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	题名	作者	年代	出处	被引量
1	Potential antibacterial activity of berberine against multi drug resistant enterovirulent Escherichia coli isolated from yaks(Poephagus grunniens) with haemorrhagic diarrhoea显示文摘Objective:To evaluate the antimicrobial efficacy of berberine,a plant alkaloid.Methods:Five multi-drug resistant(MDR) STEC/EPEC and five MDR ETEC isolates from yaks with haemorrhagic diarrhoea were selected for the study.Antibacterial activity of berberine was evaluated by broth dilution and disc diffusion methods.The binding kinetics of berberine to DNA and protein was also enumerated.Results:For both categories of enterovirulent Escherichia coli(E.roli) isolates, berberine displayed the antibaclerial effect in a dose dependent manner.The MIC₅₀ of berberine chloride for STEC/EPEC isolates varied from 2.07μM to 3.6μM with a mean of(2.95±0.33)μM where as for ETEC strains it varied from 1.75 to 1.96μM with a mean of(1.87±0.03)μM. Berberine bind more tightly with double helix DNA with Bmax and Kd of(24.68±2.62) and(357.8±57.8),respectively.Berberine reacted with protein in comparatively loose manner with Bmax and Kd of(18.9±3.83) and <286.2±113.6),respectively.Conclusions:The results indicate clearly that berberine may serve as a good antibacterial against multi drug resistant E.coli.	Samiran Bandyopadhyay Pabitra H Patra Achintya Mahanti Dipak K Mondal Premanshu Dandapat Subhasis Bandyopadhyay Indranil Samanta Chandan Lodh Asit K Bera Debasish Bhattacharyya Mihir Sarkar Kishore K Baruah	2013	Asian Pacific Journal of Tropical Medicine2013，6，4：	11
2	Genistein Down-Regulates miR-223 Expression in Pancreatic Cancer Cells显示文摘	Jia Ma Long Cheng Hao Liu Jing Zhang Ying Shi Fanpeng Zeng Lucio Miele Fazlul H Sarkar Jun Xia Zhiwei Wang	2013	Current Drug Targets2013，，10：	2
3	Time-domain electric-field integral equation with central finite difference 显示文摘	Jung B H Sarkar T K	2001	Microwave and Optical Technology Letters2001，31，6：	1
4	Inhibition of nuclear factor kappaB activation in PC3 cells by genistein is mediated via Akt signaling pathway显示文摘	Li Y Sarkar F H	2002	Clin Cancer Res2002，8，7：	1
5	A genetic analysis of the origin of maternal haploid in maize显示文摘	Sarkar K R Coe E H	1966	Genetics1966，54，：	1
6	Down-regulation of miR-221 inhib- its proliferation of pancreatic cancer cells through up-regulation of PTEN, p27 ( kipl ), p57 ( kip2 ), and PUMA 显示文摘	Sarkar S Dubaybo H Ali S	2013	Am J Cancer Res2013，3，5：	1
7	Relaxin increases ubiquitin-dependent degradation of fibronectin in vitro and ameliorates renal fibrosis in vivo 显示文摘	Mcdonald GA Sarkar P Rennke H	2003	Am J Physiol Renal Physiol2003，285，1：	1
8	time-domain CFIE for the analysis of transient scattering from arbitrarily shaped 3D conducting objects显示文摘	Jung B H Sarkar T K	2002	Microwave and Optical Technology Letter2002，34，4：	1
9	Modeling physical un- certainties in dynamic stall induced fluid-strueture interac- tion of turbine blades using arbitrary polynomial chaos显示文摘	Witteveen J A S Sarkar S Bijl H	2007	Computers and Structures2007，85，1114：	1
10	Optical spectroscopic and TEM studies of catanionic micelles of CTAB/SDS and their in-teraction with a NSAID显示文摘	CHAKRABORTY H SARKAR M	2004	Langmuir2004，20，9：	1
11	Expression of Hand2 is sufficient for neurogenesis and cell type - specific gene expression in the enteric nervous system 显示文摘	HENDERSHOT T J LIU H SARKAR A A	2007	Dev Dyn2007，236，1：	1
12	Analysis of transient wave propa- gation in an arbitrary frequency-dispersive media using the associated Laguerre functions in the FDTD-MOD method显示文摘	Jung B H Mei Z Sarkar T K	2012	Microwave and Optical Technology Letters2012，54，4：	1
13	Thrombocytopenic coagulopathy (Kasatxach-Merritt phenonomen ) is association with Kaposiform hemangioendothelioma and not with common infantile hemangioma 显示文摘	SARKAR M MULLIKEN J B KOZAKEWICH H P	1997	Plast Reconstr Surg1997，100，6：	1
14	Manufactured Exports of Developing Countries and Their Terms of Trade since 1965 显示文摘	Sarkar P Singer H	1991	World Development1991，19，4：	1
15	Hint-based cooperative caching显示文摘	Sarkar P Hartman J H	2000	ACM Transactions on Computer Systems ( TOCS )2000，18，4：	1
16	Exosomes in cancer development, metastasis, and drug resistance: a comprehensive review 显示文摘	Azmi A S Bao B Sarkar F H	2013	Cancer Metastasis Rev2013，32，34：	1
17	P - wave evidence as a method for improving algorithm to detect atri- al fibrillation in insertable cardiac monitors 显示文摘	Ptirerfellner H Pokushalov E Sarkar S	2014	Heart Rhythm2014，11，：	1
18	Akt inactivation is a key event in indole-3-carbinol-induced apoptosis in PC-3 cells显示文摘	Chinni S R Sarkar F H	2002	Clin Cancer Res2002，8，4：	1
19	Keyhole supracerebellar transtentorial transcollateral sulcus approach to the lateral ventricle 显示文摘	Marcus HJ Sarkar H Mindermann T	2013	Neurosurgery2013，73，2：	1
20	A genetic analysis of the origin of maternal haploids in maize 显示文摘	Sarkar K R Coe E H	1996	Genetics1996，54，：	1

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