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76篇 您的检索式:作者名="SUGAI N"
    题名 作者 年代 出处 被引量
1Celiac disease serology in patients with different pretest probabilities: Is biopsy avoidable?显示文摘AIM: To establish the diagnostic performance of sev-eral serological tests, individually and in combination, for diagnosing celiac disease (CD) in patients with different pretest probabilities, and to explore potential se- rological algorithms to reduce the necessity for biopsy. METHODS: We prospectively performed duodenal biopsy and serology in 679 adults who had either high risk (n = 161) or low risk (n = 518) for CD. Blood samples were tested using six assays (enzyme-linked immunosorbent assay) that detected antibodies to tissue transglutaminase (tTG) and deamidated gliadin peptide (DGP). RESULTS: CD prevalence was 39.1% in the high-risk population and 3.3% in the low-risk group. In high-risk patients, all individual assays had a high diagnostic efficacy [area under receiving operator characteristic curves (AU ROC): 0.968 to 0.999]. In contrast, assays had a lower diagnostic efficacy (AU ROC: 0.835 to 0.972) in the low-risk group. Using assay combinations, it would be possible to reach or rule out diagnosis of CD without biopsy in 92% of cases in both pretest populations. We observed that the new DGP/tTG Screen assay resulted in a surplus compared to more conventional assays in any clinical situation. CONCLUSION: The DGP/tTG Screen assay could be considered as the best initial test for CD. Combinations of two tests, including a DGP/tTG Screen, might be able to diagnose CD accurately in different clinical scenarios making biopsy avoidable in a high proportion of subjects.Emilia Sugai María L Moreno Hui J Hwang Ana Cabanne Adriana Crivelli Fabio Nach-man Horacio Vázquez Sonia Niveloni Julio Argonz Roberto Mazure Graciela La Motta María E Caniggia Edgardo Smecuol Néstor Chopita Juan C Gómez Eduardo Maurińo Julio C Bai 2010World Journal of Gastroenterology2010,16,25:4
2Microbial hydrolysis as a potent method for the preparation of optically active nitriles, amides and carboxylic acids 显示文摘Kakeya H Sakai N Sugai T Ohta H 1991Tetrahedron Lett1991,32,10:1
3Ion conductive characteristics of alkylborane type and boric ester type polymer electrolytes derived from mesitylborane 显示文摘MATSUMI N SUGAI K OHNO H 2003Macromolecules2003,36,:1
4DNA mapping of gastric cancers using flow cytometric analysis显示文摘Sugai T Uesugi N Habano W 2000Cytometry2000,42,5:1
5DNA mapping of gastric cancers using flow cytometric analysis显示文摘 Uesugi N Habano W 2000Cytometry2000,42,5:1
6Postoperative pain relief by patient eontrolled anal- gesia using intravenous pento2oeine 显示文摘Sugai N et M 1995Masui1995,44,2:1
7Increased in situ expression of nitric oxide synthase inhuman colorectal cancer 显示文摘Yagihashi N Kasajima H Sugai S 2001Virchows Arch2001,436,2:1
8Delivery of plasmid DNA expressing small interference RNA for TGF-beta type II receptor by cationized gelatin to prevent interstitial renal fibrosis显示文摘Kushibiki T Nagata-Nakajima N Sugai M 2005J Control Release2005,105,3:1
9High-yield synthe-sis of single-walled carbon nanotubes on MCM41 u-sing catalytic chemical vapor decomposition of acety-lene显示文摘Ramesh P Kishi N Sugai T 2006Journal of Physics Chemical B2006,110,2:1
10Increased in situ expression of nitric oxide synthase in human colorectal cancer显示文摘Yagihashi N Kasajima H Sugai S 2000Virchows Arch2000,436,2:1
11Systematic cognitive behavioral approach for oral hygiene instruction: A short -termstudy 显示文摘Kakudate N Morita M Sugai M 2009Patient Edu Couns2009,74,2:1
12Postoperative pain relief by patient controlled analgesia using intravenous pentazocine显示文摘SUGAI N YAJIMA C CHINZEI M 1995Masui1995,44,2:1
13Delivery of plasmid DNA expressing small interference RNA for TGF-beta type II receptor by cationized gelatin to prevent interstitial renal fibrosis 显示文摘Kushibiki T Nagata-Nakajima N Sugai M 2005J Control Release2005,105,3:1
14Increased in situ expression of nitric oxide synthase in human colorectal cancer 显示文摘Yagihashi N Kasajima H Sugai S 2000Virchows Arch2000,436,2:1
15Pdx-1 enables insulin secretion by regulating synaptotagmin 1 gene expression显示文摘Nakajima-Nagata N Sugai M Sakurai T 2004Biochem Biophys Res Commun2004,318,3:1
16Delivery of plasmid DNA expressing small interference RNA for TGF-beta type II receptor by eationized gelatin to prevent interstitial renal fibrosis显示文摘Kushibiki T Nagata-Nakajima N Sugai M 2005J Control Release2005,105,3:1
17Increased in situ expression of nitric oxide synthase in human colorectal cancer显示文摘YOGIHASHI N KASAJIMAH SUGAI S 2000Virchows Arch2000,436,2:1
18Increased in situ expression of nitric oxide synthase in human colorectal cancer显示文摘Yagihashi N Kasajima H Sugai S 2000Virehows Arch2000,436,2:1
19Dysregulation of adipocytokines re- lated to second-generation antipsychotics in normal fasting glucose pa- tients with schizophrenia 显示文摘Sugai T Suzuki Y Fukui N 2012J Clin Psychopharmacol2012,32,:1
20Systematic cognitive behavioral approach for oral hygiene instruction: a short-term study 显示文摘Kakudate N Morita M Sugai M 2009Patient Educ Couns2009,74,2:1
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