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| 1 | Adenosquamous carcinoma of the pancreas: Molecular characterization of 23 patients along with a literature review显示文摘Adenosquamous carcinoma of the pancreas(ASCP)is a rare entity. Like adenocarcinoma of the pancreas,overall survival is poor. Characteristics of ASCP include central tumor necrosis, along with osteoclasts and hypercalcemia. Various theories exist as to why this histological subtype exists, as normal pancreas tissue has no benign squamous epithelium. Due to the rarity of this disease, limited molecular analysis has been performed, and those reports indicate unique molecular features of ASCP. In this paper, we characterize 23 patients diagnosed with ASCP through molecular profiling using immunohistochemistry staining, fluorescent in situ hybridization, chromogenic in situ hybridization, and gene sequencing, Additionally, we provide a comprehensive literature review of what is known to date of ASCP.Molecular characterization revealed overexpression in MRP1(80%), MGMT(79%), TOP2A(75), RRM1(42%),TOPO1(42%), PTEN(45%), CMET(40%), and C-KIT(10%) among others. One hundred percent of samples tested were positive for KRAS mutations. This analysis shows heretofore unsuspected leads to be considered for treatments of this rare type of exocrine pancreas cancer. Molecular profiling may be appropriate to provide maximum information regarding the patient's tumor. Further work should be pursued to better characterize this disease. | Erkut Borazanci Sherri Z Millis Ron Korn Haiyong Han Clifford J Whatcott Zoran Gatalica Michael T Barrett Derek Cridebring Daniel D Von Hoff | 2015 | World Journal of Gastrointestinal Oncology2015,7,9: | 6 |
| 2 | Gynecologic oncologists involvement on ovarian cancer standard of care receipt and survival显示文摘AIM:To examine the influence of gynecologic oncolo-gists(GO) in the United States on surgical/chemotherapeutic standard of care(SOC), and how this translates into improved survival among women with ovarian cancer(OC).METHODS: Surveillance, Epidemiology, and End Result(SEER)-Medicare data were used to identify 11688 OC patients(1992-2006). Only Medicare recipients with an initial surgical procedure code(n = 6714) were included. Physician specialty was identified by linking SEER-Medicare to the American Medical Association Masterfile. SOC was defined by a panel of GOs. Multivariate logistic regression was used to determine predictors of receiving surgical/chemotherapeutic SOCand proportional hazards modeling to estimate the effect of SOC treatment and physician specialty on survival. RESULTS: About 34% received surgery from a GO and 25% received the overall SOC. One-third of women had a GO involved sometime during their care. Women receiving surgery from a GO vs non-GO had 2.35 times the odds of receiving the surgical SOC and 1.25 times the odds of receiving chemotherapeutic SOC(P < 0.01). Risk of mortality was greater among women not receiving surgical SOC compared to those who did [hazard ratio = 1.22(95%CI: 1.12-1.33), P < 0.01], and also was higher among women seen by non-GOs vs GOs(for surgical treatment) after adjusting for covariates. Median survival time was 14 mo longer for women receiving combined SOC. CONCLUSION: A survival advantage associated with receiving surgical SOC and overall treatment by a GO is supported. Persistent survival differences, particularly among those not receiving the SOC, require further investigation. | Sun Hee Rim Shawn Hirsch Cheryll C Thomas Wendy R Brewster Darryl Cooney Trevor D Thompson Sherri L Stewart | 2016 | World Journal of Obstetrics and Gynecology2016,5,2: | 3 |
| 3 | The diagnosis and incidence of allergic fungal sinusitis显示文摘 | PONIKAU J U SHERRIS D A KERN E B | 1999 | Mayo Clin Proc1999,74,: | 1 |
| 4 | Seasonal and spatial patterns of heterotrophic bacterial production, respiration, and biomass in the subarctic NE Pacific显示文摘 | Sherry N D Boyd P W Sugimoto K | 1999 | Deep - Sea Research H1999,46,: | 1 |
| 5 | Know ledge discovery by inspection 显示文摘 | Mc Sherry D | 1997 | Decision Support Systems1997,21,: | 1 |
| 6 | Feature of air- way remodeling and eosinophilic inflammation inehronic rhinosinusitis:is the hospitathology similar to asthma显示文摘 | Ponikau I U Sherris D A Kephart G M | 2003 | J Allergy Clin Immunol2003,112,5: | 1 |
| 7 | Potential therapeutic roles for inhibition of the PI3K/Akt/mTOR pathway in the pathophysiology of di- abetic retinopathy 显示文摘 | Jacot JL Sherris D | 2011 | J Ophthalmol2011,2011,58: | 1 |
| 8 | Chemical exchange saturation transfer contrast agents for magnetic resonance imaging 显示文摘 | Sherry A D Woods M | 2008 | Annu Rev Biomed Eng2008,10,: | 1 |
| 9 | Prevention and Intervention Srategies to Alleviate Preoperative Anxiety in Children A Critial Review显示文摘 | Kristi D Wright Sherry H Stewart G | 2007 | Behavior Modification2007,31,1: | 1 |
| 10 | Sudden cardiac death in patients with rheumatoid arthritis显示文摘An increased cardiovascular morbidity and mortality, including the risk of sudden cardiac death(SCD), has been shown in patients with rheumatoid arthritis(RA). Abnormalities in autonomic markers such as heart rate variability and ventricular repolarization parameters, such as QTc interval and QT dispersion, have been associated with sudden death in patients with RA. The interplay between these parameters and inflammation that is known to exist with RA is of growing interest. In this article, we review the prevalence and predictors of SCD in patients with RA and describe the potential underlying mechanisms, which may contribute to this. We also review the impact of biologic agents on arrhythmic risk as well as cardiovascular morbidity and mortality. | Sherry Masoud Phang Boon Lim George D Kitas Vasileios Panoulas | 2017 | World Journal of Cardiology2017,9,7: | 1 |
| 11 | Residual Stress Driven Creep Cracking in Type 316 Stainless Steel显示文摘 | TURSKI M SHERRY A H BOUCHARD P J et d | 2004 | Journal of neutron research2004,12,1: | 1 |
| 12 | Fracture complicating the bone marrow edema syndrome显示文摘 | SHERRY A GUARDIANO D O JAMES K | 2004 | J Clin Rheumatol2004,10,5: | 1 |
| 13 | Keloid disease can be inhibited by antagonizing excessive mTOR signaling with a novel dual TORCI/2 inhibitor显示文摘 | Syed F Sherris D Pans R | 2012 | Am JPathol2012,181,5: | 1 |
| 14 | Evaluating the com-parative managerial efficiency of leading third party logis-tics providers in North America显示文摘 | MIN Hokey SHERRIE L D S-J Joo | 2013 | Benchmarking2013,20,1: | 1 |
| 15 | Features of airway remodeling and eosinophilic inflammation in chronic rhinosinusitis:Is the histophathology similar to asthma显示文摘 | Ponikau J U Sherris D A Kephart G M | | 0,,05: | 1 |
| 16 | Royalties, Evolving Patent Rights, and the Value of Innovation显示文摘 | Sherry E F Teece D J | 2013 | Research Policy2013,,5: | 1 |
| 17 | Initial and Extended Use of Femoral Versus Nonfemoral Double-Lumen Vascular Catheters and Catheter Related Infection During Continuous Renal Repleement Therapy 显示文摘 | Chua HR Schnejder AG Sherry NL et d | 2014 | Am J Kidney Dis2014,64,6: | 1 |
| 18 | Features of airway remodeling and eosinophilic inflammation in chronic rhinosinusitis:is the histopathology similar to asthma?显示文摘 | SHERRIS D A KEPHART G M | 2003 | J Allergy Clin Immunol2003,112,: | 1 |
| 19 | Murine macrophage activation by staphylococcal exotoxins 显示文摘 | SHERRY D JOHN J STEPHEN K C | 1991 | Infection and Immunity1991,59,11: | 1 |
| 20 | Human acellular dermal matrix grafts for rhinoplasty显示文摘 | Sherris D A Oriel B S | 2011 | Aesthet Surg J2011,31,7: | 1 |