January 2010,and for the first time in China and abroad it realized automatic close-loop control of multi-area and multi-level interconnected power grid and multi-objective self-approaching optimization in aspects of security,high quality and economic operation.This system has three breakthroughs in theory and engineering application:1)Established the MLMA-HAVC theory to solve multi-objective optimization of large-scale system;2)proposed reactive power/voltage coordination control method to inhibit or further eliminate regional oscillations;3)presented advanced state estimation algorithm to guarantee acquisition of high reliability data.This paper summarizes the basic principle of MLMA-HAVC,and reports engineering realization of MLMA-HAVC system in the Northeast China Grid. | ZHANG XueMin MEI ShengWei SU XinYi WANG Gang JIA Wei SHAO GuangHui XU XingWei | 2011 | Science China(Technological Sciences)2011，54，9： | 6 |
| 7 | Research on practical power system stability analysis algorithm based on modified SVM显示文摘Stable and safe operation of power grids is an important guarantee for economy development.Support Vector Machine(SVM)based stability analysis method is a significant method started in the last century.However,the SVM method has several drawbacks,e.g.low accuracy around the hyperplane and heavy computational burden when dealing with large amount of data.To tackle the above problems of the SVM model,the algorithm proposed in this paper is optimized from three aspects.Firstly,the gray area of the SVM model is judged by the probability output and the corresponding samples are processed.Therefore the clustering of the samples in the gray area is improved.The problem of low accuracy in the training of the SVM model in the gray area is improved,while the size of the sample is reduced and the efficiency is improved.Finally,by adjusting the model of the penalty factor in the SVM model after the clustering of the samples,the number of samples with unstable states being misjudged as stable is reduced.Test results on the IEEE 118-bus test system verify the proposed method. | Kaiyuan Hou Guanghui Shao Haiming Wang Le Zheng Qiang Zhang Shuang Wu Wei Hu | 2018 | Protection and Control of Modern Power Systems2018，3，1： | 5 |
| 8 | Anti-windup design for the controllers of integrating processes with long delay显示文摘For several superior controllers of the first-order integrating processes with long delay, the windup problems are analyzed in detail when the control signal saturates. The results show that these controllers have similar characteristics about the process input limitation. And then, a simple and effective anti-windup scheme, without an additional parameter, is designed for these controllers. Simulations run with three main controllers, and the results illustrate that the proposed method may achieve good performance under the nominal and model uncertainty cases. | Zhang Guanghui Shao Huihe | 2007 | Journal of Systems Engineering and Electronics2007，18，2： | 2 |
| 9 | Robust tuning method for modified smith predictor显示文摘A robust tuning method for strm’s two-degree of Freedom Modified Smith Predictor (MSP) is proposed, and it can achieve the fast setpoint and load disturbance responses independently. The tuning rules may meet the requirements within a certain delay margin according to the robustness theory. The simulation results illustrate that the tuning method is efficient compared with other controllers. Finally, the MSP controller is applied to the 15L batch fermentation system for controlling the temperature in bioreactor, and the experiment results further verify that the robust tuning rules may achieve good performance. | Zhang Guanghui Qian Feng Shao Huihe | 2007 | Journal of Systems Engineering and Electronics2007，18，1： | 2 |
| 10 | Characteris tics of extracellular polymeric substances (EPS) fractions from excess sludges and their effects on bioflocculability显示文摘 | YU Guanghui HE Pinjing SHAO Liming | 2009 | Bioresource Technology2009，100，13： | 1 |
| 11 | Research and prac- tice of mobile navigation system显示文摘 | SHAO Zhiju CUI Guanghui | 2008 | Graduate University of Chinese Academy of Sciences2008，，： | 1 |
| 12 | Stratification structure of sludge flocs with implications to dewaterability显示文摘 | YU Guanghui HE Pingjing SHAO Liming | 2008 | Environmental Science & Technology2008，42，21： | 1 |
| 13 | Enzyme activities in activated sludge flocs显示文摘 | YU Guanghui HE Pinjing SHAO Liming | 2007 | Applied Microbiology and Biotechnology2007，77，3： | 1 |
| 14 | Characteristics of extracellular polymeric substances (EPS) fractions from excess sludges and their effects on bioflocculability 显示文摘 | YU Guanghui HE Pinjing SHAO Liming | 2009 | Bioresource Technology2009，100，13： | 1 |
| 15 | A targeted covalent inhibitor of p97 with proteome-wide selectivity显示文摘A resurging interest in targeted covalent inhibitors(TCIs)focus on compounds capable of irreversibly reacting with nucleophilic amino acids in a druggable target.p97 is an emerging protein target for cancer therapy,viral infections and neurodegenerative diseases.Extensive efforts were devoted to the development of p97 inhibitors.The most promising inhibitor of p97 was in phase 1 clinical trials,but failed due to the off-target-induced toxicity,suggesting the selective inhibitors of p97 are highly needed.We report herein a new type of TCIs(i.e.,FL-18)that showed proteome-wide selectivity towards p97.Equipped with a Michael acceptor and a basic imidazole,FL-18 showed potent inhibition towards U87 MG tumor cells,and in proteome-wide profiling,selectively modified endogenous p97 as confirmed by in situ fluorescence scanning,label-free quantitative proteomics and functional validations.FL-18 selectively modified cysteine residues located within the D2 ATP site of p97.This covalent labeling of cysteine residue in p97 was verified by LC-MS/MS-based site-mapping and site-directed mutagenesis.Further structure-activity relationship(SAR)studies with FL-18 analogs were established.Collectively,FL-18 is the first known small-molecule TCI capable of covalent engagement of p97 with proteome-wide selectivity,thus providing a promising scaffold for cancer therapy. | Zi Ye Ke Wang Lianguo Chen Xiaofeng Jin Hao Chen Guanghui Tang Shao Q.Yao Zhiqiang Feng Chong-Jing Zhang | 2022 | Acta Pharmaceutica Sinica B2022，12，2： | 1 |
| 16 | Enzyme ac- tivities in activated sludge flocs显示文摘 | YU Guanghui HE Pinjing SHAO Liming | 2007 | Applied Microbiology and Biotechnology2007，77，3： | 1 |
| 17 | Characteristics of extra- cellular polymeric substances (EPS) fractions from excess sludges and their effects on bioflocculability 显示文摘 | Yu Guanghui He Pinjing Shao Liming | 2009 | Bioresource Technology2009，100，13： | 1 |
| 18 | Novel insights into sludge dewaterability by fluorescence excitation-emission matrix combined with parallel factor analysis 显示文摘 | YU Guanghui HE Pinjing SHAO Liming | 2010 | Water Res2010，44，3： | 1 |
| 19 | Protein corona mediated liposomal drug delivery for bacterial infection management显示文摘Liposomes have been widely investigated as a class of promising antibiotic delivery systems for the treatment of life-threatening bacterial infections.However,the inevitable formation of protein corona on the liposomal surface can heavily impact in vivo performance.A better understanding of the effects of protein corona on liposomal behavior can significantly improve antibacterial liposomal drug development.Here,the critical role of protein corona in mediating liposome-bacteria interactions was elucidated.Adsorption of negatively charged protein on cationic liposome weakened electrostatic attractionenhanced liposomal binding to the bacteria.Cumulative complement deposition on anionic liposome composed of phosphatidylglycerol(DSPG s Lip)contributed to a superior binding affinity of DSPG s Lip to planktonic bacteria and biofilms,which was exploited to enhance bacteria-targeted drug delivery.In both S.aureus-related osteomyelitis and pneumonia mice models,DSPG s Lip was demonstrated as a promising antibiotic nanocarrier for managing MRSA infection,indicating the benefits of lipid composition-based protein corona modulation in liposomal antibiotic delivery for bacterial infection treatment. | Qianwen Shao Tianhao Ding Feng Pan Guanghui Li Shun Shen Jun Qian Changyou Zhan Xiaoli Wei | 2022 | Asian Journal of Pharmaceutical Sciences2022，17，6： | 0 |
| 20 | Anti-aging activity and their mechanisms of natural food-derived peptides:current advancements显示文摘Recently,there has been a growing focus on researching ways to delay aging and protect against age-related illnesses.Small molecular exogenous peptides,sourced from dietary elements like animals,plants,and microorganisms,have demonstrated considerable potential in exerting anti-aging effects.Notably,natural food-derived peptides have exhibited enhanced stability,safety,absorption efficiency,and heightened biological activity.These attributes position them with a greater potential for mitigating aging-related disorders compared to alternative anti-aging drugs or phytochemicals.This review summarizes the origins,structural attributes,and isolation methods of natural foodderived peptides with anti-aging properties.It also explores how these external peptides improve aging-related conditions such as neurodegenerative diseases,skin aging,and metabolic disorders.The underlying mechanisms dictating their impact on well-conserved signaling pathways—encompassing oxidative stress,inflammation,apoptosis,and collagen synthesis—are meticulously elucidated.This paper engages in an insightful exploration of the key challenges and pivotal trajectories,grounded in ongoing research endeavors.As a result,this review is poised to offer authoritative scientific guidance and invaluable support for the practical implementation of natural food-derived peptides in the realm of anti-aging applications within the food,pharmaceutical,and cosmetic industries. | Jialong Li Jiaojiao Wang Ning Zhang Ying Li Zizhe Cai Guanghui Li Zhongbo Liu Zhiping Liu Yong Wang Xin Shao Jing Chen | 2023 | Food Innovation and Advances2023，2，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员