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您的检索式：作者名="Sara Calvo"
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| 1 | Soil-vegetation relationships in Mediterranean forests after fire显示文摘Background:Wildfires are one of the major environmental concerns in Mediterranean ecosystems.Thus,many studies have addressed wildfire impacts on soil and vegetation in Mediterranean forests,but the linkages between these ecosystem compartments after fire are not well understood.The aim of this work is to analyze soil-vegetation relationships in Mediterranean burned forests as well as the consistency of these relationships among forests with different environmental conditions,at different times after fire,and among vegetation with different functional traits.Results:Our results indicate that study site conditions play an important role in mediating soil-vegetation relationships.Likewise,we found that the nature of soil-vegetation relationships may vary over time as fire effects are less dominant in both ecosystem compartments.Despite this,we detected several common soil-vegetation relationships among study sites and times after fire.For instance,our results revealed that available P content and stoichiometry(C:P and N:P)were closely linked to vegetation growth,and particularly to the growth of trees.We found that enzymatic activities and microbial biomass were inversely related to vegetation growth rates,whereas the specific activities of soil enzymes were higher in the areas with more vegetation height and cover.Likewise,our results suggest that resprouters may influence soil properties more than seeders,the growth of seeders being more dependent on soil status.Conclusions:We provide pioneer insights into how vegetation is influenced by soil,and vice-versa,in Mediterranean burned areas.Our results reflect variability in soil-vegetation relationships among study sites and time after fire,but consistent patterns between soil properties and vegetation were also detected.Our research is highly relevant to advance in forest science and could be useful to achieve efficient post-fire management. | Víctor Fernández-García Elena Marcos Sara Huerta Leonor Calvo | 2021 | Forest Ecosystems2021，8，2： | 0 |
| 2 | Interferon-free treatments in patients with hepatitis C genotype 1-4 infections in a real-world setting显示文摘AIM To investigated the real-world effectiveness and safety of various regimens of interferon-free treatments in patients infected with hepatitis C virus(HCV).METHODS We performed an observational study to analyze different antiviral treatments administered to 462 HCV-infected patients, of which 56.7% had liver cirrhosis. HCV RNA after 4 wk of treatment and at 12 wk after treatment sustained virologic response(SVR) as well as serious adverse events(SAEs) was analyzed first for the whole cohort and then separately in patients who met or did not meet the inclusion criteria of a clinical trial(CT-met and CT-unmet, respectively).RESULTS The most frequently prescribed treatment was simeprevir/sofosbuvir(36.4%), followed by sofosbuvir/ledipasvir(24.9%) and ombitasvir/paritaprevir/ritonavir(r)/dasabuvir(19.9%). Ribavirin(RBV) was administered in 198 patients(42.9%). SVRs occurred in 437/462 patients(94.6%). The SVRs ranged between 93.3% and 100% for genotypes 1-4. SVRs were achieved in 96.2% patients in the CTmet group vs 91.9% patients in the CT-unmet group(P = 0.049). Undetectable HCV RNA at week 4 occurred in 72.9% of the patients. In the univariate analysis, the factors associated with SVRs were lower liver stiffness, absence of cirrhosis, higher platelet count, higher albumin levels, no RBV dose reduction, undetectable HCV RNA at week 4 and CT-met group. In the multivariate analysis, only albumin was an independent predictor of treatment failure(P = 0.04). Eleven patients(2.4%) developed SAEs; 5.2% and 0.7% of the patients in the CT-unmet and CT-met groups, respectively(P = 0.003).CONCLUSION A high proportion of patients with HCV infection achieved SVRs. For patients who did not meet the CT criteria, treatment regimens must be optimized. | Huascar Ramos Pedro Linares Ester Badia Isabel Martín Judith Gómez Carolina Almohalla Francisco Jorquera Sara Calvo Isidro García Pilar Conde Begona álvarez Guillermo Karpman Sara Lorenzo Visitación Gozalo Mónica Vásquez Diana Joao Marina de Benito Lourdes Ruiz Felipe Jiménez Federico Sáez-Royuela 无 | 2017 | World Journal of Gastrointestinal Pharmacology and Therapeutics2017，8，2： | 0 |
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