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| 1 | Increased levels of homocysteine in patients with ulcerative colitis显示文摘AIM: To investigate serum levels of homocysteine (Hcys) and the risk that altered levels carry for thrombosis development in ulcerative colitis (UC) patients. METHODS: 55 UC patients and 45 healthy adults were included. Hcys, vitamin B12 and folic acid levels were measured in both groups. Clinical history and thrombo- embolic events were investigated. RESULTS: The average Hcys level in the UC patients was 13.3 ± 1.93 μmmol/L (range 4.60-87) and was higher than the average Hcys level of the control group which was 11.2 ± 3.58 μmmol/L (range 4.00-20.8) (P < 0.001). Vitamin B12 and folic acid average values were also lower in the UC group (P < 0.001). Whenmultivariate regression analysis was performed, it was seen that folic acid deficiency was the only risk factor for hyperhomocysteinemia. Frequencies of thromboembolic complications were not statistically significantly different in UC and control groups. When those with and without a thrombosis history in the UC group were compared according to Hcys levels, it was seen that there were no statistically significant differences. A negative linear relationship was found between folic acid levels and Hcys. CONCLUSION: We could not find any correlations between Hcys levels and history of prior thromboembolic events. | Sabiye Akbulut Emin Altiparmak Firdevs Topal Ersan Ozaslan Metin Kucukazman Ozlem Yonem | 2010 | World Journal of Gastroenterology2010，16，19： | 13 |
| 2 | Celiac Disease Presenting in the Postpartum Period显示文摘 | Ersan ?zaslan Metin Kü?ükazman Firdevs Topal Sabiye Akbulut Emin Alt?parmak | 2007 | Digestive Diseases and Sciences2007，，4： | 1 |
| 3 | An adult case of celiac sprue triggered after an ileal resection for perforated Meckel's diverticulum显示文摘Celiac disease can be triggered by upper abdominal surgery, such as vagotomy, oesophagectomy, pancreatico-duodenectomy, and gastrojejunal anastomosis. Here we report a case of a 24 year-old woman who developed celiac disease after an ileal resection for perforated Meckel's diverticula. This is the first reported celiac case that has been triggered, not by upper abdominal surgery, but after ileal resection for Meckel's diverticula. | Firdevs Topal Sabiye Akbulut Ismail Cagatay Topcu Yasemin Dolek Ozlem Yonem Department of Gastroenterology Cumhuriyet University Cumhuriyet Universitesi Hastanesi 58140 Sivas Turkey | 2009 | World Journal of Gastroenterology2009，15，32： | 0 |
| 4 | Ulcerative colitis presenting as leukocytoclastic vasculitis of skin显示文摘A number of cutaneous changes are known to occur in the course of inflammatory bowel diseases (IBD), including pyoderma gangrenosum, erythema nodosum, perianal disease, erythematous eruptions, urticaria, and purpura. However, occurrence of skin manifestations prior to the development of ulcerative colitis is a rare occasion. Here, we report a case of ulcerative colitis associated with leukocytoclastic vasculitis in which the intestinal symptoms became overt 8 mo after the development of skin lesions. | Sabiye Akbulut Ersan Ozaslan Firdevs Topal Levent Albayrak Burcak Kayhan Cumali Efe | 2008 | World Journal of Gastroenterology2008，14，15： | 0 |
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