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| 1 | National trends in resection of the distal pancreas显示文摘AIM:To investigate national trends in distal pancreatectomy(DP) through query of three national patient care databases.METHODS:From the Nationwide Inpatient Sample(NIS,2003-2009),the National Surgical Quality Improvement Project(NSQIP,2005-2010),and the Surveillance Epidemiology and End Results(SEER,2003-2009) databases using appropriate diagnostic and procedural codes we identified all patients with a diagnosis of a benign or malignant lesion of the body and/or tail of the pancreas that had undergone a partial or distal pancreatectomy.Utilization of laparoscopy was defined in NIS by the International Classification of Diseases,Ninth Revision correspondent procedure code;and in NSQIP by the exploratory laparoscopy or unlisted procedure current procedural terminology codes.In SEER,patients were identified by the International Classification of Diseases for Oncology,Third Edition diagnosis codes and the SEER Program Code Manual,third edition procedure codes.We analyzed the databases with respect to trends of inpatient outcome metrics,oncologic outcomes,and hospital volumes in patients with lesions of the neck and body of the pancreas that underwent operative resection.RESULTS:NIS,NSQIP and SEER identified 4242,2681 and 11 082 DP resections,respectively.Overall,laparoscopy was utilized in 15%(NIS) and 27%(NSQIP).No significant increase was seen over the course of the study.Resection was performed for malignancy in 59%(NIS) and 66%(NSQIP).Neither patient Body mass index nor comorbidities were associated with operative approach(P = 0.95 and P = 0.96,respectively).Mortality(3% vs 2%,P = 0.05) and reoperation(4% vs 4%,P = 1.0) was not different between laparoscopy and open groups.Overall complications(10% vs 15%,P < 0.001),hospital costs [44 741 dollars,interquartile range(IQR) 28 347-74 114 dollars vs 49 792 dollars,IQR 13 299-73 463,P = 0.02] and hospital length of stay(7 d,IQR 4-11 d vs 7 d,IQR 6-10,P < 0.001) were less when laparoscopy was utilized.One and two year survival after resection for malignancy were unchanged over the course of the study(ductal adenocarinoma 1-year 63.6% and 2-year 35.1%,P = 0.53;intraductal papillary mucinous neoplasm and nueroendocrine 1-year 90% and 2-year 84%,P = 0.25).The majority of resections were performed in teaching hospitals(77% NIS and 85% NSQIP),but minimally invasive surgery(MIS) was not more likely to be used in teaching hospitals(15% vs 14%,P = 0.26).Hospitals in the top decile for volume were more likely to be teaching hospitals than lower volume deciles(88% vs 43%,P < 0.001),but were no more likely to utilize MIS at resection.Complication rate in teaching and the top decile hospitals was not significantly decreased when compared to non-teaching(15% vs 14%,P = 0.72) and lower volume hospitals(14% vs 15%,P = 0.99).No difference was seen in the median number of lymph nodes and lymph node ratio in N1 disease when compared by year(P = 0.17 and P = 0.96,respectively).CONCLUSION:There appears to be an overall underutilization of laparoscopy for DP.Centralization does not appear to be occurring.Survival and lymph node harvest have not changed. | Armando Rosales-Velderrain Steven P Bowers Ross F Goldberg Tatyan M Clarke Mauricia A Buchanan John A Stauffer Horacio J Asbun | 2012 | World Journal of Gastroenterology2012，18，32： | 8 |
| 2 | Gastroenteropancreatic neuroendocrine tumours显示文摘 | Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin | 2008 | Lancet Oncology2008，，1： | 8 |
| 3 | N-acetylcysteine treats intravenous amiodarone induced liver injury显示文摘We report a case of intravenous(IV) amiodarone drug induced liver injury(DILI).The patient received IV N-acetylcysteine(NAC) which resulted in a rapid improvement in liver enzymes.While the specific mechanisms for the pathogenesis of IV amiodaroneDILI and the therapeutic action of IV NAC are both unknown, this case strongly implies at least some commonality.Because IV amiodarone is indicated for the treatment of serious cardiac arrhythmias in an intensive care unit setting, some degree of ischemic hepatitis is likely a cofactor in most cases. | Matthew L Mudalel Kartikeya P Dave James P Hummel Steven F Solga | 2015 | World Journal of Gastroenterology2015，21，9： | 5 |
| 4 | Upper airway epi- thelial structural changes in obstructive sleep- disordered breathing 显示文摘 | PAULSEN F P STEVEN P TSOKOS M | 2002 | Am J Respir Crit Care Med2002，166，4： | 1 |
| 5 | Development of a vibrating cassava root harvester显示文摘 | Gupta C P Stevens W F Paul S C | 1999 | Agricultural Mechanization in Asia Africa and Latin America1999，30，1： | 1 |
| 6 | A Simple Method for Calibra- ting Force Plates and Force Treadmills Using an Instrumented Pole 显示文摘 | Steven H C Peter G A Daniel P F | 2009 | Gait and Posture2009，29，： | 1 |
| 7 | Boron isotope evidence for the involvement of non-marine evaporites in the origin of the Broken Hills ore deposits 显示文摘 | Palmer M R Stevens B P J | 1989 | Nature1989，342，： | 1 |
| 8 | Preoperative lower esophageal sphincter pressure affects outcome of laparoscopic esophageal myotomy for achalasia显示文摘 | Mustafa A Arain Jeffrey H Peters Anan P Tamhankar Giuseppe Portale Gideon Almogy Steven R DeMeester Peter F Crookes Jeffrey A Hagen Cedric G Bremner Tom R DeMeester | 2004 | Journal of Gastrointestinal Surgery2004，，3： | 1 |
| 9 | Origin and significance of tourmaline-rich rocks in the Broken Hills district,Australia 显示文摘 | Palmer M R Stevens B P J | 1994 | Econ Geol1994，88，： | 1 |
| 10 | Carboxylation of C-H bonds using N-heterocyclic carbene gold ( I ) complexes 显示文摘 | Ine I F Boogaerts Steven P Nolan | 2010 | AM Chem Soc2010，132，26： | 1 |
| 11 | Community Resilience as a Metaphor, Theory, Set of Capacities, and Strategy for Disaster Readiness显示文摘 | Norris F H Stevens S P Pfefferbaum B Wyche K F Pfe{-ferhaum R L | 2008 | A- merican Journal of Community Psychology2008，41，12： | 1 |
| 12 | Proteome analysis:biological assay or data archive显示文摘 | Paul A H Steven P G Daniel F | 1998 | Electrophoresis1998，19，： | 1 |
| 13 | A prospective study of the effects of behavioral symptoms on the institutionalization of patients with dementia 显示文摘 | De - Vugt ME Stevens F Aalten P | 2005 | International psychogeriatrics2005，17，4： | 1 |
| 14 | Antitumoractivity and pharmacokinetics in mice of 8-carbamoyl-3-methyl-imidazo-l,2,3,5-tetrazin-4(3H)-one(CCRG81045; M & B 39831),a novel drug with potential as analternative to dacarbazine 显示文摘 | Stevens M F Hickman J A Langdon S P | 1987 | Cancer Res1987，47，22： | 1 |
| 15 | The Linear Angiosperm Phylogeny Group (LAPG) III: a linear sequence of the families in APG III显示文摘 | HASTON E RRCHARDSON J E STEVENS P F | 2009 | Botanical Journal of the Linnean Society2009，161，2： | 1 |
| 16 | A prospective study of the effects of behavioral symptoms on the institutionalization of patients with dementia显示文摘 | DE-VUGT M E STEVENS F AALTEN P | 2005 | Int Psychogeriatr2005，17，4： | 1 |
| 17 | Gastroenteropancreatic neuroendocrine tumours显示文摘 | Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin | 2008 | Lancet Oncology2008，，1： | 1 |
| 18 | Coenzyme Q10 in cardiovascular disease显示文摘 | SALVATOR P SILVANA F STEVEN J | 2007 | Mitochondrion2007，7，1： | 1 |
| 19 | Bayesian forecasting显示文摘 | Harrison P J Stevens C F | 1976 | Journal of theRoyal Statistical Society1976，3，： | 1 |
| 20 | Aseptic meningitis after posterior fossa surgery treated by pseudomeningo- cele closere 显示文摘 | HILLIER C E STEVENS A P THOMAS F | 2000 | J Neurol Neurosurg Psychiatry''2000，68，2： | 1 |
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