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| 1 | 睾丸后精子成熟,不育与高胆固醇血症显示文摘胆固醇是参与哺乳动物生理活动的重要分子,由于它是固醇类激素合成的通用前体物质,因而对生殖系统尤为重要。胆固醇不仅仅对于配子发生起到重要作用,它也是公认的精子功能的调节分子。胆固醇体内平衡的调节对睾丸后精子的成熟至关重要,胆固醇水平失衡会影响到睾丸后调控事件。代谢性脂质紊乱(血脂异常症)会影响男性的生育能力,但大多数这方面的研究是从内分泌/睾丸的角度进行探讨的,而这篇综述将关注像高胆固醇血症这样的特定血脂异常症在哺乳动物精子的睾丸后成熟过程中的有害影响。 | Marjorie Whitfield Xavier PoUet-Villard Rachel Levy Joel R Drevet Fabrice Saez | 2015 | Asian Journal of Andrology2015，17，5： | 8 |
| 2 | Epididymis cholesterol homeostasis and sperm fertilizing ability显示文摘胆固醇,是类固醇荷尔蒙合成的起点,在性腺的水平特别是女性和男繁殖生理学的一个长已知的调节的人,影响胆固醇穿上 gametogenesis。更少对动态平衡可以在 postgonadic 上有的效果胆固醇被知道繁殖功能。最近,几个数据被报导了显示出 imbalanced 胆固醇层次怎么可以特别地影响精子成熟的 testicular 以后事件导致充分肥沃的男配偶子。这评论将集中于那个方面并且实质上在胆固醇怎么为哺乳动物的 epididymis 和精子的生理学是重要的上集中。 | Fabrice Saez Ouvrier and Joel R Drevet | 2011 | Asian Journal of Andrology2011，13，1： | 7 |
| 3 | The epididymal immune balance:a key to preserving male fertility显示文摘Up to 15%of male in fertility has an immuno logical origi n,either due to repetitive infections or to autoimmune resp on ses mainly affecting the epididymis,prostate,and testis.Clinical observations and epidemiological data clearly contradict the idea that the testis confers immune protection to the whole male genital tract.As a consequenee,the epididymis,in which posttesticular spermatozoa mature and are stored,has raised some in terest in recent years when it comes to its immune mecha nisms.In deed,sperm cells are produced at puberty,long after the establishment of self-toleranee,and they possess unique surface proteins that cannot be recognized as self.These are potential targets of the immune system,with the risk of inducing autoantibodies and consequently male infertility.Epididymal immunity is based on a finely tuned equilibrium between efficient immune responses to pathogens and strong tolerance to sperm cells.These processes rely on incompletely described molecules and cell types.This review compiles recent studies focusing on the immune cell types populating the epididymis,and proposes hypothetical models of the organization of epididymal immunity with a special emphasis on the immune response,while also discussing important aspects of the epididymal immune regulation such as tolerance and tumour control. | Allison Voisin Fabrice Saez Joel R Drevet Rachel Guiton | 2019 | Asian Journal of Andrology2019，21，6： | 4 |
| 4 | NH ( 2 ) -terminal truncated HER-2 protein but not full-length receptor is associated with nodal metastasis in human breast cancer 显示文摘 | Molina MA Saez R Ramsey EE | 2002 | Clin Cancer Res2002，8，2： | 1 |
| 5 | Allogeneicbone marrow transplantation in patients who relapseafter autologous transplantation显示文摘 | TSAI T GOODMAN S SAEZ R | 1997 | Bone MarrowTransplant1997，20，： | 1 |
| 6 | PCR-based fingerprinting techniques for rapid detection of animal species in meat products显示文摘 | Saez R Sanz Y Toldr6 F | 2004 | Meat Sci2004，66，3： | 1 |
| 7 | Advanced shape memory alloys processed by powder metallurgy显示文摘 | PI~RI~SAEZ R B RECARTE V N(SM L | 2000 | Advanced Engineering Materials2000，2，12： | 1 |
| 8 | NH (2) - terminal truncated HER -2 protein but not full -length receptor is associated with nodal metastasis in human breast cancer显示文摘 | Molina M A Saez R Ramsey E E | 2002 | Clin Cancer Res2002，8，2： | 1 |
| 9 | Origin, proliferation and differ- entiation of Leydig cells 显示文摘 | Lejeune H Habert R Saez JM | 1998 | J Mol Endocrinol1998，20，1： | 1 |
| 10 | Ureteroscopic lith- otripsy for distal ureteral calculi: comparative evaluation of three different lithotriptors显示文摘 | Salvado JA Mandujano R Saez I | 2012 | J Endourol2012，26，4： | 1 |
| 11 | Idemification of sperm an-tigens as a first step towards the generation of a contraceptive vaccine to decrease fossorial water vole Arvicola terrestris Scher-man proliferations显示文摘 | Grignard E Cadet R Saez F | | 0，，05： | 1 |
| 12 | Transforming growth factor β3 in the fetal and neonatal rat testis: immunolocalization and effect on fetal Leydig cell function显示文摘 | Olaso R Pairault C Saez J | 1999 | Histochem Cell Biol1999，112，3： | 1 |
| 13 | Anx-iety in gastroscopiesxomparison of two nursing interven-tions in endoscopy without sedation显示文摘 | Garcia Sierra R Caballero Saez Y Mena Sanchez R | 2013 | Enfermera-a Glob-al2013，12，32： | 1 |
| 14 | Transforming growth factor beta 3 in the fetal rat testis: immunolocalization and effect on fetal Leydig cell function 显示文摘 | Olaso R Pairault C Saez J | 1999 | Histochem Cell Biol1999，112，3： | 1 |
| 15 | Fracture of magnetoelectroelastic composite materials using boundary element method (BEM)显示文摘 | Garcia-Sanchez F Rojas-Diaz R Saez A Zhang C H | 2007 | Theoretical and Applied Fracture Mechanics2007，47，： | 1 |
| 16 | Evaluation of heavy metal bio-availability from Almagrera pyrite-rich tailings dam (Iberian Pyrite Belt, SW Spain) based on a sequential extraction procedure显示文摘 | Alvarez-Valero A M Saez R Perez-Lopez R | 2009 | Journal of Geochemical Exploration2009，102，2： | 1 |
| 17 | Elicitation of plants and microbial cell systems显示文摘 | Radman R Saez T Bucke C | 2003 | Biotectmology and Applied Biochemistry2003，37，： | 1 |
| 18 | The therapeuticpotential of the calpain family: new aspects显示文摘 | Saez ME Ramirez-Lorca R Moron FJ | 2006 | Drug Discov Today2006，11，： | 1 |
| 19 | p95HER-2 predicts worse outcome in patients with HER-2-positive breast cancer显示文摘 | Saez R Molina MA Ramsey EE | 2006 | Clin Cancer Res2006，12，2： | 1 |
| 20 | Fracture of magnetoelectroelastic composite materials using boundary element method (BEM) 显示文摘 | Garcia-Sanchez F Rojas-Diaz R Saez A Zhang Ch | 2007 | Theoretical and Applied Fracture Mechanics2007，47，： | 1 |
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