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2篇 您的检索式:作者名="Samet Karahan"
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1Iatrogenic scleroderma renal crisis:A case report and mini literature review for renal crisis显示文摘Background:Systemic sclerosis is a connective tissue disease characterized by fibrosis of the skin and organs,marked changes in microvascular structure,cellular and humoral immune disorders.Renal involvement is more frequent and mainly characterized by moderate proteinuria,elevated serum creatinine levels,and hypertension.The most common kidney involvement in SSc is scleroderma renal crisis(SRC)that is fatal without prompt intervention.Case report:A 52-year-old Caucasian male with known diffuse cutaneous systemic sclerosis was hospitalized with communityacquired pneumonia.On the fifth day after appropriate antibiotic therapy and 60 mg/day methylprednisolone,decreased urine output,arterial hypertension,decreased renal function and pulmonary edema developed.The patient was diagnosed with a scleroderma renal crisis.Emergency hemodialysis was applied to the patient,and captopril 6×25 mg/day and nifedipine 2*60 mg/day treatment were given.He received a routine hemodialysis program for about three months.The hemodialysis program was terminated when the patient’s urine quality and quantity increased.Conclusions:SRC,characterized by malignant hypertension,azotemia,microangiopathic hemolytic anemia,and kidney failure,is one of the most important complications of systemic sclerosis with a poor prognosis without prompt intervention.Steroid use is one of the important risk factors that precipitate SRC development.With angiotensin-converting enzyme inhibitors,survival increased after SRC,the need for dialysis decreased,and usually allowed the discontinuation of dialysis treatment within about 6-18 months.Suspicion of SRC in the presence of the above-mentioned findings in patients with a diagnosis or suspected systemic sclerosis can be considered the most important treatment step.Gülsah Boz Samet Karahan Nurdan Yüksek 2021Discussion of Clinical Cases2021,8,3:0
2中性粒细胞与淋巴细胞比值对伴随前葡萄膜炎的Behet病的影响(英文)显示文摘目的:调查中性粒细胞与淋巴细胞比值(NLR)对伴随前葡萄膜炎的BehCet病(BD)的影响。方法:回顾性研究。研究2004-2013年间我院接收的符合BD诊断的患者。经过筛选735例BD患者,选取135例患者纳入本研究。其中68例患有前葡萄膜炎,其余患者(n=67)没有任何眼部疾患。同时记录前葡萄膜炎患者的全血计数,计算NLR。结果:前葡萄膜炎组的NLR为2.55±0.96。眼部正常组的NLR为1.67±0.50。前葡萄膜炎组的NLR远高于眼部正常组(P〈0.05)。结论:伴随前葡萄膜炎的BD患者的NLR高于眼部正常BD患者。Avci Atil Avci Deniz Cinar Salih Levent Cetinkaya Ali Karahan Samet Erden Abdulsamet Ozyurt Kemal Ulas Yilmaz Ertas Ragip Pangal Emine 2016国际眼科杂志2016,16,4:0
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