|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Molecular Characterization of a Novel Siderophore-independent Iron Transport System in Yersinia显示文摘 | Saken E Rakin A Heesemann J | | 0，，： | 1 |
| 2 | Characterisation of pathogenic Yersinia enterocolitica serogroups by pulsed-field gel electrophoresis of genomic NotI restriction fragments 显示文摘 | Saken E Roggenkamp A Aleksic S | 1994 | J Med Microbiol1994，41，： | 1 |
| 3 | The pesticin receptor of Yersinia enterocolitica: a novel virulence factor with dual function 显示文摘 | Rakin A Saken E Harmson D | 1994 | Mol Microbiol1994，13，2： | 1 |
| 4 | Characterisation of pathogenic Yersinia enterocolitica serogroups by pulsed-field gel electrophoresis of genomic Not Ⅰ restriction fragments 显示文摘 | Saken E Roggenkamp A Aleksic S | 1994 | J Med Microbiol1994，41，： | 1 |
| 5 | Safflower (Carthamus Tinctorius L.) a Potential Source of Drugs against Cryptococcal Infections, Malaria and Leishmaniasis显示文摘In this research we present that Carthamus Tinctorius L.(gen.Asteraceae,otherwise known as Safflower)(Fig.1)may contain agents active in Cryptococcal infections,malaria and Leishmaniasis,as treatment options are becoming scarce due to drug resistance development.Phytochemistry and pharmacological activities(antimicrobial,antimalarial,antileishmanial)of C.tinctorius L.were analyzed.The composition of volatile oil of safflower dried flowers was analyzed by gas chromatography-mass spectrophotometry with flame ionization detector(GC-FID)and in vitro sensitivity assays were performed to assess biological activity.8 known and 3 unknown compounds were detected in the extract(Fig.1).Then the Safflower ointment was manufactured and its acute toxicity study on rats was tested.The volatile oil of C.tinctorius L exhibited activity against Cryptococcus neoformans,Plasmodium falciparum and Leishmania donovani.Safflower volatile oil has anticryptococcal,antimalarial and antileishmanial effects.The prepared ointment had an excellent acute toxicity safety profile. | Aknur Turgumbayeva Gulbaram Ustenova Ubaidilla Datkhayev Khairolla Rahimov Silvijus Abramavicius Agile Tunaityte Kairat Zhakipbekov Kaldanay Kozhanova Saken Tulemissov Ozikhan Ustenova Gulmira Datkayeva Edgaras Stankevicius | 2020 | Phyton-International Journal of Experimental Botany2020，89，1： | 1 |
| 6 | The pesticin receptor of Yersinia enterocolitica : a novel virulence factor with dual function 显示文摘 | RAKIN A SAKEN E HARMSEN D | 1994 | Mol Microbiol1994，13，2： | 1 |
| 7 | The pesticin receptor of Yersinia enterocolitica:a novel virulence factor with dual function显示文摘 | E Saken D Harmsen J Heesemann | 1994 | Mol Microbiol1994，13，： | 1 |
| 8 | Mortality Rates of Ventricular Septal Defect for Children in Kazakhstan: Spatio-Temporal Epidemiological Appraisal显示文摘Objective: The aim is to study the trends in ventricular septal defect (VSD) mortality in children in Kazakhstan.Methods: The retrospective study was done for the period 2011–2020. Descriptive and analytical methods of epidemiologywere applied. The universally acknowledged methodology used in sanitary statistics is used to calculatethe extensive, crude, and age-specific mortality rates. Results: Kazakhstan is thought to be seeing an increase inmortality from VSDs in children. As a result, this study for the years 2011 to 2020 was conducted to retrospectivelyassess data from the central registration of the Bureau of National Statistics that was available throughoutthe nation. Age-standardized mortality data were obtained and compared between age categories. It was shownthat 507 children died from this condition throughout the time period under study. The average annual standardizedmortality rate was 1.88 per 100,000 population and tended to decrease over time. The peak of mortality wasnoted at the age of up to 1 year, namely the neonatal period. Cartogram mortality rates were calculated usingstandardized indicators. Additionally, age-sex variations were taken into account when performing all calculations.Conclusion: In recent years, the death rate from VSD has declined from 1.5 to 0.6 per 100,000 people, withthe trend remaining constant (T = 1.4%, R^(2) = 0.5825). The analysis of mortality trends related to VSD is crucial inboth theoretical and practical aspects, as it enables early detection and treatment of VSDs. The findings of thisstudy will be valuable to public health authorities in developing a strategy to treat VSDs effectively. | Akkerbez Adilbekova Shukhrat Marassulov Bakhytzhan Nurkeev Saken Kozhakhmetov Aikorkem Badambekova | 2023 | Congenital Heart Disease2023，18，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员