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1Interplay between nitric oxide and VIP in CCK-8-induced phasic contractile activity in the rabbit sphincter of Oddi显示文摘AIM: The sphincter of Oddi (SO) plays an important role in delivery of bile into the duodenum. To establish whether vasoactive intestinal polypeptide (VIP) and nitric oxide (NO) were involved in phasic contractile activity of the rabbit SO stimulated by cholecystokinin-octapeptide (CCK-8).METHODS: Isolated SO muscle rings were cleaned of fat and mounted horizontally on two small L-shaped hooksone of which was connected to a force transducer for the measurement of isometric tension. The experiments were carried out in a thermostatically controlled (37±0.2℃)organ bath (5 mL) containing Krebs solution. The organ fluid was gassed with 95% O2 and 50 mL/L CO2 to keep the pH at 7.40±0.05. Contractile responses to CCK-8 (1μmol/L) were evaluated in the presence and absence of N^G-nitro-L-arginine (LNNA), an inhibitor of NO synthase (100μmol/L), and (p-chloro-D-Phe^6-Leu^17)-VIP (VIPa,30μmol/L), a VIP receptor antagonist.RESULTS: CCK-8 stimulated the phasic activity of the SO.NO synthase inhibition increased the frequency and amplitude of contractions with a slight increase in developed tension.Pre-incubation with VIPa also attenuated this CCK-8 effect.The combined application of LNNA and VIPa abolished the phasic activity of the muscle rings with a marked increase in tension in response to CCK-8.CONCLUSION: VIP and NO together contribute to an increase in phasic activity of SO.Attila Pálv(o|¨)lgyi Réka Sári József Németh Annamária Szabolcs István Nagy Péter Hegyi János Lonovics Zoltán Szilvássy 2005World Journal of Gastroenterology2005,11,21:11
2Alkaline high power batteries in a bipolar stack design 显示文摘OHMS D KOHLHASE M BENCZUR- URMO SSY G 2001Journal of Power Sources2001,96,:2
3High performance nickel-metal hydride battery in bipolar stack design显示文摘OHMS D KOHLHASE M BENCZUR- URM O SSY G 2002Journal of Power Sources2002,105,:2
4Capsaicin-sensitive local sensory innervation is involved in pacing-induced preconditioning in rat hearts: role of nitric oxide and CGRP?显示文摘P. Ferdinandy Tamás Csont Csaba Csonka Marianna T?r?k Mária Dux József Németh László I. Horváth László Dux Zoltán Szilvássy Gábor Jancsó 1997Naunyn - Schmiedeberg’s Archives of Pharmacology1997,,3:1
5Lowering the Outdoor Temperature in High-rise High-Density Residential Developments of Coastal Hong Kong:the Vegetation Influence显示文摘Giridharan R Lau SSY Ganesan S 0,,10:1
6Serodiagnosis of penicillium marneffei infection显示文摘Yuen KY Wong SSY Tsang DNC 1994Lancet1994,344,8920:1
7Blood flow volume quantification of cerebral ischemia:comparison of three noninvasive imaging techniques of carotid and vertebral arteries显示文摘Ho SSY Chan YL Yeung DKW 2002AJR Am J Roentgenol2002,178,:1
8Fast FISH : technique for ultrarapid fluorescence in situ hybridization on uncultured amniocytes yielding results within 2 h of amniocentesis 显示文摘Choolani M Ho SSY Razvi K 2007Molecular Human Reproduction2007,13,6:1
9One-dimensional modeling of dam break flow over movable beds显示文摘Wu WM Wang SSY 2007J Hydraul Eng2007,133,1:1
10Management of acquired aplastic anemia in children显示文摘Korthof ET Békássy AN Hussein AA 2013Bone Marrow Transplant2013,48,2:1
11Extent of pre-operative L-DOPA-induced dyskinesia predicts the severity of graft-induced dyskinesia after fetal dopamine cell transplantation显示文摘Joanna García Thomas Carlsson Máté D?br?ssy Guido Nikkhah Christian Winkler 2011Experimental Neurology2011,,2:1
12Diffeuenees in clinical and laborarory diagnksic characterisies of penicilliosis marneffei in human immunodeficieney virus(HIV)-and nonHIV-infecfed patients显示文摘WANG SSY WANG KH HUI WT 2001J Clin Microbiol2001,39,12:1
13Bringing an old drug to a new treatment strategy in treating FLT-ITD AML-combination of homoharringtonine and serafenib 显示文摘Ho ESK Lain SSY Man CH 2014Blood ( ASH annual meeting Abstracts )2014,124,21:1
14Imported PER-1 producing Pseudomonas aeruginosa,PER-1 producing Acinetobacter baumannii and VIM-2-producing Pseudomonas aeruginosa strains in Hungary显示文摘Szabó D Szentandrássy J Juhász Z 2008Ann Clin Microbiol Antimicrob2008,7,:1
15Blood flow volume quantification of cerebral ischemia: comparison of three noninvasive imaging techniques of carotid and vertebral arteries显示文摘Ho SSY Chan YL Yeung DKW 2002AJR2002,178,3:1
16Photovohaic solarpump adaptability in the agricultural sector显示文摘HAGYM SSY Zoh6n S LE Bcalint P6ter 2011Debreceni M szaki K zlem6nyek2011,,3:1
17Comparative analysis of spices decontaminated by ethylene oxide or gamma radiation显示文摘Farkas J Andr ssy E 1988Acta Alimentaria1988,17,1:1
18Serodiagnosis of Penicillium marneffei infection显示文摘Yuen KY Wong SSY Tsang DNC 0,,05:1
19Treatment with the fibrinolytic inhibitor tranexamic acid--risk for thrombosis?显示文摘Békássy Z Astedt B 1990Acta Obstet Gynecol Scand1990,69,4:1
20Purification and in vitro-phospholabeling of secretary envelope proteins E1 and E2 of hepatitis C virus expressed in insect cells显示文摘 Schmid G Mous J 1996Virus Res1996,45,:1
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