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1Colonoscopic yield of colorectal neoplasia in daily clinical practice显示文摘AIM:To assess the prevalence and location of ad-vanced neoplasia in patients undergoing colonoscopy,and to compare the yield per indication.METHODS:In a multicenter colonoscopy survey (n = 18 hospitals) in the Amsterdam area (Northern Holland),data of all colonoscopies performed during a three month period in 2005 were analyzed. The location and the histological features of all colonic neoplasia were recorded. The prevalence and the distribution ofadvanced colorectal neoplasia and differences in yield between indication clusters were evaluated. Advanced neoplasm was defi ned as adenoma > 10 mm in size,with > 25% villous features or with high-grade dyspla-sia or cancer.RESULTS:A total of 4623 eligible patients underwent a total colonoscopy. The prevalence of advanced neo-plasia was 13%,with 281 (6%) adenocarcinomas and 342 (7%) advanced adenomas. Sixty-seven percent and 33% of advanced neoplasia were located in the distal and proximal colon,respectively. Of all patients with right-sided advanced neoplasia (n = 228),51% had a normal distal colon,whereas 27% had a syn-chronous distal adenoma. Ten percent of all colono-scopies were performed in asymptomatic patients,7% of whom had advanced neoplasia. In the respective procedure indication clusters,the prevalence of right-sided advanced neoplasia ranged from 11%-57%. CONCLUSION:One out of every 7-8 colonoscopies yielded an advanced colorectal neoplasm. Colonoscopy is warranted for the evaluation of both symptomatic and asymptomatic patients.Jochim S Terhaar sive Droste Mike E Craanen Rene WM van der Hulst Joep F Bartelsman Dick P Bezemer Kim R Cappendijk Gerrit A Meijer Linde M Morsink Pleun Snel Hans ARE Tuynman Roy LJ van Wanrooy Eric IC Wesdorp Chris JJ Mulder 2009World Journal of Gastroenterology2009,15,9:6
2Comparative assessment of largescale data sets of protein-protein interactions显示文摘von Mering C Krause R Snel B 2002Nature2002,417,:1
3Compara- tive assessment of large-scale data sets of protein-protein interactions 显示文摘VON MERING C KRAUSE R SNEL B 2002Nature2002,417,6887:1
4High pressure can reduce the antigenicity of bovine whey protein hydrolysates 显示文摘Penas E Snel H Floris R 2006International Dairy Journal2006,16,:1
5Comparative Assessment of Large-scale Data Sets of Protein-protein Interaetlons显示文摘Von Meting C Krause R Snel B 2002Nature2002,417,:1
6Catalytic oligomerization of ethene over nickel-exchanged amorphous silica-aluminas;effect of the acid strength of the support显示文摘 Snel R Korf C J 1987Appl Catal1987,29,2:1
7On-line chromatographic analysis of light Fischer-Tropsch synthesis products 显示文摘SNEL R 1986Chromatographia1986,21,5:1
8On-line gas chromatographic analysis of light Fischer-Tropsch synthesis products 显示文摘SNEL R 1986Chroma tographia1986,21,5:1
9Comparative assessment of large-scale data sets of protein-protein interactions 显示文摘Meting C Krause R Snel B 2002Nature2002,417,6887:1
10The nature of hydrocarbon synthesis by means of hydrogenation of carbon monoxide on iron-based catalysts: Part Ⅰ hydrogenation-strength distribution of surface sites显示文摘SNEL R 1989J Mol Catal1989,53,1:1
11Comparative assessment of large-scale data sets of protein-protein interactions显示文摘von Mering C Krause R Snel B 2002Nature2002,417,6887:1
12Comparative Assessment of Large-scale Data Sets of Protein-protein Interactions 显示文摘von Mering C Krause R Snel B 2002Nature2002,417,6887:1
13The relation between Laser - In- duced chlorophyll fluorescence and photosynthesis 显示文摘Rosema R Snel J F H Zahn H 1998Remote Sensing of Environment1998,65,:1
14On-line gas chromatographic analysis of light Fischer-Tropsch synthesis products显示文摘Snel R 1986Chromatographia1986,21,5:1
15Inhibition of photosystem H (PS H ) electron transport as a convenient endpoint to assess stress of the herbicide linuron on freshwater plants 显示文摘Snel JFH Vos JH Gylstra R 1998Aquatic Ecol1998,32,:1
16Enhanced antigen-specific delayed-type hypersensitivity and immunoglobulin G2b responses after oral administration of viable Lactobacillus casei YIT9029 in Wistar and Brown Norway rats显示文摘De Waard R GARSSEN J SNEL J 2001Clin Diagn Lab Immunol2001,8,:1
17Comparative assessmentof large-scale data sets of protein-protein interactions 显示文摘Von Mering C K rause R Snel B 2002Na- ture2002,417,:1
18Comparative assessment of large-scale data sets of protein-protein interactions 显示文摘von Mering C Krause R Snel B 2002Nature2002,417,6887:1
19Comparative assessment of large-scale datasets of protein-protein interactions 显示文摘yon MERING C KRAUSE R SNEL B 2002Nature2002,417,:1
20Comparative assessment of large-scale data sets of protein-protein interactions显示文摘MERING C V KRAUSE R SNEL B 2002Nature2002,417,:1
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