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| 1 | Determination of glibenclamide in human plasma by solid-phase extraction and high-performance liquid chromatography显示文摘 | Valdes Santurio J R Gonzalez Porto E | 1996 | Chromatogr B Biomed Appl1996,682,2: | 1 |
| 2 | In vitro influence of temperature on the biological control activity of the fungus Duddingtonia flagrans against Haemonchus contortus in sheep显示文摘 | Rodrigo Buske Janio Morais Santurio Clarissa Vasconcelos Oliveira Liziane Aita Bianchini José Henrique Souza Silva Mario Luiz Rue | 2013 | Parasitology Research2013,,2: | 1 |
| 3 | Fumonisin B1 levels in cereals and feeds from southern Brazil显示文摘 | Mallmann C A Santurio J M Almeida C A A | 2001 | Arq Inst Biol Sao Paulo2001,68,: | 1 |
| 4 | Efficacy of a Brazilian calcium montmorillonite against toxic effects of dietary aflatoxins on broilers reared to market weight 显示文摘 | ECKHARDT J C SANTURIO J M ZANETTE R A | 2014 | British Poultry Science2014,55,2: | 1 |
| 5 | Fumonisin B1 levels in cereals and feeds from southern Brazil显示文摘 | Mallmann C A Santurio J M Almeida CAA Dilkin P | 2001 | Arq Inst Biol Sao Paulo2001,68,: | 1 |
| 6 | Determination of glibenclamide in human plasma by solid-phase extraction and High-performance liquid chromatography显示文摘 | Valdes Santurio JR Gonzalez Porto E | 1996 | J Chromatogr B1996,682,: | 1 |
| 7 | Determination of glibenclamide in human plasma by solid-phase extraction and high-performance liquid chromatography显示文摘 | Valdes Santurio JR Gonzalez Porto E | | 0,,: | 1 |
| 8 | Determination of glibenclamide in human plasma by solid-phase extraction and high-performance liquid chromatography显示文摘 | Gonzalez Porto E | 1996 | J Chromatogr B Biomed Appl1996,682,2: | 1 |
| 9 | Determination of glibenclamide in human plasma by solid-phase extraction and high-performance liquid chromatography显示文摘 | Valdes Santurio JR González Porto E | 1996 | J Chromatogr B Biomed Appl1996,682,2: | 1 |
| 10 | In vitro and in vivo trypanocidal action of aescin and aescin liposomes against Trypanosoma evansi in experimental mice显示文摘Objective:To verify the trypanocidal effectiveness of aescin and aescin liposomes against Trypanosoma evansi in vitro and in vivo.Methods:Aescin and aescin liposomes were used in vitro on trypomastigotes at different concentrations(0.5%,1.0%and 2.0%) and exposure times(0,1,3,6 and 9 h).In vivo tests were performed using mice as the experimental model.Trypanosome evansi infected mice were treated with aescin and aescin liposomes with doses of 60 and 100 mg/kg during 4 d.Results:The three concentrations tested in free form and nanoencapsulated showed trypanocidal activity in vitro,completely eliminating the parasites in small concentration after6 h of assay.Animals treated with aescin(100 mg/kg) and aescin liposomes(100 mg/kg)showed increase in longevity,however without curative effect.Conclusions:Active compounds present in natural products,such as aescin,may potentiate the treatment of trypanosomosis when used in association with other trypanocidal drugs. | Matheus Dellamea Baldissera Nathieli Bianchin Bottari Thirssa Helena Grando Roberto Christ Vianna Santos Ana Julia Figueiro Dalcin Patrfcia Gomes Renata Platcheck Raffin Carine Eloise Prestes Zimmerman Janio Morais Santurio Silvia Gonzalez Monteiro Aleksandro Schafer Da Silva | 2014 | Asian Pacific Journal of Tropical Biomedicine2014,4,12: | 0 |
| 11 | 向肉鸡日粮中添加霉可吸可使真菌毒素的综合毒性降低并对肉鸡进行组织病理估计显示文摘引言
谷物的真菌污染能导致养分的丧失和真菌毒素的产生.这些真菌毒素之一就是由黄曲霉产生的黄曲霉毒素B1.这毒素抑制了蛋白的合成,是一种肝毒素,也是目前知道的最可能的致癌物质.其它霉菌,如镰刀霉菌产生的毒素,也能影响动物生产性能,即使是很小的浓度.各类或各种霉菌产生的毒素同时作用通常要比单个毒素作用更加有害.自然污染情况下,多个毒素污染的现象经常出现.然而,当必须使用被污染的谷物时,吸附剂的使用是阻止真菌毒素的最有用的选择. | S.L Vieira J.M Santurio R.P Ott E.S Viola J.G Almeida G.Eichner V.R Quadros 何梅 吴裕本 | 2005 | 中国家禽2005,27,7: | 0 |
| 12 | Update on pythiosis immunobiology and immunotherapy显示文摘Pythiosis is an invasive, ulcerative, pyogranulomatous disease caused by Pythium insidiosum, a fungus-like oomycete that has been reported to affect humans, horses, dogs, and other mammals mainly in tropical and subtropical areas of the world. The disease is characterized by an eosinophilic granulomatous and a Th2 immune response which in turn helps to protect the fungus from the host cells. Pythiosis can present clinically in subcutaneous, gastrointestinal, and vascular tissues or in a systemically disseminated form depending on the species and site of infection. Changes in iron metabolism and anemia are commonly observed. The diagnosis is accomplished through clinical and pathological features, laboratory characteristics of cultures, serological and molecular tests. Treatment includes radical surgery, antimicrobial drugs, immunotherapy or a combination of these treatments. Immunotherapy is a practical and non-invasive alternative for treating pythiosis which is believed to promote a switch from a Th2 to Th1 immune response, resulting in a favorableclinical response. This therapy has demonstrated cure rates above 70% and 55% in horses and humans but low cure rates in dogs and cats. Despite the curative properties of this type of immunotherapy, the antibodies that are produced do not prevent host reinfection. Thus, development of effective adjuvants and new diagnostic techniques for early disease diagnosis are of utmost importance. The aim of this review was to promote pythiosis awareness and to provide an update about the immunotherapy and immunobiology of this disease. | érico S Loreto Juliana SM Tondolo Régis A Zanette Sydney H Alves Janio M Santurio | 2014 | World Journal of Immunology2014,4,2: | 0 |