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| 1 | Recent advances in vaccination of non-responders to standard dose hepatitis B virus vaccine显示文摘Hepatitis B virus(HBV) infection is a global health problem. It is estimated there are more than 2 billion individuals exposed to the virus and 250 million are chronically infected. Hepatitis B is the cause of more than 600000 annual deaths due to cirrhosis and hepatocellular carcinoma. An effective vaccine exists and preventative initiatives center around universal vaccination especially in those at highest risk. Effective vaccination algorithms have led to a significant decline in the development of new infections and its devastating consequences. The vaccine is administered intramuscularly in three doses, with 95% showing long lasting serologic immunity. An additional fourth dose or a repeated higher dose three course regimen is given to those that fail to show immunity. Despite these additional regimens, some remain vulnerable to hepatitis B and are deemed nonresponders. Individuals with chronic disease states such as kidney disease, liver disease, diabetes mellitus, as well as those with a genetic predisposition, and those on immunomodulation therapy, have the highest likelihood of non-response. Various strategies have been developed to elicit an immune response in these individuals. These include increased vaccination dose, intradermal administration, alternative adjuvants, alternative routes of administration, co-administration with other vaccines, and other novel therapies. These alternative strategies can show improved response and lasting immunity. In summary, HBV vaccination is a major advance of modern medicine and all individuals at risk should be sought and vaccinated with subsequent adequate titers demonstrated. | Saqib Walayat Zohair Ahmed Daniel Martin Srinivas Puli Michael Cashman Sonu Dhillon | 2015 | World Journal of Hepatology2015，7，24： | 12 |
| 2 | Somatic embryogenesis in wild relatives of cotton (Gossypium Spp.)显示文摘Wild cotton species can contribute a valuable gene pool for agronomically desirable cultivated tetraploid cultivars. In order to exploit diploid cotton a regeneration system is required to achieve transformation based goals. The present studies aimed at optimizing the conditions for regeneration of local varieties as well as wild species of cotton. Different callus induction media were tested with varying concentrations of hormones in which sucrose was used as nutritional source. Different explants (hypo-cotyls, cotyledon, root) were used to check the regeneration of both local cotton plants and wild relatives using T & G medium, BAP medium, CIM medium, EMMS medium, and cell suspension medium. Different stages of embryogenicity such as early torpedo stage, late torpedo stage, heart stage, globular stage and cotyledonary stage were observed in wild relatives of cotton. The results of this study pave the way for establishing future transformation methods. | RAO Abdul Qayyum HUSSAIN S. Sarfraz SHAHZAD M. Saqib BOKHARI S. Yassir Abbas RAZA M. Hashim RAKHA Allah MAJEED A. SHAHID A. Ali SALEEM Zafar HUSNAIN Tayyab RIAZUDDIN S. | 2006 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2006，7，4： | 9 |
| 3 | 超高效液相色谱-串联质谱法同时检测果汁中7种甜味剂显示文摘建立了超高效液相色谱-串联质谱同时检测果汁中甜蜜素、糖精钠、安赛蜜、三氯蔗糖、阿斯巴甜、纽甜和甜菊苷等7种甜味剂的方法。实验以甲醇和水作为流动相,柱温40℃,样品经甲醇提取,HLB固相萃取小柱净化。采用电喷雾离子源(ESI)多反应监测(MRM)模式检测,外标法定量。结果表明,7种甜味剂在0.05~2.0 mg/L范围内线性关系良好,所得方程相关系数均大于0.99,检出限为0.000 1~0.003 8 mg/L,定量限为0.000 35~0.013 mg/L。以0.1、0.2、0.3、30、500 mg/L浓度水平做加标回收试验,平均回收率为73.0%~118.8%,RSD为0.30%~19.2%。该法优化了前处理过程,操作简便、快速、灵敏、准确,适用于果汁中7种甜味剂的快速测定。 | 闫震 聂继云 李志霞 李静 程杨 SAQIB Farooq | 2018 | 农产品质量与安全2018，，4： | 7 |
| 4 | Evaluation of sugar and organic acid composition and their levels in highbush blueberries from two regions of China显示文摘Sweet and sour are the most important taste of blueberries,and they are produced by sugar and acid,respectively.Their contributions to the taste depend not only on the levels of sugar and acid,but also on the types and relative proportions of sugar and acid.Therefore,it is very important to evaluate the composition and levels of sugar and acid in blueberries.Regional differences and variety diversity also affect the sugar and acid characteristics of fruits.Therefore,this study selected two main producing regions in northern China(Weihai and Yingkou)to examine the sugar and acid characteristics of 11 common blueberry cultivars.The indexes measured included soluble sugars,organic acids,soluble solid content and titratable acidity.The results showed that glucose and fructose were the major sugars,and citric acid and quinic acid were the major organic acids.Correlation analysis showed that glucose,fructose,and sucrose were positively correlated with total sugar content;the citric acid content was positively correlated with the titratable acidity and total organic acids.Titratable acidity,glucose,fructose,sucrose,total sugar content,citric acid,shikimic acid and total acid content of the blueberries varied significantly between regions(P<0.05).In general,compared with Weihai blueberries,Yingkou blueberries had higher sugar content and lower acid content.The results of this study may provide useful references for the evaluation of sweet and sour flavors and cultivar selection of blueberries. | ZHANG Jia NIE Ji-yun LI Jing ZHANG Hui LI Ye Saqib FAROOQ Syed Asim Shah BACHA WANG Jie | 2020 | Journal of Integrative Agriculture2020，19，9： | 6 |
| 5 | Computational fluid dynamics simulation on the longwall gob breathing显示文摘In longwall mines, atmospheric pressure fluctuations can disturb the pressure balance between the gob and the ventilated working area, resulting in a phenomenon known as ‘‘gob breathing'. Gob breathing triggers gas flows across the gob and the working areas and may result in a condition where an oxygen deficient mixture or a methane accumulation in the gob flows into the face area. Computational Fluid Dynamics(CFDs) modeling was carried out to analyze this phenomenon and its impact on the development of an explosive mixture in a bleeder-ventilated panel scheme. Simulation results indicate that the outgassing and ingassing across the gob and the formation of Explosive Gas Zones(EGZs) are directly affected by atmospheric pressure changes. In the location where methane zones interface with mine air, EGZ fringes may form along the face and in the bleeder entries. These findings help assess the methane ignition and explosion risks associated with fluctuating atmospheric pressures. | Samuel A.Lolon Jürgen F.Brune Gregory E.Bogin Jr. John W.Grubb Saqib A.Saki Aditya Juganda | 2017 | International Journal of Mining Science and Technology2017，27，2： | 5 |
| 6 | Removing ammonia from air with a constant pH, slightly acidic water spray wet scrubber using recycled scrubbing solution显示文摘 | Ahmad Kalbasi Ashtari Amir M. Samani Majd Gerald L. Riskowski Saqib Mukhtar Lingying Zhao | 2016 | Frontiers of Environmental Science & Engineering2016，10，6： | 4 |
| 7 | 乌尔逊凹陷苏仁诺尔CO_(2)气藏主控因素分析显示文摘乌尔逊凹陷苏仁诺尔走滑断裂带西部南屯组发育天然CO_(2)气藏。利用测井、地震、岩心、生产数据等资料,采用序贯高斯模拟方法,建立苏仁诺尔气田南屯组三维地质模型,包括构造模型(地层、断裂带)、岩性模型、物性模型,分析乌尔逊凹陷南屯组的地层格架、断裂分布,以及砂岩储层和物性的三维空间展布特征。结果表明:乌尔逊凹陷苏仁诺尔气田南屯组储层具有低孔隙度、低渗透率的特点,CO_(2)气藏主要分布于断裂活动带构造高点。苏仁诺尔走滑断裂带作为运移通道,对CO_(2)气藏分布起决定性作用;储层岩性和物性在控制CO_(2)气藏聚集和分布中起次要作用。该结果对寻找研究区CO_(2)气藏及后期勘探开发具有指导意义。 | 齐宁 薛海涛 卢双舫 杨金秀 卢明月 夏萦 曹怿昕 MUHAMMAD Saqib RAYON Abrams | 2021 | 东北石油大学学报2021，45，3： | 3 |
| 8 | Joint Design of QC-LDPC Codes for Coded Relay Cooperation显示文摘This paper proposes an effective method to jointly design girth-4 cycle-free Quasi-cyclic(QC) Lowdensity parity-check(LDPC) codes for multi-relay cooperation in a Rayleigh fading channel, where the joint iterative decoding by Min-sum algorithm(MSA) based on the introduced joint Tanner graph is also presented at the destination. Theoretical analysis and simulation show that the proposed QC-LDPC coded cooperation outperforms the randomly coded cooperation under the same conditions. | TANG Lei YANG Fengfan ZHANG Shunwai SAQIB Ejaz LUO Lin | 2016 | Chinese Journal of Electronics2016，25，1： | 3 |
| 9 | An updated Chinese vascular plant tree of life: Phylogenetic diversity hotspots revisited显示文摘Large-scale phylogenies provide a framework for itredisciplinary investigations in taxonomy,evolutionary biology.biogeography,ecology,and conservation.Integration of regional tree of life and species distribution data has greatly promoted spatial phylogenetic studies on biodiversity,floristic assembly,and biogeographic regionalization.In this study,we updated the phylogenetic tree of Chinese vascular plants by integrating data from public databases and sequences newly generated by our laboratory,t如facilitate the exploration of floristic and ecological questions at a country scale.A phylogenetic tree with 15092 tips and 14878 species was obtained,including 13663 species(44.0%)and 2953 genera(95.7%)native to China.Only two familles(Corslaceae and Mitrastemonaceae)and 133 genera native to China are not sampled in this study.Low proportion of sampling is detected In orders with high species diversity and those with low specles dlversity.The Hengduan Mountains,plus the western Qinghail Tibet Plateau and western Xinling,show the greatest gap of target molecular data for angiosperms.Our phylogeny of Chinese wascular plants recovers relationships among and within major lineages that are highly congruent with published phylogenies at a broader scale.Most frilies(98.7%)are supported as monophyleti,and 573 genera(17-90)are recognized a5 non-monophyltic.Finally,hotspots of phylogenetic diversity for the Chinese angiosperms at both the genus and species levels are identified based on our phylogram,implicating conservation priorities for phylogenetic diversity.The updated phylogeny of Chinese vascular plants is publically available to generate subtrees through our automated phylogeny assembly tool SoTree in the DarwinTree platform t/wwwiwntnerenc/fora-sotree-v/index.shtml). | Hai-Hua Hu Bing Liu Y-Shuo Liang Jian-Fei Ye Saddam Saqib Zhen Meng Li-Min Lu Zhi-Duan Chen | 2020 | Journal of Systematics and Evolution2020，58，5： | 3 |
| 10 | Bile cast nephropathy: A case report and review of the literature显示文摘Bile cast nephropathy is a condition of renal dysfunction in the setting of hyperbilirubinemia. There are very few cases of this condition reported in the last decade and a lack of established treatment guidelines. While the exact etiology remains unknown, bile cast nephropathy is presumed to be secondary to multiple concurrent insults to the kidney including direct toxicity from bile acids, obstructive physiology from bile casts, and systemic hypoperfusion from vasodilation. Therapy directed at bilirubin reduction may improve renal function, but will likely need dialysis or plasmapheresis as well. We report our case of bile cast nephropathy and the therapeutic measures undertaken in a middle-aged male with chronic renal insufficiency that developed hyperbilirubinemia and drug-induced liver injury secondary to antibiotic use. He developed acute renal injury in the setting of rising bilirubin. He subsequently had a progressive decline in renal and hepatic function, requiring dialysis and plasmapheresis with some improvement, ultimately requiring transplantation. | Jaymon Patel Saqib Walayat Nikhil Kalva Sidney Palmer-Hill Sonu Dhillon | 2016 | World Journal of Gastroenterology2016，22，27： | 3 |
| 11 | Prevention of gob ignitions and explosions in longwall mining using dynamic seals显示文摘Most, if not all longwall gob areas accumulate explosive methane-air mixtures that pose a deadly hazard to miners. Numerous mine explosions have originated from explosive gas zones(EGZs) in the longwall gob. Since 2010, researchers at the Colorado School of Mines(CSM) have studied EGZ formation in longwall gobs under two long-term research projects funded by the National Institute for Occupational Safety and Health. Researchers used computational fluid dynamics along with in-mine measurements. For the first time, they demonstrated that EGZs form along the fringe areas between the methane-rich atmospheres and the fresh air ventilated areas along the working face and present an explosion and fire hazard to mine workers. In this study, researchers found that, for progressively sealed gobs, a targeted injection of nitrogen from the headgate and tailgate, along with a back return ventilation arrangement, will create a dynamic seal of nitrogen that effectively separates the methane zone from the face air and eliminates the EGZs to prevent explosions. Using this form of nitrogen injection to create dynamic seals should be a consideration for all longwall operators. | Brune Jürgen F. Saki Saqib A. | 2017 | International Journal of Mining Science and Technology2017，27，6： | 3 |
| 12 | Hydrothermal liquefaction of biomass: A review of subcritical water technologies显示文摘 | Saqib Sohail Toor Lasse Rosendahl Andreas Rudolf | 2011 | Energy2011，，5： | 2 |
| 13 | Multi-mycotoxin exposure and risk assessments for Chinese consumption of nuts and dried fruits显示文摘In this study, 15 mycotoxins were detected in 233 nut and dried fruit samples from China. The 15 mycotoxins included aflatoxins(AFs: AFB_1, AFB_2, AFG_1 and AFG_2), trichothecene toxins(TCs: T-2, ZEA, ENA, ENA_1, ENB, ENB_1 and BEA), Alternaria toxins(ATs: TEN, AOH and AME) and ochratoxin A(OTA). The mycotoxins were detected in 47.6% of the samples and all 15 of the mycotoxins were found. Two samples were positive for AFB_1 and exceeded the maximum tolerable levels allowed in China. The contamination levels of the mycotoxins found in nuts, dried jujubes, raisins, dried figs and dried longans were in the ranges of 0.1–462.7, 0.2–247.3, 0.8–10.1, 0.2–384.1 and 0.1–89.2 μg kg–1, respectively. Dried figs(80.0%) had the highest incidence of mycotoxins, followed by dried longans(60.0%), dried jujubes(57.1%), nuts(43.6%) and raisins(26.7%). The estimated daily intake(EDI) values of each individual mycotoxin and all of the mycotoxins collectively were calculated by both the deterministic approach(DA) and the probability approach(PA). For risk characterization, dietary exposure to TCs, ATs and OTA through consumption of nuts and dried fruits according to both approaches, showed no health risk to Chinese adults by exposure to either individual mycotoxins or in combination. To the best of our knowledge, this is the first work in which risk assessment of multimycotoxins is performed, specifically including the emerging ENNs and BEA, in nuts and dried fruits of China. | WANG Yu-jiao NIE Ji-yun YAN Zhen LI Zhi-xia CHENG Yang Saqib Farooq | 2018 | Journal of Integrative Agriculture2018，17，7： | 2 |
| 14 | 基于核密度估计的新浪微博数据地理空间分析:以上海市为例显示文摘为了提取和分析中国上海的社交网络位置数据,通过使用KDE作为空间分析技术来探讨LBSN数据的应用,分析用户参与的新浪微博签到数据与城市特征之间的关系,更重要的是调查上海密集地区的人口密度,以便于相关部门更好地观察和管理。通过使用新浪微博API收集了中国上海10个不同地区在2016年1月~3月期间的数据,并利用核密度估计对基于位置社交网络数据集的新浪微博用户的签到频率进行分析。研究结果表明,核密度估计方法为利用地理空间数据集进行空间模式建模提供了有益的见解。此外,与研究区域的副城区相比,中心城区的密度更大。由此得出结论:通过使用核密度估计技术,可以评估个体的签到行为以及更广泛的总体人口模式。该研究对城市功能及其环境影响、城市可持续性发展和基于城市人口密度的应急响应等领域都有一定的借鉴意义。 | Saqib Ali Haidery 万旺根 曾本冲 Naimat Ullah Khan Muhammad Rizwan Hidayat Ullah | 2019 | 电子测量技术2019，42，21： | 2 |
| 15 | Configurations and Control of Traction Motors for Electric Vehicles:A Review显示文摘In recent decades,worldwide global warming and reduction in petroleum resources have accelerated researcher’s attention to produce alternative sustainable and environmentally clean transportation systems.Electrification of vehicular technology is capable of curbing the environmental pollution problem in an efficient and effective way,due to high efficiency electric motors,development and advancement in the field of power electronic devices,digital signal processing and advanced control techniques.This article presents a comprehensive review on different configurations/architecture of electric vehicles(EVs)and hybrid electric vehicles(HEVs),traction motors for electric propulsion system and high performance speed sensorless control of traction drive.The basic architecture key components of hybrid vehicle and different power train configurations with respect to applications and limitations are discussed.The integral part of electric propulsion system,traction motor classes for desired operational characteristics and limitations are summarized from a system perspective with the latest improvements.High performance traction motor control techniques are discussed with respect to automotive applications.Finally,speed sensorless control techniques research trends as well as an extensive review on rotor speed estimation techniques for robust and efficient sensorless traction drive control are highlighted.This article provides state of the art key global trends and tradeoff of various technologies with future trends and potential areas of research. | Saqib Jamshed Rind Yaxing Ren Yihua Hu Jibing Wang Lin Jiang | 2017 | Chinese Journal of Electrical Engineering2017，3，3： | 2 |
| 16 | Homozygosity mapping of a consanguineous Pakistani family affected with oculocutaneous albinism to Tyrosinase gene显示文摘Dear Sir,Iam Haiba Kaul,from the Department of Biochemistry,University of Health Sciences,Lahore,Pakistan.I write to present a study of oculocutaneous albinism(OCA)in consanguineous Pakistani families.OCA is a genetic defect of melanin biosynthesis that mainly affects eyes,skin and hair.It is a congenital condition and | Muhammad Shakil Muhammad Ikram Ullah Shabbir Hussain Sabika Firasat Saqib Mahmood Haiba Kaul | 2016 | International Journal of Ophthalmology(English edition)2016，9，5： | 2 |
| 17 | Finn Size, Opportuni- ties for Adaptation, and In- house R&D Activity in Developing Countries: The Case of Indian Manufacturing 显示文摘 | Kunaner Nagesh and Moharmned Saqib | 1996 | Research Policy1996，25，5： | 1 |
| 18 | A reconfigurable processor for high speed point multiplication in elliptic curves显示文摘 | Saqib N A Rodriguze-henriquez F Diaz-perez A | 2005 | International Journal of Embedded Systems2005，1，3： | 1 |
| 19 | Systemic risk on the interbank market显示文摘 | Giulia Iori Saqib Jafarey Francisco G. Padilla | 2006 | Journal of Economic Behavior and Organization2006，，4： | 1 |
| 20 | Expression of Engrailed-2 (EN2) protein in bladder cancer and its potential utility as a urinary diagnostic biomarker显示文摘 | Richard Morgan Richard T. Bryan Saqib Javed Francesca Launchbury Maurice P. Zeegers K.K. Cheng Nicholas D. James D. Michael A. Wallace Carolyn D. Hurst Douglas G. Ward Margaret A. Knowles Hardev Pandha | 2013 | European Journal of Cancer2013，，9： | 1 |
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