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12篇 您的检索式:作者名="Salla S"
    题名 作者 年代 出处 被引量
1Increased proliferation activity measured by immunoreactive Ki67 is associated with survival improvement in rectal/recto sigmoid cancer显示文摘AIM: To assess the expression of Ki67 as prognosticator in rectal/recto sigmoid cancer.METHODS: Samples from 146 patients with rectal and recto sigmoid cancer were studied for expression of Ki67 and its prognostic significance in comparison with clinicopathological predictors of survival. Formalin-fixed, paraffin-embedded tissues from 6 (4.1%) patients with T1, 26 (17.8%) with T2, 94 (64.4%) with T3, and 20 (13.7%) with T4 tumors were studied. Ki67 expression was determined immunohistochemically. Samples were divided according to mean value into high (>40%) and low (≤40%) expression. Areas of extensive proliferation (>50%) were defined as 'hot spot' areas. RESULTS: Hot spot areas were present in samples regardless of histopathological grade. Lower TNM and Dukes stage and higher expression of Ki67 and presence of Ki67 hot spot areas in histopathological samples were associated with better survival, whereas no association was observed with histopathological grade (P = 0.78). In Cox multivariate regression analysis, significant prognostic factors were Dukes stage (P<0.001), presence of lymph node metastases (P = 0.015), age (P = 0.035) andpresence of Ki67 hot spot areas (P = 0.044). CONCLUSION: Proliferative activity as measured by Ki67 in rectal cancer is associated with survival improvement compared with patients with low Ki67. Areas of prognostically significant increased proliferation were found independently of histopathological tumor grade.Eeva Salminen Salla Palmu Tero Vahlberg Peter J.Roberts Karl-Owe S(o|¨)derstr(o|¨)m 2005World Journal of Gastroenterology2005,11,21:15
2A practical synthesis of amphiphilic cyclodextrins fully substituted with sugar residues on the primary face显示文摘Sallas F Niikura K Nishimura S I 2004Chemical Communications2004,,5:1
3Long-term exposure to enhanced UV-B radiation has no significant effects on growth or secondary compounds of outdoor-grown Scots pine and Norway spruce seedlings显示文摘Turtola S Sallas L Holopainen J K 2006Envir Pollut2006,144,1:1
4The factorial validity of Maslach burnout inventory-general survey (MBI-GS) across occupational groups and nations显示文摘Nico S Salla T Raija K 2000Journal of Occupational and Organizational Psychology2000,73,1:1
5The effect of food consumption on lumefantrine bioavailability in African children receiving artemether-lumefantrine crushed or dispersible tablets (Coartem) for acute uncomplicated plasmodium falciparum malaria 显示文摘Borrmann S Sallas WM Machevo S 2010Trop Med Int Health2010,15,4:1
6Phar-macokinetic drug interaction in children taking oxcarbazepine显示文摘SALLAS W M MILOSAVLJEV S D'SOUZA J 2003Clin Pharmacol Ther2003,74,2:1
7Long-term exposure to enhanced UV-B radiation has no significant effects on growth or secondary compounds of outdoor-grown Scots pine and Norway spruce seedlings显示文摘TURTOLA S SALLAS L HOLOPAINEN J K 2006Environmental Pollution2006,144,1:1
8A practical synthesis of aniphiphilic cyclodextrins fully substituted with sugar residues on the primary face显示文摘Sallas F Niikura K Nishimura S I 0,,5:1
9Long-term exposureto enhanced UV-B radiation has no significant effects on growth orsecondary compounds of outdoor-grown Scots pine and Norwayspruce seedlings 显示文摘Turtola S Sallas L Holopainen J K ef al 2006Environmental Pollution2006,144,1:1
10Impact of stromal cell composition on BMP-induced chondrogenic differentiation of mouse bone marrow derived mesenchymal cells 显示文摘Hanna T Salla S Teuvo H 2008Experimental Cell Research2008,314,:1
11The factorial validity of the Maslach Burnout Inventory-General Survey(MBI-GS)across occupational groups and nations显示文摘Nico S Salla T Raija K 2000Journal of Occupational and Organizational Psychology2000,73,1:1
12Pharmacokinetic drug interactions in children taking oxcarbazepine 显示文摘Sallas WM Milosavljev S DSouza J 2003Clin Pharmacol Ther2003,74,2:1
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