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| 1 | Intrahepatic natural killer T cell populations are increased in human hepatic steatosis显示文摘AIM: To determine if natural killer T cell (NKT) populations are affected in nonalcoholic fatty liver disease (NAFLD). METHODS: Patients undergoing bariatric surgery underwent liver biopsy and blood sampling during surgery. The biopsy was assessed for steatosis and immunocyte infiltration. Intrahepatic lymphocytes (IHLs) were isolated from the remainder of the liver biopsy, and peripheral blood mononuclear cells (PBMCs) were isolated from the blood. Expression of surface proteins on both IHLs and PBMCs were quantified using flow cytometry. RESULTS: Twenty-seven subjects participated in thisstudy. Subjects with moderate or severe steatosis had a higher percentage of intrahepatic CD3+/CD56+ NKT cells (38.6%) than did patients with mild steatosis (24.1%, P = 0.05) or those without steatosis (21.5%, P = 0.03). Patients with moderate to severe steatosis also had a higher percentage of NKT cells in the blood (12.3%) as compared to patients with mild steatosis (2.5% P = 0.02) and those without steatosis (5.1%, P = 0.05). CONCLUSION: NKT cells are significantly increased in the liver and blood of patients with moderate to severe steatosis and support the role of NKT cells in NAFLD. | Michael Adler Sarah Taylor Kamalu Okebugwu Herman Yee Christine Fielding George Fielding Michael Poles | 2011 | World Journal of Gastroenterology2011，17，13： | 10 |
| 2 | Wnt4/β-Catenin Signaling Induces VSMC Proliferation and Is Associated With Intimal Thickening显示文摘 | Aikaterini Tsaousi Helen Williams Cressida A. Lyon Victoria Taylor Amanda Swain Jason L. Johnson Sarah J. George | 2011 | Circulation Research2011，，4： | 3 |
| 3 | 发生于乳房假体置入女性的间变性大细胞淋巴瘤:173例临床分析显示文摘背景与目的1962年,首例硅胶乳房假体被成功置人体内。1997年,报道了首例与硅胶乳房假体相关的间变性大细胞淋巴瘤(ALCL)。笔者回顾了已发表的37篇文献报道,共79例患者,并收集了94例未报道的病例。方法复习全世界文献。向作者和主治医师寻求文献或病例中缺少的临床和实验数据。由于需要收集的病例信息很多,有时需要在多个地点获得完整的病例信息。因为不是所有被询问的作者和主治医师均提供了信息,所以造成了数据的不完整。结果ALCL病变首先在假体周围血清肿内发现,其肿块附着于包膜,肿块可侵及皮肤,可在区域淋巴结发生,也可在乳房矫形手术中被发现。临床特点呈现多样化,有的仅表现为细胞学阳性结果,肿块自发消退;有的表现为转移性、难治性肿瘤,甚至死亡。其与假体填充物(盐水或硅胶)和置入假体目的(隆乳或乳房再造)没有相关性。在假体信息完整的病例中,患者体内至少置入过1个毛面假体;18例肿块扩散至包膜外,其中9例是致命的。主要的组织化学标记物是cD-30和Alk-1;其他标记物出现频率较低。乳房假体置入女性发生ALCL的风险评估范围是1/500000—1/3000000。结论与乳房假体相关的ALCL是一种新的淋巴瘤,其起源于瘢痕,具有部位和材料特异性,且临床表现呈现多样化,由多因素引起。 | Garry S. Brody Dennis Deapen Clive R. Taylor Lauren Pinter-Brown Sarah Rose House-Lightner James S. Andersen Grant Carlson Melissa G. Lechner Alan L. Epstein 朱利娜 高景恒 张晨 袁继龙 | 2015 | 中国美容整形外科杂志2015，26，12： | 2 |
| 4 | Hemoglobin A1c in early postpartum screening of women with gestational diabetes显示文摘AIM:To assess the utility of hemoglobin A1c(HbA1c) in the early postpartum screening of women with gestational diabetes mellitus(GDM).METHODS:Over a 3 years period,HbA1c estimations were undertaken in addition to and simultaneously with the traditional oral glucose tolerance test(OGTT),in 203 women with GDM as a part of early postpartum screening for dysglycaemia,at 6 wk post-partum.World Health Organization criteria was used for diagnosing diabetes:fasting blood glucose(FBG) ≥ 7.0 mmol/Land/or 2-h postprandial blood glucose(PPBG) ≥ 11.1 mmol/L and/or HbA1c ≥ 48 mmol/mol;and impaired glycaemiastate:impaired fasting glucose 6.1-6.9 mmol/L and/or impaired glucose tolerance 7.8-11.0 mmol/L and/or HbA1c:42-47 mmol/mol.RESULTS:Mean FBG,2-h PPBG and HbA1c were 4.9 ± 0.7 mmol/L,5.6 ± 2.0 mmol/L and 38 ± 5 mmol/mol respectively.FBG,2-h PPBG and HbA1c detected 6(3%),7(3.5%) and 11(5.4%) cases of diabetes respectively,and 11(5.4%),25(12.3%) and 23(11.3%) cases of pre-diabetes state respectively.HbA1c values ≥ 48 mmol/mol(≥ 6.5%) showed a diagnostic sensitivity of 71.4% and specificity of 98.5% for diabetes in comparison to OGTT in receiver operating characteristics curve analysis.At HbA1c cut-off 44 mmol/mol,sensitivity and specificity were 100% and 92.3% respectively [area under the curve:0.98(95%CI:0.96-1.00)].Sensitivity and specificity for detecting high risk 'impaired glycaemia' state [HbA1c 42 mmol/mol(6.0%)] were 28% and 80%,respectively.CONCLUSION:HbA1c level ≥ 48 mmol/mol(≥ 6.5%) has reasonable sensitivity and high specificity in comparison to OGTT for early postpartum screening of diabetes in GDM.At 6 th week postpartum screening,if FBG is normal and HbA1c < 44 mmol/mol OGTT is not recommended. | Mahesh V Katreddy Joseph M Pappachan Sarah E Taylor Radha Indusekhar Ananth U Nayak Alan M Nevill | 2013 | World Journal of Diabetes2013，4，3： | 2 |
| 5 | Six Hundred Fifty Consecutive Pancreaticoduodenectomies in the 1990s: Pathology, Complications, and Outcomes显示文摘 | Charles J. Yeo John L. Cameron Taylor A. Sohn Keith D. Lillemoe Henry A. Pitt Mark A. Talamini Ralph H. Hruban Sarah E. Ord Patricia K. Sauter JoAnn Coleman Marianna L. Zahurak Louise B. Grochow Ross A. Abrams | 1997 | Annals of Surgery1997，，3： | 2 |
| 6 | Long-term mortality from heart disease and lung cancer after radiotherapy for early breast cancer: prospective cohort study of about 300 000 women in US SEER cancer registries显示文摘 | Sarah C Darby Paul McGale Carolyn W Taylor Richard Peto | 2005 | Lancet Oncology2005，，： | 2 |
| 7 | Effect of early treatment on stability of occlusion in patients with Class Ⅱ malocclusion显示文摘 | Sarah S Pavlow Susan P McGorray Marie G Taylor | 2008 | Am J Orthod Dentofac Orthod2008，133，： | 1 |
| 8 | Long-term mortality from heart disease and lung cancer after radiotherapy for early breast cancer: prospective cohort study of about 300 000 women in US SEER cancer registries显示文摘 | Sarah C Darby Paul McGale Carolyn W Taylor Richard Peto | 2005 | Lancet Oncology2005，，8： | 1 |
| 9 | The Use of Soft System Methodology in Practice 显示文摘 | John Mingers and Sarah Taylor | 1992 | Journal of the Operational Research Society1992，，4： | 1 |
| 10 | A model for predicting black tea quality from the carotenoid and chlorophyll composition of fresh green tea leaf 显示文摘 | Sarah Taylor David Baker Philip Owuor | 1992 | J Sci Food Agric1992，58，： | 1 |
| 11 | The use of soft system methodology in practice显示文摘 | Sarah taylor | 1992 | Journal of the Operational Research Society1992，43，32： | 1 |
| 12 | Morphological and functional changes in the colon after massive small bowel resection显示文摘 | Kate L. Healey Julie E. Bines Sarah L. Thomas Guineva Wilson Russell G. Taylor Magdy Sourial Prue M. Pereira-Fantini | 2010 | Journal of Pediatric Surgery2010，，8： | 1 |
| 13 | Mapping public and private spaces of urban agriculture in Chicago through the analysis of high-resolution aerial images in Google Earth显示文摘 | John R. Taylor Sarah Taylor Lovell | 2012 | Landscape and Urban Planning2012，，1： | 1 |
| 14 | GLP-2 Administration Results in Increased Proliferation but Paradoxically an Adverse Outcome in a Juvenile Piglet Model of Short Bowel Syndrome显示文摘 | Prue M Pereira-Fantini Eva S Nagy Sarah L Thomas Russell G Taylor Magdy Sourial Monique CJ Paris Jens J Holst Peter J Fuller Julie E Bines | 2008 | Journal of Pediatric Gastroenterology and Nutrition2008，，1： | 1 |
| 15 | Current diagnosis and treatment of interstitial pregnancy显示文摘 | Nash S. Moawad Sangeeta T. Mahajan Michelle H. Moniz Sarah E. Taylor William W. Hurd | 2010 | American Journal of Obstetrics and Gynecology2010，，： | 1 |
| 16 | Six Hundred Fifty Consecutive Pancreaticoduodenectomies in the 1990s: Pathology, Complications, and Outcomes显示文摘 | Charles J. Yeo John L. Cameron Taylor A. Sohn Keith D. Lillemoe Henry A. Pitt Mark A. Talamini Ralph H. Hruban Sarah E. Ord Patricia K. Sauter JoAnn Coleman Marianna L. Zahurak Louise B. Grochow Ross A. Abrams | 1997 | Annals of Surgery1997，，3： | 1 |
| 17 | Bacteriophage removal in a full-scale membrane bioreactor (MBR) – Implications for wastewater reuse显示文摘 | Sarah Purnell James Ebdon Austen Buck Martyn Tupper Huw Taylor | 2015 | Water Research2015，，： | 1 |
| 18 | Phosphorylation of Immunity-Related GTPases by a Toxoplasma gondii -Secreted Kinase Promotes Macrophage Survival and Virulence显示文摘 | Sarah J. Fentress Michael S. Behnke Ildiko R. Dunay Mona Mashayekhi Leah M. Rommereim Barbara A. Fox David J. Bzik Gregory A. Taylor Benjamin E. Turk Cheryl F. Lichti R. Reid Townsend Wei Qiu Raymond Hui Wandy L. Beatty L. David Sibley | 2010 | Cell Host & Microbe2010，，6： | 1 |
| 19 | Improving the visual quality of commercial development at the rural-urban fringe显示文摘 | William C.Sullivan Sarah Taylor Lovell | | 0，，： | 1 |
| 20 | Prevalence of Ras mutations in thyroid neoplasia显示文摘 | Christopher T.Esapa Sarah J.Johnson PatKendall‐Taylor Tom W. J.Lennard Philip E.Harris | 2001 | Clinical Endocrinology2001，，： | 1 |
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