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| 1 | Snapshot of HIV pathogenesis in China显示文摘Several reviews have focused on the nature of HIV infection and its spread in various geographical regions of China. In contrast, this review provides a comprehensive update on the prevalence of multiple HIV-1 subtypes, consequent emergence of recombinant and novel forms of HIV-1 in China, and the implications this may have on HIV diversity and the development of effective vaccines. In addition it also examines the dissemination of primary drug resistance in therapy na?ve patients, as well as co-infections with two other important viruses-hepatitis B and C. The main purpose of this review is to provide a current snapshot of HIV-1 pathogenesis in China and possibly shed some light on the future of HIV evolution, and potential challenges for future vaccine and anti-retroviral therapeutics against HIV strains in this area. | Nitin K SAKSENA Bin WANG Megan STEAIN Rong Ge YANG Lin Qi ZHANG | 2005 | Cell Research2005,15,11: | 4 |
| 2 | Widespread genetic heterogeneity in multiple myeloma: implications for targeted therapy显示文摘 | Jens G. Lohr Petar Stojanov Scott L. Carter Peter Cruz-Gordillo Michael S. Lawrence Daniel Auclair Carrie Sougnez Birgit Knoechel Joshua Gould Gordon Saksena Kristian Cibulskis Aaron McKenna Michael A. Chapman Ravid Straussman Joan Levy Louise M. Perkins | 2013 | Cancer Cell2013,,: | 2 |
| 3 | Prognostically relevant gene signatures of high-grade serous ovarian carcinoma显示文摘 | Verhaak Roel G W Tamayo Pablo Yang Ji-Yeon Hubbard Diana Zhang Hailei Creighton Chad J Fereday Sian Lawrence Michael Carter Scott L Mermel Craig H Kostic Aleksandar D Etemadmoghadam Dariush Saksena Gordon Cibulskis Kristian Duraisamy Sekhar | 2013 | Journal of Clinical Investigation2013,,1: | 2 |
| 4 | Evaluation of mannitol effect in patients with acute hepatic failure and acute-on-chronic liver failure using conventional MRI,diffusion tensor imaging and in-vivo proton MR spectroscopy显示文摘AIM:To evaluate the effect of an intravenous bolus of mannitol in altering brain metabolites, brain water content, brain parenchyma volume, cerebrospinal fluid (CSF) volume and clinical signs in controls and in patients with acute liver failure (ALF) and acute-on-chronic liver failure (ACLF), by comparing changes in conventional magnetic resonance imaging (MRI), in vivo proton magnetic resonance spectroscopy (PMRS) and diffusion tensor imaging (DTI) before and after its infusion.METHODS: Five patients each with ALF and ACLF in grade 3 or 4 hepatic encephalopathy and with clinical signs of raised intracranial pressure were studied along with five healthy volunteers. After baseline MRI, an intravenous bolus of 20% mannitol solution was given over 10 min in controls as well as in patients with ALF and ACLF. Repeat MRI for the same position was acquired 30 min after completing the mannitol injection. RESULTS: No statistically significant difference was observed between controls and patients with ALF and ACLF in metabolite ratios, DTI metrics and brain volume or CSF volume following 45 min of mannitol infusion. There was no change in clinical status at the end of post-mannitol imaging. CONCLUSION: The osmotic effect of mannitol did not result in significant reduction of brain water content, alteration in metabolite ratios or any change in the clinical status of these patients during or within 45 min of mannitol infusion. | Vivek A Saraswat Sona Saksena Kavindra Nath Pranav Mandal Jitesh Singh M Albert Thomas Ramkishore S Rathore Rakesh K Gupta | 2008 | World Journal of Gastroenterology2008,14,26: | 2 |
| 5 | Long-term outcome of patients with drug-refractory atrial flutter and fibrillation after single- and dual- site atrial pacing for arrhythmia prevention显示文摘 | Delfaut P Saksena S Prakash A | 1998 | J Am Coll Cardiol1998,32,: | 1 |
| 6 | Ursodeoxycholic acid in the treatment of liver diseases显示文摘 | Saksena S Tandon R K | 1997 | Postgraduate Medical Journal1997,73,856: | 1 |
| 7 | Dual site atrial pacing for the acute and chronic prevention of atrial fibrillation:A prospective study显示文摘 | Saksena S Hill M | 1995 | Am Coll Cardiol1995,25,: | 1 |
| 8 | Microendoscopic discectomy compared with standard microsurgical discectomy for treatment of uncontained or large contained disc herniations显示文摘 | Schizas C Tsiridis E Saksena J | 2005 | Neurosurgery2005,57,4: | 1 |
| 9 | Mathematical model of scheduling clients through welfare agencies 显示文摘 | Saksena J P | 1970 | Canadian Operational Research Society Journal1970,8,3: | 1 |
| 10 | Impartance and effects of attered workplace ergonomics in modem radiology suites 显示文摘 | Harisinghani M G Blake M A Saksena M | 2004 | Radiographics2004,24,2: | 1 |
| 11 | Prevention of recurrent atrial fibrillation with chronic dual site right atrial pacing显示文摘 | Prakash a Hill M | 1996 | J Am Coll Cardiol1996,28,: | 1 |
| 12 | Retrograde Wallerian Degenera- tion of cranial eortieospinal tracts in cervical spinal cord Injury patients using diffusion tensor imaging 显示文摘 | Guleria S Gupta RIL Saksena S | 2008 | J Neumsci Res2008,86,: | 1 |
| 13 | Improved suppression of recurrent atrial fibrilliation with dual site right atrial pacing and antiarrhythmic drug therapy显示文摘 | Saksena S Prakash A Ziegler P | 2002 | J Am Coll Cardiol2002,40,6: | 1 |
| 14 | Comparative evaluation of the cerebral and cerebellar white matter development in pediatric age group using quantitative diffusion tensor imaging 显示文摘 | Saksena S Husain N Malik GK | 2008 | Cerebellum2008,7,39: | 1 |
| 15 | Microendoscopic discectomy compared with standard microsurgical discectomy for treatment of uncontained or large contained disc herniations显示文摘 | Schizas C TsiridiS E Saksena J | 2005 | Neurosurgery2005,57,: | 1 |
| 16 | Electrophysiology and endocardial mapping of induced atrial fibrillation in patients with spontaneous atrial fibrillation显示文摘 | Saksena S Giorgberidze I Mehra R | 1999 | Am J Cardiol1999,83,: | 1 |
| 17 | Carcinoid tumors of the thymus显示文摘 | Kale SB Saksena DS Kole SD | | 0,,: | 1 |
| 18 | Serial changes in diffusion tensor imaging metrics of corpus callosum in moderate traumatic brain injury patients and their corre- lation with neuropsychometric tests: a 2-year follow-up study显示文摘 | Kumar R Saksena S Husain M | 2010 | J H cad Trauma Rehabil2010,25,1: | 1 |
| 19 | Effect of solution pH and ionic strength on the separation of albumin from immuno- globulins (IgG) by selective filtration显示文摘 | Saksena S Zydney A L | 1994 | Biotechnol Bioeng1994,43,: | 1 |
| 20 | The Relationship between Environmental Factors and Management Fraud : An Empirical Analysis 显示文摘 | Saksena Pankaj | 2001 | International Journal of Commerce & Management2001,11,: | 1 |