|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Portal vein thrombosis and arterioportal shunts:Effects on tumor response after chemoembolization of hepatocellular carcinoma显示文摘AIM: To evaluate the effect of portal vein thrombosis and arterioportal shunts on local tumor response in advanced cases of unresectable hepatocellular carcinoma treated by transarterial chemoembolization. METHODS: A retrospective study included 39 patients (mean age: 66.4 years, range: 45-79 years, SD: 7) with unresectable hepatocellular carcinoma (HCC) who were treated with repetitive transarterial chemoembolization (TACE) in the period between March 2006 and October 2009. The effect of portal vein thrombosis (PVT) (in 19 out of 39 patients), the presence of arterioportal shunt (APS) (in 7 out of 39), the underlying liver pathology,Child-Pugh score, initial tumor volume, number of tumors and tumor margin definition on imaging were correlated with the local tumor response after TACE. The initial and end therapy local tumor responses were evaluated according to the response evaluation criteria in solid tumors (RECIST) and magnetic resonance imaging volumetric measurements. RESULTS: The treatment protocols were well tolerated by all patients with no major complications. Local tumor response for all patients according to RECIST criteria were partial response in one patient (2.6%), stable disease in 34 patients (87.1%), and progressive disease in 4 patients (10.2%). The MR volumetric measurements showed that the PVT, APS, underlying liver pathology and tumor margin definition were statistically significant prognostic factors for the local tumor response (P = 0.018, P = 0.008, P = 0.034 and P = 0.001, respectively). The overall 6-, 12- and 18-mo survival rates from the initial TACE were 79.5%, 37.5% and 21%, respectively. CONCLUSION: TACE may be exploited safely for palliative tumor control in patients with advanced unresectable HCC; however, tumor response is significantly affected by the presence or absence of PVT and APS. | Thomas J Vogl Nour-Eldin Nour-Eldin Sally Emad-Eldin Nagy NN Naguib Joerg Trojan Hans Ackermann Omar Abdelaziz | 2011 | World Journal of Gastroenterology2011，17，10： | 20 |
| 2 | A research agenda for improving national Ecological Footprint accounts显示文摘 | Justin Kitzes Alessandro Galli Marco Bagliani John Barrett Gorm Dige Sharon Ede Karlheinz Erb Stefan Giljum Helmut Haberl Chris Hails Laurent Jolia-Ferrier Sally Jungwirth Manfred Lenzen Kevin Lewis Jonathan Loh Nadia Marchettini Hans Messinger Krista Mil | 2008 | Ecological Economics2008，，7： | 2 |
| 3 | Variability of entrainment of cohesive sediments in freshwater显示文摘 | Sally MacIntyre Wilbert Lick Cheng Han Tsai Han Tsai | 1990 | Biogeochemistry1990，，3： | 1 |
| 4 | Factor ⅩⅢ Val 34 Leu A Novel Association With Primary Intracerebral Hemorrhage显示文摘 | Andrew J Hans P Sally B | 1998 | Stroke1998，29，： | 1 |
| 5 | Plant nutrient-acquisition strategies change with soil age显示文摘 | Hans Lambers John A. Raven Gaius R. Shaver Sally E. Smith | 2007 | Trends in Ecology & Evolution2007，，2： | 1 |
| 6 | Safety and immunogenicity of a mosaic vaccine booster against Omicron and other SARS-CoV-2 variants:a randomized phase 2 trial显示文摘An ongoing randomized,double-blind,controlled phase 2 trial was conducted to evaluate the safety and immunogenicity of a mosaic-type recombinant vaccine candidate,named NVSI-06-09,as a booster dose in subjects aged 18 years and older from the United Arab Emirates(UAE),who had administered two or three doses of inactivated vaccine BBIBP-CorV at least 6 months prior to enrollment.The participants were randomly assigned with 1:1 to receive a booster dose of NVSI-06-09 or BBIBP-CorV.The primary outcomes were immunogenicity and safety against severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)Omicron variant,and the exploratory outcome was cross-immunogenicity against other circulating strains.Between May 25 and 30,2022,516 adults received booster vaccination with 260 in NVSI-06-09 group and 256 in BBIBP-CorV group.Interim results showed a similar safety profile between two booster groups,with low incidence of adverse reactions of grade 1 or 2.For immunogenicity,by day 14 post-booster,the fold rises in neutralizing antibody geometric mean titers(GMTs)from baseline elicited by NVSI-06-09 were remarkably higher than those by BBIBP-CorV against the prototype strain(19.67 vs 4.47-fold),Omicron BA.1.1(42.35 vs 3.78-fold),BA.2(25.09 vs 2.91-fold),BA.4(22.42 vs 2.69-fold),and BA.5 variants(27.06 vs 4.73-fold).Similarly,the neutralizing GMTs boosted by NVSI-06-09 against Beta and Delta variants were also 6.60-fold and 7.17-fold higher than those by BBIBP-CorV.Our findings indicated that a booster dose of NVSI-06-09 was well-tolerated and elicited broad-spectrum neutralizing responses against divergent SARS-CoV-2 variants,including Omicron and its sub-lineages. | Nawal Al Kaabi Yun Kai Yang Yu Liang Ke Xu Xue Feng Zhang Yun Kang Yu Qin Jin Jun Wei Hou Jing Zhang Tian Yang Salah Hussein Mohamed Saif ElDein Ze Hua Lei Hao Zhang Shuai Shao Zhao Ming Liu Ning Liu Xiang Zheng Ji Guo Su Sen Sen Yang Xiangfeng Cong Yao Tan Wenwen Lei Xue Jun Gao Zhiwei Jiang Hui Wang Meng Li Hanadi Mekki Mekki Walid Zaher Sally Mahmoud Xue Zhang Chang Qu Dan Ying Liu Jing Zhang Mengjie Yang Islam Eltantawy Peng Xiao Fu Jie Shen Jin Juan Wu Zi Bo Han Li Fang Du Fang Tang Shi Chen Zhi Jing Ma Fan Zheng Ya Nan Hou Xin Yu Li Xin Li Zhao Nian Wang Jin Liang Yin Xiao Yan Mao Jin Zhang Liang Qu Yun Tao Zhang Xiao Ming Yang Guizhen Wu Qi Ming Li | 2023 | Signal Transduction and Targeted Therapy2023，8，2： | 0 |
| 7 | Effects of electron-and hole-current hysteresis on trap characterization in organo-inorganic halide perovskite显示文摘Charge trap density and carrier mobility of perovskite materials are the critical properties of perovskite solar cells.The space charge limited current(SCLC)method,which measures a dark current–voltage(I-V)curve of a single-carrier device has found extensive use for studying the trap density and charge carrier mobility in perovskite materials.Herein,it was found that the electron-and hole-current in organo-lead perovskite-based single-carrier device undergoes significant hysteresis under forward and reverse scanning due to the mobile ions.In addition,it was also observed that measuring history has a detrimental effect on hysteresis resulting in possible overestimation or underestimation of the extracted electrical values from the SCLC measurement.In the forward/reverse scanning process,the mobile ionic defects enhance/shield the charge in the traps due to ionic charging/discharging,thereby increasing/reducing the interface barrier and net charge in the I-V scanning,which in turn affects the determination of transport properties of the carrier.These results raise quite a few doubts over the direct application of classical SCLC measurements for the accurate characterization of intrinsic transport properties of the mixed ionicelectronic perovskite. | Fan Wu Sally Mabrouk Miaomiao Han Yanhua Tong Tiansheng Zhang Yuchen Zhang Raja Sekhar Bobba Quinn Qiao | 2023 | Journal of Energy Chemistry2023，，1： | 0 |
| 8 | 可爱的店 加拿大温哥华某宠物店显示文摘设计师表示,这问可爱的宠物店其设计预算相当有限,它的面积也是如此,只有约88m2。这里原来是一个灯光昏暗的休闲吧,被设计师巧手改造成了现在这样一个明亮、新鲜和具有无限乐趣的场所,而这种环境无论是对宠物还是在此工作或者前来光顾的人们都非常好。 | Dale Kosowan Sally Han 夏天 | 2013 | 室内设计与装修2013，，7： | 0 |
| 9 | 放射状胶质细胞中VCAM1的持续表达维持出生后神经干细胞的胚胎起源显示文摘文章简介在发育过程中,神经干细胞会从胚胎早期的神经上皮细胞转变为放射状胶质细胞。之后,放射状胶质细胞中一个细胞亚群会减慢分裂速度,发育转变为静息态的成体神经干细胞,分布在成年大脑侧脑室周围的室管膜下区。然而,这种胚胎时期的放射状胶质细胞发育转变为成体神经干细胞的机制尚不清楚。 | 胡晓玲 陈果 张三国 郑江莉 Jun Wu Qing-Ran Bai Yue Wang Ji Li Huanhuan Wang Han Feng Jia Li Xicai Sun Qijun Xia Fan Yang Jing Hang Chang Qi Timothy N.Phoenix Sally Temple 沈沁 | 2018 | 科学新闻2018，0，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员